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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: VWF
Name: von Willebrand factor
Location: 12p13.31
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all

Clinical Studies

NCT Number Status Brief Title View
NCT00426686 ADAMTS13 in Thrombotic Thrombocytopenic Purpura View
NCT00701610 Levels of Von Willebrand Factor Multimers and VWF-Cleaving Protease ADAMTS-13 in Preterm and Neonate View
NCT00773539 A Prospective Randomized Study Comparing Radiofrequency Energy With Cryoenergy View
NCT00937131 The Use of Rituximab in Acute Thrombotic Thrombocytopenic Purpura TTP View
NCT02245633 Correlation Between Vitamin D Levels to ADAMTS13 VWF and Micro RNA Expression in Diabetic Hemodialysis Patients View
NCT03065751 Plasmaexchange in Early Septic Shock View
NCT03167320 Low Von Willebrand in Ireland Cohort Study View
NCT04267406 ADAMTS-13 and Von Willebrand Factor Levels and Activities in Children With Cirrhosis andor Portal Hypertension View
NCT03728049 Von Willebrand Factor Point-of-care Testing to Improve Minimally Invasive TAVI Outcomes View
NCT04106908 Effectiveness and Tolerability of Eqwilate in Real-life Conditions View
NCT04231994 Therapeutic Plasmaexchange in Early Septic Shock View
NCT04303936 PHYSICAL ACTIVITY AND FVIII CLEARANCE RELEVANCE FOR PERSONALIZED THERAPY IN SEVERE HAEMOPHILIA A PHYSEMO View
NCT04344860 Prevent Postpartum Hemorrhage in Women With Von Willebrand Disease The VWD-WOMAN Trial View
NCT04456894 Primary Hemostasis Pathology in Patients on ECMO During Lung Transplantation View
NCT04677803 BT200 in Hereditary Bleeding Disorders View
NCT04812054 Dual Hypothermic Oxygenated Machine Perfusion in Liver Transplantation Using Allografts From Donors After Brain Death View
NCT01051076 Rescue Immunotolerance Study in Induction of Immune Tolerance ITI-Experienced Patients RESIST Experienced View
NCT05116501 Genetic Background of Patients With Low Von Willebrand Factor Levels View
NCT05628558 Genetic Influence of Genetic Factors Influencing the Desmopressins Efficacy in MildModerate Hemophilia A View
NCT06020456 Genetic Factors of the Desmopressin Response in Carriers of Hemophilia A View
NCT02466789 Investigating a Von Willebrand Factor VWF Functional Screening Assay for Assigning the Phenotypic Variants of Von Willebrand Disease VWD View
NCT04319341 Obstetric Antiphospholipid Antibody Syndrome Contribution of the Evaluation of ADAMTS13 Made at the Diagnosis of Pregnancy on Evaluation the Risk of Pre-eclampsia View
NCT01151423 Study to Assess Efficacy and Safety of Anti-von Willebrand Factor vWF Nanobody in Patients With Acquired Thrombotic Thrombocytopenic Purpura aTTP View
NCT03379974 Exercise Versus DDAVP in Patients With Mild Hemophilia A View
NCT02812953 Biological Collection and Registry of Patients Who Will Have a TAVR Transcatheter Aortic Valve Replacement Intervention View
NCT00151125 Phase II Study of IL-11 Neumega in Von Willebrand Disease View
NCT01358123 Value of Von Willebrand Factor in Portal Hypertension View
NCT04466878 Prognostic Value of Implementing VCE on Top in Constitutional VWD-patients With GI-bleeding View
NCT01800526 A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease View
NCT02756429 Quantification of Endothelial Thrombogenicity in Patients With Atrial Fibrillation View
NCT00613496 Irbesartan and Adhesion Molecules in AF View
NCT02250508 A Study to Compare the Pharmacokinetics and Safety of Optivate and Haemate P in Patients With Von Willebrand Disease View
NCT02552576 Study of Voncento in Subjects With Von Willebrand Disease View
NCT01213446 Study of Biostate in Children With Von Willebrand Disease View
NCT04759131 Safety Efficacy and PK of BIVV001 in Pediatric Patients With Hemophilia A View
NCT04770935 To Assess the Pharmacokinetics and Safety and Tolerability of Efanesoctocog Alfa BIVV001in Adults With Type 2N and 3 Von Willebrand Disease VWD View
NCT02460458 Type 3 Von Willebrand International Registries Inhibitor Prospective Study View
NCT02933411 Low VW Activity in Adolescent HMB View
NCT03136003 DDAVP vs Exercise in Patients With Mild Hemophilia A View
NCT01808521 A Pilot Study of N-acetylcysteine in Thrombotic Thrombocytopenia Purpura View
NCT02118545 Von Willebrand Factor to Predict Postoperative Outcome View
NCT03715673 Von Willebrand Antigen and Activity as Novel Biomarkers of Hemostasis in Inflammatory Bowel Disease View
NCT05688306 To Evaluate Thrombosis Risk in Chemotherapy Patients With Solid Tumors Who Receiving Thrombocytopenia Treatment View
