Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
HES6
Name:
hes family bHLH transcription factor 6
Location:
02q37.3
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: hairy and enhancer of split 6 (Drosophila)
Symbol:
Description: Does not bind DNA itself but suppresses both HES1- mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to up-regulate transcription in its presence. Promotes cell differentation (By similarity).