Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
HNF4A
Name:
hepatocyte nuclear factor 4 alpha
Location:
20q13.12
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: hepatocyte nuclear factor 4, alpha
Symbol:
Description: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.
