Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
SIRT1
Name:
sirtuin 1
Location:
10q21.3
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT04184323 | SIRT-1 Antagonism for Endometrial Receptivity | View | |
| NCT01508091 | Calorie Restriction Retards the Aging Process | View | |
| NCT02633150 | Assessing the Value of Red Grapes Polyphenol Supplementation on Metabolic Parameters in Obese Insulinoresistant Subjects | View | |
| NCT01018628 | A Clinical Study to Assess the Safety and Pharmacokinetics of SRT2379 in Normal Healthy Male Volunteers | View | |
| NCT01031108 | A Clinical Trial to Assess the Safety of Oral SRT2104 and Its Effects on Vascular Dysfunction in Otherwise Healthy Cigarette Smokers and Subjects With Type 2 Diabetes Mellitus | View | |
| NCT03934905 | Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction | View | |
| NCT04433273 | Electrical Vestibular Stimulation VeNS Assessment of AMPK SIRT1 Following Repeated Usage | View | |
| NCT05160844 | SIRT1 Gene Polymorphism With Premature Myocardial Infarction in Young Egyptian Patients | View | |
| NCT03554941 | Non Invasive Vestibular Stimulation in Modulation of Vestibular and Balance Function | View | |
| NCT05877235 | Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin | View | |
| NCT03610321 | Lipid-lowering Effects of Gefarnate in Statin-treated Coronary Heart Disease Patients With Residual Hypertriglyceridemia | View | |
| NCT01150955 | Potential Beneficial Effects of Resveratrol | View | |
| NCT03393377 | Preventive Arterial Wall Phenotype and Low-dose FluvastatinValsartan Combination | View | |
| NCT01668836 | Influence of Caloric Restriction and Resveratrol in the Sirtuin System in Women and Men Aged 55 to 65 Years | View | |
| NCT00978640 | Sirtuin Mediated Effects of 36 Hour Fast and 1 Hour Exercise | View | |
| NCT01677611 | Effects of Resveratrol in Patients With Type 2 Diabetes | View | |
| NCT01014117 | Effect of SRT2104 on Endotoxin-induced Inflammation | View | |
| NCT01209429 | Importance of the GHIGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction | View | |
| NCT04767841 | The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis | View | |
| NCT01262911 | Effect of SRT2379 on Endotoxin-Induced Inflammation | View | |
| NCT01765946 | Metformin and Longevity Genes in Prediabetes | View | |
| NCT01416376 | Effect of Multiple Dose Levels of SRT2379 on Endotoxin-Induced Inflammation | View | |
| NCT01938521 | Effects of Red Grape Cells RGC Powder in Type 2 Diabetics | View | |
| NCT05488652 | Cerebromicrovascular Effects of Time-Restricted Eating in Older Adults | View | |
| NCT02463318 | The Effect of Melatonin on Gene Expression and Activity of the Sirt1 and Its Target Genes Catalase and MnSOD in Multiple Sclerosis Patients and Healthy Subjects | View | |
| NCT03557983 | Evaluation of Fenofibrate on Radiation-induced Skin Injury | View | |
| NCT06055634 | SIRT1rs7069102 Gene Polymorphism in Chronic Obstructive Pulmonary Disease at Egyptian Patients | View | |
| NCT03384329 | Efficacy of Resveratrol in Depression | View | |
| NCT03535441 | HMGB1 Release From Hemorrhagic Shock Patients | View | |
| NCT03925714 | Impact of P53 and SIRT1 in Type 2 Diabetes | View | |
| NCT05040321 | Sirtuin-NAD Activator in Alzheimers Disease | View | |
| NCT02388854 | Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis a Case Control Study of the Sardinian Population | View | |
| NCT04405895 | Effect of Meal Timing in T2D on Hepatocytes SRIT1 and Clock Genes | View | |
| NCT06036355 | The Exploratory Study on the Biological Function of Dendritic Cells In Vivo Supported by Nicotinamide Mononucleotide Vital NAD | View | |
| NCT06351722 | Non-surgical Periodontal Treatment in Smokers on SIRT-1 NLRP3 Inflammasome and LncRNAs | View | |
| NCT06635369 | Taurine in Periodontitis and Aging | View | |
| NCT05988346 | Ghrelin and Diastolic Heart Function | View | |
| NCT06019195 | The Effect of Intermittent Fasting on Brain Health | View | |
| NCT02549924 | Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus | View | |
| NCT02102971 | Observational Study of Biomarker During Liver Surgery | View | |
| NCT03943459 | Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease | View | |
| NCT02783196 | Effect of Liraglutide on Clock Genes | View | |
| NCT00654667 | Mechanisms of Metabolic Regulation of Resveratrol on Humans With Metabolic Syndrome | View | |
| NCT03819517 | Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease | View | |
| NCT04039204 | Elagolix for Fertility Enhancement Clinical Trial | View | |
| NCT04107129 | Predicting Endometrial Receptivity for Optimal Reproductive Management | View | |
| NCT04137406 | Role of SIRT1 in Regulation of Epithelial-to-mesenchymal Transition in Breast Cancer Lymph Nodes Metastasis | View |