Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
KALRN
Name:
kalirin RhoGEF kinase
Location:
03q21.1-q21.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: kalirin, RhoGEF kinase
Symbol:
Description: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. An alternatively spliced variant has been described but its full-length sequence has not been determined.