Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
EGF
Name:
epidermal growth factor
Location:
04q25
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT00111774 | Evaluating ABX-EGF in Patients With Metastatic ColorectalCarcinoma | View | |
| NCT00154102 | Cetuximab Combined With Irinotecan in First-line Therapy for Metastatic Colorectal Cancer CRYSTAL | View | |
| NCT00364715 | Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer | View | |
| NCT01051791 | Phase II Study of RAD001 Head and Neck Cancer | View | |
| NCT00957086 | Study of Post-Op Adjuvant Concurrent Chemo-RT With or Without Nimotuzumab for Head Neck Cancer | View | |
| NCT06494813 | Biochemical Role of Matrix Metalloproteinase -9 in Rheumatoid Arthritis | View | |
| NCT00734890 | Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or Lymphoma | View | |
| NCT01017653 | Panitumumab and Irinotecan for Malignant Gliomas | View | |
| NCT01245660 | A Phase 0 of Neoadjuvant Lapatinib in Infiltrative Bladder Carcinoma Before Cystectomy | View | |
| NCT01520389 | Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment | View | |
| NCT01566578 | A Physiological Study on Downregulation of EGF-receptors in the Skin by Topical Exposition With EGF | View | |
| NCT01691391 | Early Biomarker With 18F-FDG PET for Treatment Optimization of Anti-EGFR Therapy in Patients With Metastatic Colorectal Cancer | View | |
| NCT01916317 | Randomized Controlled Trial to Assess Blockade of Voltage Gated Sodium Channels During Surgery in Operable Breast Cancer | View | |
| NCT02139579 | Efficacy and Safety Study of Bevacizumab Plus Chemotherapy in EGFR-TKI Resistant Non-Squamous Non-Small Cell Lung Cancer | View | |
| NCT02409186 | A Phase III Study of Nimotuzumab Plus Concurrent Chemoradiotherapy in Loco-regional Esophageal Squamous Cell Carcinoma | View | |
| NCT02876081 | Phase II Study of Afatinib as Third- or Further-line Treatment for Patients With Stage IV Bronchial Adenocarcinoma Harboring Wild-type EGFR Expressing the Neurotensin - Neurotensin Receptor Complex | View | |
| NCT02891733 | Retrospective Analysis of the Expression of the Neurotensin Receptor by Metastatic Lung Adenocarcinomas | View | |
| NCT04217785 | Umbilical Cord Serum Versus Conventional Eyedrops | View | |
| NCT03051880 | Preventive Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors | View | |
| NCT03085277 | Bovine Colostrum for Preterm Newborns | View | |
| NCT03623750 | E GFR TKI and EGF-P TI C Ombination in EGFR mutA nt NSCL C | View | |
| NCT05335577 | Role of Urinary Claudin-2 Caveolin-1 and EGF as Diagnostic Biomarkers of Necrotizing Enterocolitis in Preterm Neonates | View | |
| NCT04022434 | Investigation of Supplemental L-alanine in the Management of Dietary Fructose Intolerance | View | |
| NCT04082949 | Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis | View | |
| NCT00684437 | Literacy and Smoking Risk Communications | View | |
| NCT04537130 | Vaccination of Ex-acute COVID-19 Patients With Fibrosing Lung Syndrome at Discharge | View | |
| NCT05481359 | AF-FLOW Registry This Study is to Evaluate Ablamap Software in Patients Undergoing Ablation for Atrial Fibrillation | View | |
| NCT05020275 | Resistance to the Tyrosine Kinase Inhibitor Osimertinib and Pharmacokinetics in Non-small Cell Lung Cancer | View | |
| NCT00111761 | Evaluating Panitumumab ABX-EGF in Patients With Metastatic Colorectal Cancer | View | |
| NCT04298606 | A Vaccine CIMAvax-EGF for the Prevention of Lung Cancer Development or Recurrence | View | |
| NCT00327119 | Phase 2 Study of ABX-EGF Panitumumab in Japanese Subjects With M-colorectal Cancer | View | |
