Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
PARD6B
Name:
par-6 family cell polarity regulator beta
Location:
20q13.13
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: par-6 partitioning defective 6 homolog beta (C. elegans)
Symbol:
Description: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.