Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
CHEK2
Name:
checkpoint kinase 2
Location:
22q12.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT04190667 | Homologous Recombination Deficiency Status in Epithelial Ovarian Cancer | View | |
| NCT04508803 | Combination of HX008 And Niraparib in GErm-line-mutAted Metastatic Breast Cancer | View | |
| NCT04712890 | Determination of Prevalence and Features of HRRm mCRPC ADAM | View | |
| NCT06033092 | Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion | View | |
| NCT02624973 | PErsonalized TREatment of High-risk MAmmary Cancer - the PETREMAC Trial | View | |
| NCT03040791 | Nivolumab in Prostate Cancer With DNA Repair Defects ImmunoProst Trial | View | |
| NCT02401347 | Phase II Trial of Talazoparib in BRCA12 Wild-type HER2-negative Breast Cancer and Other Solid Tumors | View | |
| NCT05011383 | High Dose Testosterone for ATM CDK12 or CHEK2 Altered Prostate Cancers | View | |
| NCT05033756 | Comprehensive Analysis of Predictors of the Treatment With Pembrolizumab and Olaparib in Patients With Unresectable or Metastatic HER2 Negative Breast Cancer and a Deleterious Germline Mutation or a Homologous Recombination Deficiency COMPRENDO | View | |
| NCT05097274 | The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation | View | |
| NCT03012321 | AbirateronePrednisone Olaparib or AbirateronePrednisone Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects | View | |
| NCT06177171 | Olaparib and ASTX727 in BRCA12- and Homologous Recombination Deficient HRD-Mutated Tumors | View | |
| NCT06392841 | Niraparib Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations | View | |
| NCT03786796 | Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations | View | |
| NCT04254133 | Genetic Information to Inform Treatment and Screening for Prostate Cancer GIFTS Study | View | |
| NCT04265937 | ScreenIng of Genetic Susceptibility Genes for Breast Cancer Patients in CHinese communiTies | View | |
| NCT05787587 | A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors | View | |
| NCT02952534 | A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency | View |