Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
MTOR
Name:
mechanistic target of rapamycin kinase
Location:
01p36.22
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT00948883 | Study of Cancers After Solid Organs Transplants | View | |
| NCT01690871 | A Phase II Study of Orally Administered BEZ235 Monotherapy in Patients With Metastatic or Unresectable Malignant PEComa | View | |
| NCT00409994 | Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer | View | |
| NCT00459186 | The Use of RAD001 With Docetaxel in the Treatment of Metastatic Androgen Independent Prostate Cancer | View | |
| NCT00490789 | Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM | View | |
| NCT00491517 | Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease Renal Efficacy and Safety | View | |
| NCT00529802 | Exploratory Study Evaluating Fluorodeoxyglucose - Position Emission Tomography as a Predictive Marker for Therapy With RAD001 in Metastatic Renal Cell Cancer | View | |
| NCT00567554 | Bevacizumab Everolimus RAD001 and Lapatinib as Neoadjuvant Chemotherapy Regimes for Primary Breast Cancer | View | |
| NCT00636090 | Molecular Genetic and Genomic Assessments From Patients Treated With RAD001 | View | |
| NCT00703170 | Phase I Study of DOXIL and Temsirolimus in Resistant Solid Malignancies | View | |
| NCT00926107 | Study of the mTOR Inhibitor Temsirolimus CCI-779 to Treat Ovarian Cancer With CA125 Only Relapse | View | |
| NCT01047293 | RAD001 FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma | View | |
| NCT01096199 | A Study of TS-1 Cisplatin CDDP and RAD001 Everolimus | View | |
| NCT01122199 | Study of RAD001 AMG479 for Patients With Advanced Solid Tumors | View | |
| NCT01206764 | A Trial of Everolimis in Patients With Advanced Renal Cell Carcinoma | View | |
| NCT01265030 | A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis | View | |
| NCT01271270 | Palomid 529 in Patients With Neovascular Age-Related Macular Degeneration | View | |
| NCT01290406 | BEZ235 Trial in Patients With Advanced Endometrial Carcinoma | View | |
| NCT01412892 | Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas | View | |
| NCT01467986 | Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma | View | |
| NCT01470209 | A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies | View | |
| NCT01582191 | Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer | View | |
| NCT00985374 | A Multiple Ascending Dose Study of the mTOR Inhibitor RAD001 in Combination With R1507 in Patients With Advanced Solid Tumors | View | |
| NCT01620593 | Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate Cancer | View | |
| NCT01687361 | Can Branched Chain Amino Acids Supplementation Reduce Muscle Damage Induced by Neuromuscular Electrical Stimulation A Combined Functional and Metabolic Non-invasive Investigation in Healthy Humans | View | |
| NCT01684449 | Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma | View | |
| NCT01707849 | The Impact of Everolimus Based Immunosuppression in the Evolution of Hepatitis C Fibrosis After Liver Transplantation | View | |
| NCT01796028 | Metformin-Docetaxel Association in Metastatic Hormone-refractory Prostate Cancer | View | |
| NCT01805271 | Safety Study of Adding Everolimus to Adjuvant Hormone Therapy in Women With High Risk of Relapse ER and HER2- Primary Breast Cancer Free of Disease After Receiving at Least One Year of Adjuvant Hormone Therapy | View | |
| NCT00996346 | Phase III Study of Irinotecan and Temsirolimus in Patients With Refractory Sarcomas | View | |
| NCT01962896 | A Phase II Study of Sirolimus and Erlotinib in RecurrentRefractory Germ Cell Tumors | View | |
| NCT02019693 | A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer | View | |
| NCT02062944 | SRL Sirolimus Withdrawal | View | |
| NCT02093598 | POEM STUDY A Phase IIa Trial in Endometrial Carcinoma With Temsirolimus | View | |
| NCT02294006 | Activity and Safety of EverolimusOctreotide LARMetformin in Advanced Pancreatic Well-differentiated NETs | View | |
| NCT02315625 | Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery | View | |
| NCT02325505 | Characterization of Patients With Tuberous Sclerosis Complex Lymphangioleiomyomatosis and Angiomyolipoma | View | |
| NCT03504098 | Folate One-carbon Malnutrition as the Metabostemness Risk Factor of Malignancy Tumor Development of NSCLC Patients | View | |
| NCT02616848 | Safety and Tolerability of Everolimus in Combination With Eribulin in Triple-negative Breast Cancers | View | |
| NCT02503566 | Assessment of Cardiac Allograft Vasculopathy by Optical Coherence Tomography | View | |
| NCT02509468 | suPERficial Slow-flow Vascular malFORMations Treated With sirolimUS | View | |
| NCT01009203 | Temsirolimus Torisel and Erlotinib Tarceva in Platinum-RefractoryIneligible Advanced Squamous Cell Carcinoma | View | |
| NCT02561481 | Sulforaphane Treatment of Children With Autism Spectrum Disorder ASD | View | |
| NCT00113360 | RAD001 Plus Octreotide Depot in Metastatic or Unresectable Low Grade Neuroendocrine Carcinoma | View | |
| NCT04894240 | A Study of Monepantel in Individuals With Motor Neurone Disease | View | |
| NCT02773771 | Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit | View | |
| NCT02849899 | Prevention of Diabetes After Transplantation by Vildagliptin in the Early Post-transplant Period | View | |
