Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
FGF21
Name:
fibroblast growth factor 21
Location:
19q13.33
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT00968747 | Regulation of FGF21 by Nutritional Challenges | View | |
| NCT04222101 | Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy | View | |
| NCT02118142 | Modulation of Insulin Sensitivity by Betaine Upregulation of FGF21 | View | |
| NCT01018628 | A Clinical Study to Assess the Safety and Pharmacokinetics of SRT2379 in Normal Healthy Male Volunteers | View | |
| NCT04232033 | The Physiological Effects of FGF21 on Alcohol Preference and Glucose Metabolism | View | |
| NCT05232695 | Brown Fat Tissue Related Hormone Levels in Metabolically Healthy and Unhealthy Obese Individuals | View | |
| NCT06569524 | Efficacy and Safety of Recombinant Human FGF21-Fc Fusion Protein for Injection TQA2225AP025 in Adult Subjects With Non-alcoholic Steatohepatitis NASH | View | |
| NCT05764811 | SGLT-2 Inhibitor Effects on Cardiac and Hepatic Metabolic Profiles for the Diabetes Patients Combined With Obesity | View | |
| NCT05843747 | Ex Vivo Transformation of White Adipose Tissue WAT Into Brown Adipose Tissue BAT in Morbidly Obese Patients Using the Ex Vivo Adipocyte Expansion ExAdEx Approach Proof of Concept From White to Brown Adipose Tissue | View | |
| NCT05924295 | Variations in Ketone Metabolism | View | |
| NCT03596554 | X-linked Hypophosphatemia and FGF21 | View | |
| NCT01858597 | Fibroblast Growth Factors 19 and 21 in Gestational Diabetes Mellitus | View | |
| NCT01627067 | Exemestane-RAD001-Metformin | View | |
| NCT01752920 | Phase 12 Study of Derazantinib ARQ 087 in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations | View | |
| NCT02243852 | Effects of Growth Hormone GH Deficiency and Growth Hormone Replacement on Serum Fibroblast Growth Factor 21 FGF21 | View | |
| NCT01512368 | Changes in Serum Fibroblast Growth Factor 21 FGF21 Levels Correlated With Exercise | View | |
| NCT02411825 | Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus T2DM Patients | View | |
| NCT05792982 | Serum Fibroblast Growth Factor-21 Levels During Prolonged Fasting | View | |
| NCT02884791 | FGF21 and Fructose Challenge in Humans | View | |
| NCT05632055 | miRNA microRNA and FGF21 Fibroblast Growth Factor-21 Profile in First Trimester and Gestational Diabetes Prediction | View | |
| NCT03486912 | A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis NASH and Liver Cirrhosis | View | |
| NCT03486899 | A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis NASH and Stage 3 Liver Fibrosis | View | |
| NCT06263725 | Protein Restriction PR for Weight Loss | View | |
| NCT06267235 | Dietary Protein Restriction and Health | View | |
| NCT03611101 | Companion Protocol for ¹³C-Methacetin Breath Tests in BMS NCT03486899 NCT03486912 Referenced Trials | View | |
| NCT04012983 | Possible Role of Gingival Crevicular Fluid Levels of Chemerin and Fibroblast Growth Factor 21 as Biomarkers of Periodontal Disease in Diabetic and Non-diabetic Patients | View | |
| NCT05061485 | The Effect of Macronutrients on Fibroblast Growth Factor 21 FGF21 Secretion | View | |
| NCT04541186 | Study to Explore the Efficacy and Safety of BIO89-100 Pegozafermin in Participants With Severe Hypertriglyceridemia | View | |
| NCT06101433 | The Effect of Soy Isoflavones on Non-alcoholic Fatty Liver Disease and the Level of FGF-21 and Fetuin A | View | |
| NCT06105476 | Effect of Protein and Retinol on Alcohol-induced FGF21 | View | |
| NCT05088005 | Prognostic Biomarkers in CO Poisoning | View | |
| NCT05528393 | Prolactin and FGF21 in Gestational Diabetes Mellitus | View | |
| NCT05937737 | Serum FGF21 Levels and Dietary Total Antioxidant Capacity in Type 2 Diabetes | View | |
| NCT05719142 | Physiological and Eating-behavioral Responses to Viewing Sensory-specific Food Pictures | View | |
| NCT02704468 | FGF21 Can Help Predicting Arterial Stiffness Measured by Cardio-ankle Vascular Index in Renal Transplant Patients | View | |
| NCT03091725 | A Role for FGF21 in Postprandial Nutrient Homeostasis After RYGB | View | |
| NCT03892369 | FGF21 and Its Role in Alcohol Dependence | View |