Viewing Gene With DrugMatrix Data

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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: ITGAE
Name: integrin subunit alpha E
Location: 17p13.2
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
Gene | Activity | Annotation | GO | Identifier | Pathway | Signature | Simple | Tissue
Target | Accession | Expression | Synonym | Pathway Gene | Gene Platform | Pathway Target
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Symbol:
View DrugMatrix Gene Data
Species: 1000
Description: ITGAE encodes integrin alpha chain E. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin undergoes post-translational cleavage in the extracellular domain that yields disulfide-linked heavy and light chains, In combination with beta 7 (ITGB7) these chains form the E-cadherin binding integrin known as 'human mucosal lymphocyte-1' antigen (HML-1). This integrin is preferentially expressed on human intestinal intraepithelial lymphocytes (IEL), and in addition to adhesion, it may serve as an accessory molecule for IEL activation.