Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
NF2
Name:
NF2 moesin-ezrin-radixin like (MERLIN) tumor suppressor
Location:
22q12.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT00598351 | Natural History Study of Patients With Neurofibromatosis Type 2 | View | |
| NCT01222728 | Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients | View | |
| NCT00973739 | Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 NF2 and NF2-Related Tumors | View | |
| NCT01419639 | Phase II Study of Everolimus RAD001 in Children and Adults With Neurofibromatosis Type 2 | View | |
| NCT01864291 | Auditory Brainstem Implant ABI in Pediatric Non-Neurofibromatosis Type 2 Subjects | View | |
| NCT00340496 | Analysis of NF2 Mutations in Radiation-Related Neural Tumors | View | |
| NCT02831257 | AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas | View | |
| NCT04857372 | A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors | View | |
| NCT05130866 | Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 NF2 Mutated Meningiomas | View | |
| NCT01207687 | Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 NF2 | View | |
| NCT01490476 | Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannomas in Neurofibromatosis 2 NF2 Patients | View | |
| NCT01850225 | Feasibility Study of Auditory Brainstem Implant in Young Children | View | |
| NCT02352844 | Everolimus in Patients With Advanced Solid Malignancies With TSC1 TSC2 NF1 NF2 or STK11 Mutations | View | |
| NCT03095248 | Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors | View | |
| NCT01345136 | Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma | View | |
| NCT01736267 | Auditory Brainstem Implant ABI in Adult Non-Neurofibromatosis Type 2 Subjects | View | |
| NCT01885767 | Neurofibromatosis NF Registry Portal | View | |
| NCT02102256 | A Safety Study of the Auditory Brainstem Implant for Pediatric Profoundly Deaf Patients | View | |
| NCT02104323 | Endostatin Study for Patients With Neurofibromatosis Type 2 NF2 and NF2-Related Tumors | View | |
| NCT02129647 | Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas | View | |
| NCT02246231 | Effect of Implant Position on Magnetic Resonance Image Distortion | View | |
| NCT02282917 | Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma | View | |
| NCT02298270 | Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype | View | |
| NCT02310399 | Auditory Brainstem Implant ABI in Children With No Cochleae or Auditory Nerves | View | |
| NCT02435628 | Relationship Between Psychosocial Factors Health Literacy Quality of Life and Satisfaction With Medical Visits in Adults With NF | View | |
| NCT02589912 | Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients | View | |
| NCT05821790 | Role of the Tumor Microenvironment in Aggressive Meningiomas | View | |
| NCT02934256 | Icotinib Study for Patients With Neurofibromatosis Type 2 NF2 and NF2-Related Tumors | View | |
| NCT02984202 | Auditory Midbrain Implant Study | View | |
| NCT04374305 | Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis INTUITT-NF2 | View | |
| NCT03617276 | Reliability of Functional Outcome Measures in Neurofibromatosis 2 | View | |
| NCT03873610 | Resiliency Training in Adolescents With NF1 and NF2 | View | |
| NCT05685836 | 89Zr-Bevacizumab PETCT Imaging in NF2 Patients | View | |
| NCT04283669 | Phase 2 Clinical Trial of Crizotinib for Children and Adults with Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas | View | |
| NCT04439331 | Testing VS-6063 Defactinib as a Potential Targeted Treatment in Cancers With NF2 Genetic Changes MATCH-Subprotocol U | View | |
| NCT04665206 | Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors Enriched for Tumors With NF2 or mNF2 Gene Mutations | View | |
| NCT05228015 | Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors | View | |
| NCT06553365 | Phase II Study of FCN-159 in NF2 Nerve Sheath Tumors | View | |
| NCT05521048 | Doxycycline in Cutaneous Schwannoma NF2 | View | |
| NCT00863122 | Concentration and Activity of Lapatinib in Vestibular Schwannomas | View | |
| NCT01776125 | Genetic Evaluation of NF1 and Scoliosis Patients | View | |
| NCT00004483 | NF2 Natural History Consortium | View | |
| NCT00911248 | PTC299 for Treatment of Neurofibromatosis Type 2 | View | |
| NCT02811718 | Resiliency Training for Patients With NF2 Via Videoconferencing With Skype | View | |
| NCT03210285 | WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data | View | |
| NCT03672838 | A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 NF1 and Type 2 NF2 | View |