| NCT03685448 | ANZUP - Non-clear Cell Post Immunotherapy CABozantinib UNICAB | View | |
| NCT02983058 | PET Imaging Study of Amish and Mennonite Patients With CNTNAP2 Mutations | View | |
| NCT03097601 | ELRCXCL Cytokines in Metastatic Kidney Cancers Predictive Markers of Resistance to Sunitinib | View | |
| NCT03115164 | Astrocytoma Desmoplastic Gamliogliomes DIA DIG - Study of the French Cohort of the Last 20 Years Clinical Anatomopathological Molecular and Radiological Charactersics | View | |
| NCT03161340 | Immunomodulatory Effects of Rapamycin on Pregnancy Rate of Patient With Recurrent Implantation Failure | View | |
| NCT03168880 | A Randomized Controlled Trial of Neoadjuvant Weekly Paclitaxel Versus Weekly Paclitaxel Plus Weekly Carboplatin In Women With Large Operable or Locally Advanced Triple Negative Breast Cancer | View | |
| NCT03216967 | Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia | View | |
| NCT01020305 | Temsirolimus to Reverse Androgen Insensitivity for Castration-resistant Prostate Cancer | View | |
| NCT03290092 | Trial of Taselisib in Overgrowth | View | |
| NCT01210911 | Metformin Combined With Chemotherapy for Pancreatic Cancer | View | |
| NCT00703625 | Phase I Study of Docetaxel and Temsirolimus in Resistant Solid Malignancies | View | |
| NCT03631953 | Combination of Alpelisib and Trametinib in Progressive Refractory Meningiomas | View | |
| NCT03662412 | Study of Sirolimus in Patients With Advanced Pancreatic Cancer | View | |
| NCT03664115 | Itraconazole in Non Small Cell Lung Cancer | View | |
| NCT03669692 | Open Randomized Clinical Trial to Evaluate the Effects of Intermittent Caloric Restriction in Patients With Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia | View | |
| NCT03730428 | Everolimus Related Pneumonitis in MBC | View | |
| NCT03745911 | Paclitaxel and TAK-228 in Urothelial Carcinoma | View | |
| NCT03743675 | Influence of Aerobic Training and Weight Loss on Skeletal Muscle Inflammatory Markers and Muscle Protein Balance in Older Adults | View | |
| NCT03764605 | Metformin vs Tolvaptan for Treatment of Autosomal Dominant Polycystic Kidney Disease | View | |
| NCT00657982 | Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate Cancer | View | |
| NCT05241561 | Cabo-POLARIS A Trial to Evaluate Cabozantinib Among Haemodialysied Patients | View | |
| NCT00604357 | CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment | View | |
| NCT05144698 | RAPA-201 Therapy of Solid Tumors | View | |
| NCT04928963 | Fighting Immunosenescence and Promoting Immunity by a Fasting-mimicking Diet Elderly | View | |
| NCT05743686 | App for Adverse Events to Oral Chemotherapy - Pilot Study | View | |
| NCT04993872 | Pharmacokinetics of Calcineurin mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BICFTCTAF | View | |
| NCT05166499 | HMB Enriched Amino Acids to Reverse Muscle Loss in Cirrhosis | View | |
| NCT05190627 | Effect of Loratadine in Lymphangioleiomyomatosis | View | |
| NCT05235464 | High Protein Diet and Atherosclerosis | View | |
| NCT05237687 | The Role of Sirolimus in Preventing Functional Decline in Older Adults | View | |
| NCT01079286 | Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers | View | |
| NCT02102893 | Gastroenteral-Pancreatic Neuroendocrine Tumors in Taiwan | View | |
| NCT05495425 | Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC | View | |
| NCT01088893 | Everolimus in Breast Cancer Patients After Pre-operative Chemotherapy | View | |
| NCT02566590 | Preventing the Loss of Muscle and Function in Hospitalized Older Adults | View | |
| NCT05663944 | REpurposing SirolimUS in Compensated Advanced Chronic Liver Disease the RESUS Proof of Concept Study | View | |
| NCT01087554 | Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer | View | |
| NCT01088048 | Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody mAb in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkins Lymphoma Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia | View | |
| NCT01082068 | Study of XL147 SAR245408 or XL765 SAR245409 in Combination With Letrozole in Subjects With Breast Cancer | View | |
| NCT00079235 | CCI-779 in Treating Patients With Stage IIIB With Pleural Effusion or Stage IV Non-Small Cell Lung Cancer | View | |
| NCT02619669 | Neoadjuvant Run-In Study With TAK-228 Followed by LetrozoleTAK-228 in Women With High-Risk ERHER2- Breast Cancer | View | |
| NCT00390195 | Randomized Phase III of RAD001 in Advanced Hepatocellular Carcinoma HCC | View | |
| NCT00331409 | Everolimus and Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Kidney Cancer | View | |
| NCT03208868 | Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis | View | |
| NCT02338401 | Fish Oil Supplementation Resting Energy Expenditure Skeletal Muscle Membrane Composition and Metabolism in Elderly Subjects | View | |
| NCT03610321 | Lipid-lowering Effects of Gefarnate in Statin-treated Coronary Heart Disease Patients With Residual Hypertriglyceridemia | View | |
| NCT01152801 | Safety of RAD001 in Chinese Patients With Metastatic Renal Cell Cancer | View | |
| NCT01175096 | Safety and Tolerability Profile of RAD001 Daily in Chinese Patients With Advanced Pulmonary Neuroendocrine Tumor | View | |
| NCT01420081 | A Study Of Two Dual PI3KmTOR Inhibitors PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial Cancer | View | |