| NCT05912712 | Autologous Platelet-rich Plasma PRP and Thrombin Coagulum for the Topical Treatment of Rectal Mucosal Ulcers | View | |
| NCT00081614 | A Study Evaluating Tarceva in Combination With Avastin Versus Avastin Alone in Treating Metastatic Renal Cell Carcinoma | View | |
| NCT06383884 | Patritumab Deruxtecan in Patients With Solid Tumor Harboring an NRG1 Fusion | View | |
| NCT02923310 | Evaluation of Two Types of PRP in Knee Osteoarthritis | View | |
| NCT01122303 | Corneal Epitheliotropic Factors in Autologous Serum Eye Drops in Nonautoimmune and Stevens-Johnson Syndrome With Dry Eye | View | |
| NCT06444893 | Morphofunctional Gene Inflammation Molecules and Oxidative Stress Analysis in Kidney Tissue of COVID-19 Patients | View | |
| NCT00004879 | Monoclonal Antibody ABX-EGF in Treating Patients With Renal Kidney Prostate Pancreatic Non-Small Cell Lung Colon or Rectal Esophageal or Gastroesophageal Junction Cancer | View | |
| NCT00516685 | Vaccine Therapy in Treating Patients With Non-Small Cell Lung Cancer NSCLC Stages IIIBIV | View | |
| NCT00234416 | IRESSA Combined With Radiotherapy Gemcitabine as First-Line Treatment in Locally Advanced Pancreatic Cancer | View | |
| NCT00059449 | Role of Epidermal Growth Factor EGF in Development of Necrotizing Enterocolitis | View | |
| NCT00051103 | Oral Drug Study In Women With Refractory Metastatic Breast Cancer After First-line or Second-line Herceptin | View | |
| NCT00039273 | Monoclonal Antibody Therapy in Treating Patients With Metastatic Colorectal Cancer | View | |
| NCT00054574 | Monoclonal Antibody Therapy in Treating Patients With Prostate Cancer | View | |
| NCT00061126 | ABX-EGF a Monoclonal Antibody Given to Patients With Prostate Cancer With or Without Tumor in Other Parts of the Body | View | |
| NCT00089635 | Panitumumab ABX-EGF Monotherapy in Patients With Metastatic Colorectal Cancer | View | |
| NCT00091806 | Two Dose Schedules of Panitumumab in Subjects With Advanced Solid Tumors | View | |
| NCT00101920 | ABX-EGF as Second Line Treatment of Advanced Non-Small-Cell Lung Cancer NSCLC | View | |
| NCT00113763 | Evaluating Panitumumab ABX-EGF Plus Best Supportive Care Versus Best Supportive Care in Patients With Metastatic Colorectal Cancer | View | |
| NCT00115765 | PACCE Panitumumab Advanced Colorectal Cancer Evaluation Study | View | |
| NCT00113776 | Evaluating ABX-EGF Extended Therapy in Subjects With MetastaticColorectal Cancer | View | |
| NCT00401401 | Zalutumumab in Combination With Chemotherapy and Radiotherapy in Head and Neck Cancer | View | |
| NCT00425035 | Safety and Efficacy Study of ABX-EGF in Patients With Renal Cancer Part 2 | View | |
| NCT00425204 | Study for Patients Who Have Benefited and Tolerated Prior Panitumumab Treatment | View | |
| NCT00460551 | Zalutumumab in Combination With Chemo-Radiation in a Certain Type of Lung Cancer | View | |
| NCT00477880 | Cetuximab in Treating Patients With Ménétrier Disease at High Risk of Developing Stomach Cancer | View | |
| NCT04466124 | Prospective Cohort Study of Liver Cancer Patients Treated With Proton Beam Therapy | View | |
| NCT01480141 | A Window of Opportunity Trial of Afatinib In Early Stage Non-Small Cell Lung Cancer NSCLC | View | |
| NCT00677924 | Zalutumumab With or Without Irinotecan Chemotherapy in Cetuximab-Refractory Colorectal Cancer | View | |
| NCT01553708 | Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound | View | |
| NCT01574209 | Gut Peptides and Intestinal Permeability in Celiac Disease and Irritable Bowel Syndrome | View | |
| NCT04549064 | Biomarkers of Pancreatic Cancer and New Way to Detection | View | |
| NCT01593995 | EGF Ointment for Erlotinib Skin Lesion | View | |
