Viewing Gene With DrugMatrix Data


Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/

Symbol: MRPS14
Name: mitochondrial ribosomal protein S14
Location: 01q25.1
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product

DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: mitochondrial ribosomal protein S14
Symbol:
Species: 1000
Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family.