| NCT00086125 | Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies 8669-024COMPLETED | View | |
| NCT01188889 | RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w Molecular Disease | View | |
| NCT01184885 | A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy | View | |
| NCT01234857 | A Study of Ridaforolimus MK-8669 in Combination With Dalotuzumab MK-0646 Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients MK-8669-041 AM3 | View | |
| NCT00473005 | Phase I Oral mTOR Inhibitor RAD001 in Combo w Capecitabine for Metastatic Breast | View | |
| NCT00060632 | Safety Study of Ridaforolimus in Patients With Advanced Refractory or Recurrent Malignancies MK-8669-001 AM5COMPLETED | View | |
| NCT01276834 | Comparison of Immunosuppression on Progression of Arteriosclerosis in Renal Transplantation | View | |
| NCT00093080 | Study of AP23573MK-8669 Ridaforolimus A Mammalian Target of Rapamycin mTOR Inhibitor in Participants With Advanced Sarcoma MK-8669-018 AM1COMPLETED | View | |
| NCT01289301 | Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant | View | |
| NCT01282697 | Clinical Trial of Rapamycin and Irinotecan in Pediatric Patients With Refractory Solid Tumors | View | |
| NCT00499603 | Paclitaxel Followed by FEC Versus Paclitaxel and RAD001 Followed by FEC In Women With Breast Cancer | View | |
| NCT01298713 | Tamoxifen-RAD001 Versus Tamoxifen Alone in Patients With Anti-aromatase Resistant Breast Metastatic Cancer | View | |
| NCT01316809 | AZD8055 for Adults With Recurrent Gliomas | View | |
| NCT02332902 | Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis1 CRAD001CUS232T | View | |
| NCT00510068 | Efficacy and Safety of Everolimus RAD001 Compared to Placebo in Patients With Advanced Neuroendocrine Tumors | View | |
| NCT01152840 | Study of RAD001 in Adenoid Cystic Carcinoma | View | |
| NCT01347866 | Clinical Study Of PI3KmTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer | View | |
| NCT01347554 | Efficacy of Everolimus-Eluting Versus Zotarolimus-Eluting Sten for Coronary Lesions in Acute Myocardial Infarction | View | |
| NCT00355862 | Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma | View | |
| NCT00352950 | Safety Evaluation of Panitumumab and Sirolimus in Advanced Non-Small Cell Lung Cancer | View | |
| NCT00353301 | Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma | View | |
| NCT00378703 | Bevacizumab Sorafenib Tosylate and Temsirolimus in Treating Patients With Metastatic Kidney Cancer | View | |
| NCT01414660 | Evolution of Interleukin 7 Fat Mass and Metabolic Profile Before and After Transplantation | View | |
| NCT00414648 | Efficacy and Safety of Sirolimus in LAM | View | |
| NCT01430572 | Pazopanib and Everolimus in PI3KCA Mutation PositivePTEN Loss Patients | View | |
| NCT00457964 | RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM | View | |
| NCT01449955 | Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory | View | |
| NCT00485719 | Study of the Safety and Pharmacokinetics of XL765 SAR245409 in Adults With Solid Tumors | View | |
| NCT01461603 | Local Effects of Amino Acids and 3-hydroxybutyrate in the Bilaterally Perfused Human Leg | View | |
| NCT01920061 | A Study Of PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm TNBC | View | |
| NCT01473095 | Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma | View | |
| NCT01471847 | A Phase IbII Study of BEZ235 and Trastuzumab in Patients With HER2-positive Breast Cancer Who Failed Prior to Trastuzumab | View | |
| NCT01477060 | Modulation of Response to Hormonal Therapy With Lapatinib andor Metformin in Patients With Metastatic Breast Cancer | View | |
| NCT00519324 | Efficacy and Safety of Everolimus RAD001 in Patients With Advanced Gastric Cancer | View | |
| NCT01482156 | Dose Finding Study of RAD001 Everolimus Afinitor in Combination With BEZ235 in Patients With Advanced Solid Tumors | View | |
| NCT00522665 | Phase IRandomized Phase II Study of Second Line Therapy With Irinotecan Cetuximab - RAD001 for Colorectal Cancer | View | |
| NCT01495247 | Phase IbII Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative Locally Advanced or Metastatic Breast Cancer | View | |
| NCT01927588 | Evaluation of Early Use of Everolimus EVE on Cytomegalovirus CMV Infection in Renal Transplant Recipients | View | |
| NCT00560963 | Treatment of Patients Suffering From a Progressive Pancreas Carcinoma With Everolimus RAD001 and Gemcitabine | View | |
| NCT00574366 | Erlotinib and Everolimus in Treating Patients With Metastatic Breast Cancer | View | |
| NCT01520103 | Study to Compare Vinorelbine In Combination With the mTOR Inhibitor Everolimus vs Vinorelbin Monotherapy for Second-line Treatment in Advanced Breast Cancer | View | |
| NCT01522820 | Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors | View | |
| NCT01535989 | Study of Inotuzumab Ozogamicin Temsirolimus in Patients With Relapsed or Refractory CD22 B-cell NHLymphoma | View | |
| NCT00655655 | Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors | View | |
| NCT02438761 | PF-05212384 PKI-587 for t-AMLMDS or de Novo Relapsed or Refractory Acute Myeloid Leukemia AML | View | |
| NCT01952847 | Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis | View | |
| NCT01566279 | A Study to Identify a Biomarker Predictive for Response on Everolimus in Solid Tumors CPCT-03 | View | |
| NCT00727207 | Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy | View | |