| NCT00754494 | Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or Adenoma | View | |
| NCT01974180 | Smoking-induced EGF-dependent Reprogramming of Airway Basal Cell Function | View | |
| NCT00857610 | Retinol-induced Dermatitis in Aged Skin | View | |
| NCT00857246 | Pre-operation Chemo and Antibody Therapy Followed by Surgical Resection and Adjuvant Chemoradiation for Gastric Cancer | View | |
| NCT00542308 | Zalutumumab in Non-curable Patients With SCCHN | View | |
| NCT02820233 | Studies of NeuregulinERBB Signaling in Human Heart | View | |
| NCT01099891 | The Clinical Study for Evaluation of Efficacy and Safety of EGF on Oral Mucositis in Radiation Therapy Patients | View | |
| NCT02171637 | Dose Escalation Study of Oral Treatment With BIBW 2992 in Patients With Advanced Solid Tumors | View | |
| NCT01279291 | Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer | View | |
| NCT02420886 | Adding Cytokines to In Vitro Human Culture Media to Improve Embryogenesis and Implantation | View | |
| NCT04995354 | Efficacy of EGF-loaded Self Healing Gel in Treatment of Oral Mucositis | View | |
| NCT01666431 | Single-center Investigator Initiated Pilot Study Investigating the Tumor Response of Squamous Cell Carcinoma Lesions in Patients Under Lapatinib Treatment | View | |
| NCT01681784 | Studies of Biomarkers in Female Lower Urinary Tract Symptoms | View | |
| NCT05191732 | Effect of PRP Versus BMC in Anterior Cruciate Ligament Reconstruction | View | |
| NCT01806220 | Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis | View | |
| NCT02122172 | Afatinib in Advanced Refractory Urothelial Cancer | View | |
| NCT02152943 | Everolimus Letrozole and Trastuzumab in HR- and HER2Neu-positive Patients | View | |
| NCT02391727 | Safety Immunogenicity and Pharmacokinetics of SYN004 in Patients With Solid Tumors | View | |
| NCT04211597 | EGF-loaded Chitosan to Facilitate Healing and Prevent Scar Formation of Cesarean Wound | View | |
| NCT05724589 | The Effectiveness of Epidermal Growth Factor Serum in Improve Facial Skin Hydration Elasticity Pigmentation and Wrinkles | View | |
| NCT02953249 | Wound Healing After Tooth Extraction in Individuals With Type 1 Diabetes Mellitus | View | |
| NCT03216863 | Home Respiratory Rehabilitation in Advanced Lung Cancer Chemotherapy Per os | View | |
| NCT03469167 | Study to Evaluate Efficacy and Safety of Wound Dressing Solution Containing EGF in Patients With Peptic Ulcers Bleeding | View | |
| NCT06381635 | Effect of Aloe Vera Gel and Manuka Honey on Radiation Induced Oral Mucositis | View | |
| NCT05093868 | Electrographic Flow Mapping Validation in Patients With Persistent Atrial Fibrillation EVAL AF | View | |
| NCT05033691 | A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases | View | |
| NCT06011772 | EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer | View | |
| NCT04473963 | FLOW-AF A Study to Evaluate the Ablacon Electrographic FLOW EGF Technology | View | |
| NCT04704245 | Effectiveness of Epidermal Growth Factor-containing Ointment on the Solar Lentigines | View | |
| NCT04919655 | Primary Lymphedema and Mutation CELSR1 Cadherin EGF LAG Seven-pass G-type Receptor 1 | View | |
| NCT06260670 | FLOW EVAL-AF FLOW Mapping Electrogram VALidation in Patients With Persistent Atrial Fibrillation | View | |
| NCT05335720 | Efficacy and Safety Evaluation of EASYEF in Acute Wound Split-thickness Skin Graft Donor Site | View | |
| NCT01977976 | RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF | View | |
| NCT00083616 | Evaluating Panitumumab ABX-EGF Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine Irinotecan and Oxaliplatin Chemotherapy | View | |
