Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
XIAP
Name:
X-linked inhibitor of apoptosis
Location:
Xq25
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT00773747 | Study of Vorinostat MK-0683 or Placebo in Combination With Bortezomib in Participants With Multiple Myeloma MK-0683-088 AMN | View | |
| NCT00363974 | Study of XIAP Antisense Given With Chemotherapy for RefractoryRelapsed AML | View | |
| NCT00385775 | Study of XIAP Antisense for Advanced Cancers | View | |
| NCT00558922 | A Phase 1-2 XIAP Antisense AEG35156 With Carboplatin and Paclitaxel in Patients With Advanced Non-Small Cell Lung Cancer | View | |
| NCT00558545 | A Phase 1-2 XIAP Antisense AEG35156 With Weekly Paclitaxel in Patients With Advanced Breast Cancer | View | |
| NCT00768339 | A Phase 1-2 Multicenter Open-Label Study of AEG35156 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas | View | |
| NCT00882869 | XIAP Antisense AEG35156 in Combination With Sorafenib in Patients With Advanced Hepatocellular Carcinoma HCC | View | |
| NCT01018069 | AEG35156 in Combination With High-dose Cytarabine and Idarubicin in AML Following Failure of a Single Standard Dose Cytarabine Based Frontline Induction Regimen | View | |
| NCT05082259 | ASTEROID A Trial of ASTX660 in Combination With Pembrolizumab | View | |
| NCT04641442 | Study to Evaluate the Efficacy Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases Including NLRC4-GOF XIAP Deficiency or CDC42 Mutations | View | |
| NCT03512314 | Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency as Open Label Extension | View | |
| NCT04155580 | A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With RelapsedRefractory Acute Myeloid Leukemia AML | View | |
| NCT06309823 | A Single-patient Clinical Trial of MAS825 in a Patient With XIAP Deficiency | View | |
| NCT06590558 | Testing the Addition of an Investigational Anti-Cancer Drug ASTX660 Tolinapant to a Usual Chemotherapy Treatment Eribulin for Treatment of Advanced Triple Negative Breast Cancer | View | |
| NCT06393751 | Testing the Addition of ASTX660 Tolinapant to the Usual Chemotherapy Treatment Paclitaxel With or Without Bevacizumab in Patients With Recurrent Ovarian Cancer | View | |
| NCT02909244 | Study of Gut Microbiota in Primary Immune Deficiency Possibly Associated With Inflammatory Bowel Disease | View | |
| NCT00557596 | A Phase 1-2 XIAP Antisense AEG35156 With Gemcitabine in Patients With Advanced Pancreatic Cancer | View | |
| NCT03113760 | Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency | View |