| NCT04542733 | The Efficacy of Everolimus With Reduced-dose Tacrolimus Versus Reduced-dose Tacrolimus in Treatment of BK Virus Infection in Kidney Transplantation Recipient | View | |
| NCT00736970 | Oral Deforolimus With Trastuzumab for Patients With HER2-positive Trastuzumab-Refractory Metastatic Breast Cancer 8669-009 | View | |
| NCT00742105 | Phase I Study to Determine the Maximum Tolerate Dose MTD of BGT226 in Advanced Solid Tumors in Japan | View | |
| NCT01596140 | Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer | View | |
| NCT00789828 | Efficacy and Safety of Everolimus RAD001 in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex TSCEXIST-1 | View | |
| NCT00792766 | Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis TSC and Sporadic Lymphangioleiomyomatosis LAM | View | |
| NCT01750567 | A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia CLL and Untreated CLL | View | |
| NCT00811590 | Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers Syndrome | View | |
| NCT01620307 | Rapamune Improves Outcomes of Severe H1N1 Pneumonia | View | |
| NCT04582136 | Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus | View | |
| NCT00836927 | Extension Trial of Deforolimus Ridaforolimus MK-8669 in Participants With Advanced Cancer MK-8669-038 | View | |
| NCT01637090 | Everolimus in Treating Cutaneous T-cell Lymphoma | View | |
| NCT02306135 | Identifying Mechanisms of Resistance to mTOR Inhibitors in Cancer | View | |
| NCT02833506 | Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Fallopian Tube or Primary Peritoneal Cancer | View | |
| NCT00869999 | Everolimus Plus Rituximab for RelapsedRefractory Diffuse Large B Cell Lymphoma | View | |
| NCT00863655 | Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole | View | |
| NCT02201212 | Everolimus for Cancer With TSC1 or TSC2 Mutation | View | |
| NCT00877773 | Phosphatidylinositol 3 Kinase and Mammalian Target of Rapamycin PI3K-mTOR in Advanced Cancer Patients | View | |
| NCT01640743 | Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney Transplantation | View | |
| NCT01649609 | Using mTOR Inhibitors in the Prevention of BK Nephropathy | View | |
| NCT00918333 | Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma Non-Hodgkin Lymphoma or Hodgkin Lymphoma | View | |
| NCT00923273 | Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer | View | |
| NCT01658176 | Study Of PF-04691502 PI3KmTOR Inhibitor In Combination With Exemestane Compared With Exemestane Alone In Patients With Advanced Breast Cancer | View | |
| NCT02215720 | Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors | View | |
| NCT01665768 | Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma | View | |
| NCT02216786 | A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer | View | |
| NCT02312661 | Study of Metformin With CarboplatinPaclitaxel Chemotherapy in Patients With Advanced Ovarian Cancer | View | |
| NCT00975819 | Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies | View | |
| NCT00999882 | Safety Tolerability Pharmacokinetics PK and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients | View | |
| NCT01670175 | Sirolimus With Cyclophosphamide and Topotecan for PediatricAdolescent Relapsed and Refractory Solid Tumors | View | |
| NCT01014351 | Study of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma | View | |
| NCT01026792 | Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent Locally Advanced Metastatic or Cannot Be Removed By Surgery | View | |
| NCT01026402 | Study to Assess the Safety Tolerability Pharmacokinetics PK and Preliminary Efficacy of AZD2014 | View | |
| NCT01026623 | Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer | View | |
| NCT01028092 | mTor-inhibitor EVERolimus Based Immunosuppressive Strategies for CNI Minimisation in OLD for Old Renal Transplantation | View | |
| NCT02444390 | Molecular Alterations Associated With Resistance to Endocrine Therapy and Impacting Treatment With mTOR Inhibitor | View | |
| NCT01077986 | Everolimus Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer | View | |
| NCT01070316 | Everolimus RAD001 Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex TSC | View | |
| NCT01072890 | Temsirolimus and Pazopanib in Patients With Advanced Solid Tumors | View | |
| NCT01713946 | A Placebo-controlled Study of Efficacy Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex TSC Refractory Partial-onset Seizures | View | |
| NCT01154335 | Everolimus and OSI-906 for Patients With Refractory Metastatic Colorectal Cancer | View | |
| NCT01725490 | The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis Double Blinded Randomized Controlled Study | View | |
| NCT01162551 | Trial of Sirolimus and Methotrexate in RelapsedRefractory Lymphoblastic Leukemia and Lymphoma | View | |
| NCT01174199 | Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer | View | |
| NCT01184898 | Pilot Trial of SirolimusMEC in High Risk Acute Myelogenous Leukemia AML | View | |
| NCT01195376 | A Study of BEZ235 in Adult Japanese Patients With Advanced Solid Tumors | View | |
| NCT01194193 | Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours | View | |
| NCT01205672 | Evaluation of the Molecular Effects of Metformin on the Endometrium in Patients With Endometrial Cancer | View | |
| NCT01204476 | Cixutumumab Everolimus and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma | View | |