| NCT00828451 | Collaborative Research Group for Necrotizing Enterocolitis | View | |
| NCT00910676 | Study About Preventive Treatment of Folliculitis Induced by Epidermal Growth Factor Receptor Inhibitors | View | |
| NCT00093041 | Zalutumumab in Head and Neck Cancer | View | |
| NCT05883631 | RESOLVE-AF Clinical Evaluation of the Ablacath Mapping Catheter and Ablamap System Utilizing Electrographic Flow EGF Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy | View | |
| NCT01094444 | Investigation of the Effect of Vitamin K3-lotion for the Treatment of Cetuximab Induced Folliculitis | View | |
| NCT00144976 | Study of Biological Effect of Tarceva OSI-774 for Patients Stricken by ENT Epidermoid Carcinoma | View | |
| NCT00390455 | Fulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-Positive | View | |
| NCT01374789 | PURO Panitumumab in Combination With GemcitabineCisplatin in Advanced Urothelial Cancer | View | |
| NCT01444118 | A Randomized Trial to Study the Safety and Efficacy of EGF Cancer Vaccination in Late-stage IIIBIV Non-small Cell Lung Cancer Patients | View | |
| NCT05982197 | Curcumin Gel On Radiation Induced Oral Mucositis | View | |
| NCT00828620 | Positron Emission Tomography - Computed Tomography PET-CT Cetuximab Project | View | |
| NCT02187367 | Safety Efficacy Study of EGF Cancer Vaccine to Treat Stage IV Biomarker Positive Wild Type EGF-R NSCLC Patients | View | |
| NCT01389401 | Salivary Epidermal Growth Factor EGF Concentration Before and After Treatment of Reflux Laryngitis | View | |
| NCT00034346 | ABX-EGF in Combination With Paclitaxel and Carboplatin for the Treatment of Advanced Non-Small-Cell Lung Cancer NSCLC | View | |
| NCT00145314 | FLOX in Combination With Cetuximab in First-line Treatment of Colorectal Cancer | View | |
| NCT02284139 | Pilot Trial of EGF Ointment for the Patients With EGFR-i Related Skin Side Effects | View | |
| NCT00317772 | Topotecan and Gefitinib Iressa for Ovarian Peritoneal or Fallopian Tube Cancer | View | |
| NCT00042939 | Irinotecan and Docetaxel With or Without Cetuximab in Treating Patients With Metastatic Pancreatic Cancer | View | |
| NCT00059020 | The Role of Gene Changes in Brain Tumor Formation and Growth | View | |
| NCT00346099 | Study of Panitumumab Given First With Capecitabine and Oxaliplatin CAPOX and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum | View | |
| NCT00350753 | Avastin and Tarceva for Upper Gastrointestinal Cancers | View | |
| NCT00452244 | Gefitinib With or Without Simvastatin in Non-Small Cell Lung Cancer NSCLC | View | |
| NCT00588445 | Phase II Trial to Correlate Radiographic Response Induced By Gefitinib With Mutations in the Protein-Tyrosine Kinase Domain of the EGF Receptor Gene | View | |
| NCT00598299 | Comparison of the Effects on Promoting Corneal Epithelial Wound Healing Between Human Auto-Serum and Cord Blood Serum | View | |
| NCT00681642 | Corneal Epithelial Wound Healing Difference Between Human Autoserum and Cord Blood Serum | View | |
| NCT00815971 | Mutations in the Epidermal Growth Factor ReceptorEGFR Gene in Non-Small Cell Lung Carcinoma NSCLC and the Relation to Response of Treatment With Erlotinib | View | |
| NCT02507817 | Correlation Between LIF Leukemia Inhibitory Factor Levels in Cord and Maternal Blood in Women Treated With Mg | View | |
| NCT02955290 | CIMAvax Vaccine Nivolumab and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer | View | |
| NCT03047863 | Therapeutic Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors | View | |
| NCT04153799 | Study of CXCR5 Modified EGFE Chimeric Antigen Receptor Autologous T Cells in EGFR- Positive Patients With Advanced Non-small Cell Lung Cancer | View |