Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
DKK1
Name:
dickkopf WNT signaling pathway inhibitor 1
Location:
10q21.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT00741377 | A Study to Assess BHQ880 in Combination With Zoledronic Acid in Relapsed or Refractory Myeloma Patients | View | |
| NCT02013154 | A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab | View | |
| NCT05761951 | Phase 2 Study Evaluating the Efficacy of the Combination of DKN-01 DKK1 Inhibitor Leap Therapeutics and Pembrolizumab in the Treatment of Advanced or Recurrent Endometrial Cancer | View | |
| NCT04329351 | Impact of PTFE-d Barrier Intentionally Exposed to Bucal Environment in Guided Bone Regeneration to Ridge Preservation | View | |
| NCT02708368 | SOPs for CKD-MBD-Biomarkers | View | |
| NCT01431872 | Systemic Dickkopf-related Protein 1 DKK1During Estrogen Level Changes in Post-menopausal Breast Cancer Patients Treated With Aromatase Inhibitors | View | |
| NCT01711671 | A Study of DKN-01 and LenalidomideDexamethasone in Patients With Relapsed or Refractory Multiple Myeloma | View | |
| NCT05480306 | Phase 2 Study of DKN-01 in Colorectal Cancer | View | |
| NCT02375880 | Study of DKN-01 and GemcitabineCisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder | View | |
| NCT03591614 | Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma | View | |
| NCT03395080 | A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or Carcinosarcoma | View | |
| NCT04363801 | A Study of DKN-01 in Combination With Tislelizumab Chemotherapy in Patients With Gastric or Gastroesophageal Cancer | View | |
| NCT04681248 | Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors | View | |
| NCT01302886 | Study of BHQ880 in Patients With High Risk Smoldering Multiple Myeloma | View | |
| NCT01337752 | Study in Patients With Untreated Multiple Myeloma and Renal Insufficiency | View | |
| NCT02212262 | Role of Osteocytes in Myeloma Bone Disease | View | |
| NCT03837353 | A Parallel Arm Phase 1b2a Study of DKN-01 as Monotherapy or in Combination With Docetaxel for the Treatment of Advanced Prostate Cancer With Elevated DKK1 | View |