| NCT01217177 | A Study of mTOR Inhibitor Everolimus RAD001 in Association With Cisplatin and Radiotherapy for Locally Advanced Cervix Cancer | View | |
| NCT01730209 | Efficacy of RAD001Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex | View | |
| NCT01734512 | PNOC 001 Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children | View | |
| NCT01223027 | Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma | View | |
| NCT01248494 | PhIb BKM120 or BEZ235Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor Metastatic Breast Cancer | View | |
| NCT04774952 | Dose Escalation of RMC-5552 Monotherapy in RelapsedRefractory Solid Tumors | View | |
| NCT01266057 | Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer | View | |
| NCT01758575 | Clinical Evaluation of the Underlying Mechanisms of Targeted Therapy Related Toxicities | View | |
| NCT02432560 | Safety and Durability of Sirolimus for Treatment of LAM | View | |
| NCT01762033 | A Phase 2 Study of ASONEP to Treat Unresectable and Refractory Renal Cell Carcinoma | View | |
| NCT01332279 | Everolimus Erlotinib Hydrochloride and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy | View | |
| NCT01343498 | Study of PI3 KinasemTOR Inhibitor BEZ235 Twice Daily for Advanced Solid Tumors | View | |
| NCT01765946 | Metformin and Longevity Genes in Prediabetes | View | |
| NCT01358305 | Protein Blends Soy Whey and Casein for Muscle Synthesis | View | |
| NCT01374750 | Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma HCC | View | |
| NCT02451696 | A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD | View | |
| NCT01383668 | Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancer | View | |
| NCT01417065 | Temsirolimus In Phase 0 | View | |
| NCT01797120 | Study of Fulvestrant - Everolimus in Post-Menopausal Hormone-Receptor Metastatic Breast Ca Resistant to AI | View | |
| NCT04895748 | DFF332 as a Single Agent and in Combination With Everolimus Immuno-Oncology Agents in AdvancedRelapsed Renal Cancer Other Malignancies | View | |
| NCT00928018 | TacrolimusSirolimusMethotrexate vs TacrolimusMethotrexate or CyclosporineMycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma | View | |
| NCT01536054 | Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial Fallopian Tube or Primary Peritoneal Cavity Cancer | View | |
| NCT03099499 | Single Agent ONC201 in Recurrent or Metastatic Endometrial Cancer | View | |
| NCT01567488 | Phase II Study of Everolimus Combined With Octreotide LAR to Treat Advanced GI NET | View | |
| NCT01561404 | Effect of the Inhibition of the Mammalian Target of Rapamycin on Metabolism and Exercise | View | |
| NCT01582009 | Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate | View | |
| NCT03047213 | Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With TSC1 andor TSC2 Mutations | View | |
| NCT04980872 | A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib MK-7075 in Other Studies MK-7075-006 | View | |
| NCT01624766 | Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers | View | |
| NCT01633060 | A Phase III Study of BKM120 With Fulvestrant in Patients With HRHER2- AI Treated Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi | View | |
| NCT01658436 | BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors pNET After Failure of mTOR Inhibitor Therapy | View | |
| NCT01661283 | SARC016 Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors | View | |
| NCT02978547 | The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal Adenocarcinoma | View | |
| NCT01737502 | Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer | View | |
| NCT05093218 | Effect of Branch Chain Amino Acid Therapy on Sarcopenia in Children With Chronic Liver Disease | View | |
| NCT01756118 | A Phase I Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia | View | |
| NCT03091465 | Validation of the International Metastatic Renal Cell Carcinoma Database Consortium IMDC Prognostic Classification for Targeted Therapies TKImTOR Inhibitors in Second Line After First Line Treatment With Pazopanib | View | |
| NCT01807767 | Myfortic in High MELD Liver Transplantation | View | |
| NCT03319173 | Dietary Ketosis Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation | View | |
| NCT01854606 | Safety and Efficacy of AEB071 and EVEROLIMUS in Patients With CD79-mutant or ABC Subtype Diffuse Large B-Cell Lymphoma | View | |
| NCT05198427 | mTOR Inhibitors the Lesions Induced by Papillomavirus for Transplant Patients | View | |
| NCT01935128 | Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to EverolimusReduced Tacrolimus in Renal Transplant Recipients Following Campath Induction | View | |
| NCT01991938 | Phase I Dose Escalation Study of VS-5584 in Subjects With Advanced Non-Hematologic Malignancies or Lymphoma | View | |
| NCT02008877 | SARC023 Ganetespib and Sirolimus in Patients With MPNST Malignant Peripheral Nerve Sheath Tumors | View | |
| NCT05285878 | Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation | View | |
| NCT02049047 | Study of Everolimus in Patients With Thymoma and Thymic Carcinoma Previously Treated With Chemotherapy | View | |
| NCT01510119 | Autophagy Inhibition to Augment Mammilian Target of Rapamycin mTOR Inhibition A Phase III Trial of RAD001 and Hydroxychloroquine HCQ in Patients With Previously Treated Renal Cell Carcinoma | View | |
