Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
MASP1
Name:
MBL associated serine protease 1
Location:
03q27.3
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor)
Symbol:
Description: The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in two transcript variants encoding two RARF components that are involved in the mannan-binding lectin (MBL) pathway of complement activation. Each isoform is cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases.
