Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
MTMR3
Name:
myotubularin related protein 3
Location:
22q12.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: myotubularin related protein 3
Symbol:
Description: The protein encoded by this gene is a dual-specificity protein phosphatase that can dephosphorylate proteins at serine, threonine, and tyrosine residues. This protein is structurally similar to myotubularin but in addition contains a FYVE domain, a double zinc finger motif which specifically binds phosphatidylinositol(3)-phosphate. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Three transcript variants encoding three different isoforms have been found for this gene.