| NCT02134899 | The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients | View | |
| NCT02142803 | TORC12 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors | View | |
| NCT02166944 | Tamoxifen Treatment in Patients With Motor Neuron Disease | View | |
| NCT05414292 | Impacts of Mechanistic Target of Rapamycin mTOR Inhibition on Aged Human Muscle Rapamune | View | |
| NCT01811667 | Efficacy and Safety of the Mammalian Target of Rapamycin mTor Rapamycin Inhibitor in Vascular Malformations | View | |
| NCT02238496 | Perifosine and Torisel Temsirolimus for RecurrentProgressive Malignant Gliomas | View | |
| NCT05445791 | Metformin Plus Tyrosine Kinase Inhibitors for Treatment of Patients With Non-small Cell Lung Cancer With EGFR Mutations | View | |
| NCT00563147 | A Phase 1b Open-Label Dose-Finding Study to Evaluate the Safety of Tivozanib AV-951 in Combination With Temsirolimus in Subjects With Metastatic Renal Cell Carcinoma | View | |
| NCT02305810 | A Biological Prospective Study in Patients With Metastatic Pancreatic NETs Treated With Everolimus | View | |
| NCT02337309 | SF1126 for Patients With Relapsed or Refractory Neuroblastoma | View | |
| NCT02331966 | Molecular Pathways Involved in the Pathogenesis and Behavior of Mesenchymal Phosphaturic Tumors Causing Oncogenic Osteomalacia | View | |
| NCT02330783 | Efficacy and Safety of Bevacizumab Plus Sorafenib for the Third-line Treatment in Metastatic Renal Cancer Patients | View | |
| NCT01046045 | Everolimus Rescue Immunosuppression in the Treatment of Chronic Allograft Dysfunction in Renal Transplant Recipients | View | |
| NCT05557292 | RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma | View | |
| NCT05571670 | Bile Acids in Acute Insulin Resistance | View | |
| NCT02429869 | Impact of Everolimus on HIV Persistence Post Kidney or Liver Transplant | View | |
| NCT02441543 | Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus | View | |
| NCT02499458 | Prospective Validation of Circulating Tumor Cells Circulating Endothelial Cells as Biomarkers in Renal Cancer | View | |
| NCT03730142 | A Study of WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma | View | |
| NCT03580239 | Everolimus in Castrated Resistant Prostate CancerCRPCPatients With PI3K-AKT-mTOR Signaling Pathway Deficiency | View | |
| NCT04200911 | Cognition Age and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway | View | |
| NCT02572206 | PET Imaging Study of Amish and Mennonite Patients With CNTNAP2 Mutations | View | |
| NCT02646319 | Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations | View | |
| NCT00337376 | A Study of the mTOR Inhibitor Rapamycin Rapamune Sirolimus in Combination With Abraxane in Advanced Solid Cancers | View | |
| NCT02688881 | Study to Evaluate the Safety and Efficacy of Sirolimus in Subject With Refractory Solid Tumors | View | |
| NCT02687958 | Study of Everolimus as Maintenance Therapy for Metastatic NEC With Pulmonary or Gastroenteropancreatic Origin | View | |
| NCT02684032 | A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With PalbociclibLetrozole Or PalbociclibFulvestrant In Women With Metastatic Breast Cancer | View | |
| NCT05746689 | Study of Sirolimus in IgG4-related Disease | View | |
| NCT05773326 | Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG | View | |
| NCT03781050 | Efficacy of Rapamycin Sirolimus in the Treatment of Peutz-Jeghers Syndrome | View | |
| NCT02850744 | Study to Evaluate the Efficacy Safety Pharmacokinetics and Pharmacodynamic Effects of PQR309 in Glioblastoma Patients | View | |
| NCT02864615 | Safety and Preliminary Efficacy of SBRT in Patients With Metastatic RCC Treated With Targeted or IO Therapy | View | |
| NCT02988986 | TAK-228 Plus Tamoxifen in Patients With ER-Positive HER2-negative Breast Cancer | View | |
| NCT03016715 | Using Topical Sirolimus 2 for Patients With Epidermolysis Bullous Simplex EBS Study | View | |
| NCT04348292 | Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer | View | |
| NCT04482712 | Effects of mTOR Inhibition With Sirolimus RAPA in Patients With COVID-19 to Moderate the Progression of ARDS | View | |
| NCT06018766 | LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome | View | |
| NCT03129724 | Retrospective Study in Patients With Metastatic Renal Cancer Treated With TKI Sequence Tyrosine Kinase Inhibitors of VEGFR - mTOR- Axitinib Inhibitors or Anti-VEGF Antibody -Inhibiteurs mTOR - Axitinib | View | |
| NCT01847261 | Effects of Protein Blends on Muscle Protein Synthesis in Healthy Older Adults | View | |
| NCT03433183 | SARC031 MEK Inhibitor Selumetinib AZD6244 in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors | View | |
| NCT03525834 | Safety and Efficacy of Everolimus Afinitor in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex | View | |
| NCT06257420 | Rapamycin in Myalgic EncephalomyelitisChronic Fatigue Syndrome | View | |
| NCT04690725 | TQB3525 for Advanced Bone Sarcomas With PI3KA Mutations or PTEN Loss | View | |
| NCT05470218 | Leucine mTOR and Athero | View | |
| NCT03767660 | Efficacy of Rapamycin Sirolimus in the Treatment of BRBNS Hereditary or Sporadic Venous Malformation | View | |
| NCT04936971 | Introduction of mTor Inhibitors and the Activation of the Cytomegalovirus CMV -Specific Cellular Immune Response | View | |
