Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
IL17RB
Name:
interleukin 17 receptor B
Location:
03p21.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: interleukin 17 receptor B
Symbol:
Description: The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
