Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
MAP3K12
Name:
mitogen-activated protein kinase kinase kinase 12
Location:
12q13.13
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Annotation Data For: 35 Matched Genes
Value: Leucine-zipper protein kinase
Value: MAPK-upstream kinase
Value: Mixed lineage kinase
Value: dual leucine zipper kinase DLK
Value: mitogen-activated protein kinase kinase kinase 12
Value: leucine zipper protein kinase
Value: protein kinase MUK
Value: Dual leucine zipper bearing kinase
Value: zipper protein kinase
Category: CELLULAR COMPONENT
Value: PLASMA MEMBRANE,GO:0005886
Category: CELLULAR COMPONENT
Value: MEMBRANE FRACTION,GO:0005624
Category: CELLULAR COMPONENT
Value: CYTOSOL,GO:0005829
Category: CELLULAR COMPONENT
Value: CYTOPLASM,GO:0005737
Category: MOLECULAR FUNCTION
Value: TRANSFERASE ACTIVITY,GO:0016740
Category: MOLECULAR FUNCTION
Value: PROTEIN-TYROSINE KINASE ACTIVITY,GO:0004713
Category: MOLECULAR FUNCTION
Value: PROTEIN SERINE/THREONINE KINASE ACTIVITY,GO:0004674
Category: MOLECULAR FUNCTION
Value: PROTEIN HOMODIMERIZATION ACTIVITY,GO:0042803
Category: MOLECULAR FUNCTION
Value: PROTEIN KINASE BINDING,GO:0019901
Category: MOLECULAR FUNCTION
Value: MAGNESIUM ION BINDING,GO:0000287
Category: MOLECULAR FUNCTION
Value: ATP BINDING,GO:0005524
Category: BIOLOGICAL PROCESS
Value: PEPTIDYL-THREONINE PHOSPHORYLATION,GO:0018107
Category: BIOLOGICAL PROCESS
Value: PEPTIDYL-SERINE PHOSPHORYLATION,GO:0018105
Category: BIOLOGICAL PROCESS
Value: HISTONE PHOSPHORYLATION,GO:0016572
Category: BIOLOGICAL PROCESS
Value: AUTOPHOSPHORYLATION,GO:0046777
Category: BIOLOGICAL PROCESS
Value: PROTEIN KINASE CASCADE,GO:0007243
Category: BIOLOGICAL PROCESS
Value: PROTEIN AMINO ACID PHOSPHORYLATION,GO:0006468
Category: BIOLOGICAL PROCESS
Value: JNK CASCADE,GO:0007254