| NCT03817515 | Expanded Access for ABI-009 in Patients With Advanced PEComa and Patients With a Malignancy With Relevant Genetic Mutations or mTOR Pathway Activation | View | |
| NCT05104983 | Stopping TSC Onset and Progression 2B Sirolimus TSC Epilepsy Prevention Study | View | |
| NCT06463028 | Sapanisertib and Serabelisib PIKTOR With Paclitaxel Serabelisib With Paclitaxel and Paclitaxel Alone in Patients With AdvancedRecurrent Endometrial Cancer | View | |
| NCT04094675 | Sirolimus for Cowden Syndrome With Colon Polyposis | View | |
| NCT04112537 | Dermatologic Patterns of Tuberous Sclerosis Patients and Somatic Mutation Relationship | View | |
| NCT04139915 | Effect of RTB101 on Illness Associated With Respiratory Tract Infections in the Elderly | View | |
| NCT01856101 | Study of BEZ235 as Monotherapy in Patients With Transitional Cell Carcinoma After Failure of Platinum Based Chemotherapy | View | |
| NCT01857193 | Phase Ib Trial of LEE011 With Everolimus RAD001 and Exemestane in the Treatment of Hormone Receptor Positive HER2 Negative Advanced Breast Cancer | View | |
| NCT01855971 | Using Epigallocatechin Gallate EGCG and Cognitive Training to Modulate Cognitive Performance in Patients With Fragile X Syndrome TESFX | View | |
| NCT00087685 | RAD001 in Recurrent Endometrial Cancer Patients | View | |
| NCT04388371 | Glutamine PET Imaging in LAM | View | |
| NCT04409327 | Phase 2 Study to Determine if RTB101 Reduces the Severity of COVID-19 in Older Adults Residing in Nursing Homes | View | |
| NCT05949658 | Rapalog Pharmacology RAP PAC Study | View | |
| NCT04584710 | A Phase 2 Study of RTB101 as COVID-19 Post-Exposure Prophylaxis in Older Adults | View | |
| NCT05840510 | Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation KRYSTAL -19 | View | |
| NCT04742777 | Effect of mTOR Inhibition Other Metabolism Modulating Interventions on the Elderly SubStudy Rapa cMRI to Evaluate Cardiac Function | View | |
| NCT04759729 | The Effect of Probiotics and Vitamin D Supplementation on Sport Performance in MMA Athletes | View | |
| NCT01090466 | Gemcitabine Hydrochloride Cisplatin and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced andor Metastatic Transitional Cell Cancer of the Urothelium | View | |
| NCT01529554 | Controlled Level EVERolimus in Acute Coronary Syndromes | View | |
| NCT05103358 | Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1TSC2 Genes PRECISION 1 | View | |
| NCT00971789 | Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes | View | |
| NCT05192850 | Endometrial Cancer Recurrence in Patients Taking Metformin | View | |
| NCT00622258 | A Phase I Dose Escalation Study of RAD001 Administered in Patients With Relapsed or Refractory Non-Hodgkins Lymphoma | View | |
| NCT05233722 | mTOR as Mediator of Insulin Sensitivity Study | View | |
| NCT06205381 | Assessment of the Safety Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers | View | |
| NCT06472388 | Everolimus 5 mg vs 10 mgDaily for Patients With Neuroendocrine Tumors | View | |
| NCT06646809 | Reducing Inflammatory Syndrome in Surgery - Colorectal RISIS-CR Trial | View | |
| NCT06545526 | Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis | View | |
| NCT06548867 | Retrospective Analysis of Patients With Metastatic Renal Cell Carcinoma Treated With CABOzantinib | View | |
| NCT06607198 | Clinical-pathological Evaluation of Pit-NETs | View | |
| NCT06504225 | EVEROLD LONG TERM FOLLOW-UP | View | |
| NCT01911247 | Preoperative Window Study of Metformin for the Treatment of Endometrial Cancer | View | |
| NCT05458492 | Sirolimus in Cutaneous Sarcoidosis | View | |
| NCT06612593 | Cilostazol in Parkinson39s Disease | View | |
| NCT06615934 | Effects of Aerobic and Resistance Exercises on Inpatients Liver Transplantation Recipients | View | |
| NCT05508906 | Phase 1b Combo w Ribociclib Alpelisib or Everolimus | View | |
| NCT02587325 | Phase 11b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial Hypertension | View | |
| NCT00634270 | A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas | View | |
| NCT00704054 | A Multi-Center Phase I Study of Intravenous Deforolimus AP23573 MK-8669 Administered QDX5 Every Other Week in Pediatric Patients With Advanced Solid Tumors 8669-028COMPLETED | View | |
| NCT00781846 | Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers 8669-010COMPLETED | View | |
| NCT06584773 | Efficacy of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients | View | |
| NCT02019979 | Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIBIV Non-Squamous Non-Small Cell Lung Cancer NS-NSCLC | View | |
| NCT02023905 | Everolimus With and Without Temozolomide in Adult Low Grade Glioma | View | |
| NCT00876395 | Everolimus in Combination With Trastuzumab and Paclitaxel in the Treatment of HER2 Positive Locally Advanced or Metastatic Breast Cancer | View | |
| NCT02626507 | Phase I Study of Combination of Gedatolisib With Palbociclib and Faslodex in Patients With ERHER2- Breast Cancer | View | |
| NCT00891696 | Nutritional and Contractile Regulation of Muscle Growth | View | |
| NCT05835999 | Everolimus Aging Study | View | |
| NCT05833815 | Addition of Everolimus to Standard of Care in Carcinoma Gallbladder | View | |
| NCT00936858 | RAD001 for Patients With Radioiodine Refractory Thyroid Cancer | View | |
| NCT03333694 | Safety Tolerability and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ SCCis | View | |
