Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
PRMT5
Name:
protein arginine methyltransferase 5
Location:
14q11.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT03886831 | A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies | View | |
| NCT04676516 | A Phase II Window of Opportunity Trial of PRMT5 Inhibitor GSK3326595 in Early Stage Breast Cancer | View | |
| NCT05528055 | A Study to Investigate the Safety and Tolerability of SCR-6920 Capsule in Patients With Advanced Malignant Tumors | View | |
| NCT06333951 | AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion Master Protocol | View | |
| NCT03854227 | A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors | View | |
| NCT04089449 | A Study of PRT811 in Participants With Advanced Solid Tumors CNS Lymphoma and Gliomas | View | |
| NCT04794699 | Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion | View | |
| NCT06130553 | A Study of AZD3470 a PRMT5 Inhibitor in Patients With MTAP Deficient AdvancedMetastatic Solid Tumours | View | |
| NCT06360354 | A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal Biliary Tract or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase MTAP-Deletion | View | |
| NCT05245500 | Phase 12 Study of MRTX1719 in Solid Tumors With MTAP Deletion | View | |
| NCT05732831 | Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors | View | |
| NCT06589596 | An Investigational Study of BGB-58067 in Participants With Advanced Solid Tumors | View | |
| NCT06137144 | AZD3470 as Monotherapy and in Combination With Anticancer Agents in Participants With RelapsedRefractory Haematologic Malignancies | View | |
| NCT06188702 | S095035 in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of the Methylthioadenosine Phosphorylase MTAP Gene | View | |
| NCT05275478 | Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors | View | |
| NCT03573310 | A Study of JNJ-64619178 an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors NHL and Lower Risk MDS | View |