Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
HIF3A
Name:
hypoxia inducible factor 3 subunit alpha
Location:
19q13.32
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: hypoxia inducible factor 3, alpha subunit
Symbol:
Description: The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least four transcript variants encoding four different isoforms have been found for this gene.