NCT03613584 Von Willebrand Factor Concentrate During ECMO Support View
NCT05752565 Physical Activity and FVIII Elimination Relevance to Personalized Therapy in Severe Hemophilia A View
NCT01224808 Extension Study of Biostate in Subjects With Von Willebrand Disease View
NCT03861286 Haemostatic Markers in Cardiopulmonary Bypass View
NCT04317469 Evaluation of Von Willebrand Factor as a Marker For Early Diagnosis of Acute Respiratory Distress Syndrome ARDS in Comparison to Interleukin 6 IL-6 View
NCT04553172 Vascular Abnormalities and Bleeding Diathesis View
NCT03136510 Evolution of Coagulation Activity in Non Valvular Atrial Fibrillation Patients Under Apixaban View
NCT04391374 Hemostatic Endothelial Dysfunction in Patients With Peripheral Artery Disease View
NCT03204539 INdividualized ITI Based on FviiiATE Protection by VWF View
NCT03205163 A Safety Tolerability and Pharmacokinetics Study of a Single Intravenous Injection of Recombinant Coagulation Factor VIII Fc - Von Willebrand Factor - XTEN Fusion Protein rFVIIIFc-VWF-XTEN BIVV001 in Previously Treated Adults With Severe Hemophilia A EXTEN-A View
NCT03896997 Update in VWD Laboratory Diagnosis View
NCT04644575 Long-term Safety and Efficacy of Efanesoctocog Alfa BIVV001 in Previously Treated Patients With Hemophilia A View
NCT03853486 ATHN 9 Severe VWD Natural History Study View
NCT03966313 Perioperative Modification of Hemostasis During Ventricular Assist Device Implantation View
NCT04324255 Von Willebrand Factor and Protein C Ratio in Graft Function After Liver Transplant View
NCT04657887 Registry of Patients With Von WilLEbrand Disease Treated With Voncento View
NCT05876221 Platelet Response to Caplacizumab in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura View
NCT06050993 Effects of Platelet Mimicking Nanoparticles in Patients With Cirrhosis View
NCT04849338 The Role of Standardized Bleeding Score in Diagnosis of Pediatric Von Willebrands Disease View
NCT05015244 Impact of Von Willebrand Factor-platelet Aggregates in Patients With Type 2B Disease View
NCT05550896 Platelet Adhesion in the Pathobiology of Aortic Stenosis View
NCT05582993 A Study of Recombinant Von Willebrand Factor rVWF TAK-577 in Children With Severe Von Willebrand Disease vWD View
NCT00941616 Study of a pd VWFFVIII Concentrate Biostate in Subjects With Von Willebrand Disease View
NCT00994929 Efficacy and Safety of IL-11 in DDAVP Unresponsive View
NCT06066814 To Study the Role of Plasma Von Willebrand Factor Antigen vWF to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 ADAMTS-13 Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure ACLF Patients View
NCT06118372 Recombinant VWF Concentrate and ECMO View
NCT00156520 Platelet Function And Aggregometry In Patients With Aortic Valve Stenosis View
NCT06367166 Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins View
NCT05500807 Emicizumab for Severe Von Willebrand Disease VWD and VWDHemophilia A View
NCT04103034 A SADMAD Study of Safety Tolerability and Pharmacologic Activity of BT200 in Normal Volunteers View
NCT01505946 Thrombin Generation Assay TGA as Predictive Test for Haemostatic Effectiveness of FVIII Concentrates in Haemophiliac A With Inhibitors View
NCT04146376 Von Willebrand Factor in Pregnancy VIP Study View
NCT02219035 A Prospective Investigation of the VWF-ADAMTS 13 Axis in Acute Ischaemic Brain Injury TIAs and Stroke View
NCT01425775 The Effect of Vitamin D Supplementation on Disease Activity Markers in Systemic Lupus Erythematosus SLE View
NCT02792205 Performance Evaluation of Von WillebrandCollagen-Binding Assays to Diagnose Von Willebrand Factor Deficiency in Patients With Increased Risk of Bleeding View
NCT04161495 A Phase 3 Open-label Interventional Study of Intravenous Recombinant Coagulation Factor VIII Fc-von Willebrand Factor-XTEN Fusion Protein Efanesoctocog Alfa BIVV001 in Patients With Severe Hemophilia A View
NCT00580424 The Effect of the Mini-pill on Blood Factors in Women at Increased Risk for Forming Blood Clots View
NCT02488525 Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support View
NCT02506023 Characterization of Laboratory Response to DDAVP in Adult Hemophilia A Carriers View
NCT02869074 Molecular and Clinical Profile of Von Willebrand Disease in Spain View
NCT03237819 Magnesium Sulfate in Thrombotic Thrombocytopenic Purpura in Intensive Care View
NCT03875924 REAL-LIFE DATA OF CONSTITUTIONAL VON WILLEBRAND DISEASE IN WESTERN FRANCE HOPSCOTcH-WILL View
NCT04053699 Bleeding Incidence in VWD Patients Undergoing On-Demand Treatment View