| NCT00962507 | Panobinostat and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma | View | |
| NCT00122343 | AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer 8669-019COMPLETED | View | |
| NCT00124280 | Study Investigating the Effect of Everolimus Monotherapy in Patients With Advanced Non-small Cell Lung Cancer NSCLC | View | |
| NCT05997056 | Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors NETs of the Gastrointestinal Tract Lung or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors | View | |
| NCT01050985 | A Study of Temsirolimus Plus Capecitabine in Patients With Advanced Cancer | View | |
| NCT01058655 | RAD001 and AV-951 in Patients With Refractory Metastatic Colorectal Cancer | View | |
| NCT01075321 | Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma | View | |
| NCT06053671 | Mos-FED Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue | View | |
| NCT01141309 | Evaluating the Combination of Everolimus and Sorafenib in the Treatment of Thyroid Cancer | View | |
| NCT01152827 | RAD001 in Pheochromocytoma or Nonfunctioning Carcinoid | View | |
| NCT01166126 | TemsirolimusAZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV | View | |
| NCT01178151 | Study of Everolimus in the Treatment of Advanced Malignancies in Patients With Peutz-Jeghers Syndrome | View | |
| NCT01177397 | Study to Assess Safety Pharmacokinetics and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors Non-Hodgkin Lymphoma or Multiple Myeloma | View | |
| NCT01198665 | RAD001 Combined With CHOP in Newly Diagnosed Peripheral T-cell Lymphomas | View | |
| NCT02055079 | Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease | View | |
| NCT01246817 | Temsirolimus-RCC-imaging | View | |
| NCT01240460 | Exploratory Study of XL765 SAR245409 or XL147 SAR245408 in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection | View | |
| NCT01272141 | A Study of Lapatinib in Combination With Everolimus in Patients With Advanced Triple Negative Breast Cancer | View | |
| NCT06301386 | Everolimus Combined With PD-1 in Advanced Colorectal Cancer Patients | View | |
| NCT00253318 | RAD001 Plus Docetaxel in Patients With Metastatic Breast Cancer | View | |
| NCT02064608 | Investigating the Effects of AZD2014 Therapy Given Prior to Radical Prostatectomy in Men With High Risk Prostate Cancer | View | |
| NCT01338090 | 89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors | View | |
| NCT01335074 | Temsirolimus Sorafenib in Advanced Hepatocellular Carcinoma HCC | View | |
| NCT01341834 | Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors | View | |
| NCT06341998 | Clinical Study of Chemotherapy in the Treatment of RecurrentRefractory Yolk Sac Tumor in Children | View | |
| NCT01390818 | Trial of MEK Inhibitor and PI3KmTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors | View | |
| NCT06385496 | Testing MLN0128 TAK-228 as Potentially Targeted Treatment in Cancers With mTOR Genetic Changes MATCH - Subprotocol L | View | |
| NCT06437574 | Intensive Cholesterol-Lowering and CD8 T Cells in Prostate Cancer | View | |
| NCT00770120 | S0722 Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery | View | |
| NCT02091531 | Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer CRPC Patients | View | |
| NCT02104011 | Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers | View | |
| NCT00777699 | Safety Study of XL765 SAR245409 in Combination With Erlotinib in Adults With Solid Tumors | View | |
| NCT02110069 | A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors | View | |
| NCT00704080 | A Study of XL765 SAR245409 in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas | View | |
| NCT00985192 | Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer | View | |
| NCT02145312 | An Open Label Single Arm Multicenter Phase II Study of BYL719 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck Who Failed to Respond to Platinum-based Therapy | View | |
| NCT02145559 | A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors | View | |
| NCT02644122 | SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene andor PI-3 Kinase Pathway Genes | View | |
| NCT03356769 | Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex | View | |
| NCT03972592 | Topical Sirolimus in Cutaneous Lymphatic Malformations | View | |
| NCT02155920 | Everolimus for Children With Recurrent or Progressive Ependymoma | View | |
| NCT03955172 | Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated Rejection | View | |
| NCT00411619 | Everolimus RAD001 Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex | View | |
| NCT01548807 | Phase 1 Trial of the Mammalian Target of Rapamycin mTOR Inhibitor Everolimus Plus Radiation Therapy RT for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy | View | |
| NCT00973076 | Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055 | View | |
| NCT00901849 | TarcevaRapamycin for Children With Low-grade Gliomas With or Without Neurofibromatosis Type 1 NF1 | View | |
| NCT00890253 | Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation | View | |
| NCT01517243 | Phase II Study of Alternating Sunitinib and Temsirolimus | View | |
| NCT01014234 | Rapamycin and Regulatory T Cells in Kidney Transplantation | View | |
| NCT01195922 | Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma | View | |
| NCT01275222 | Everolimus in Combination With Imatinib in Patients With Glivec RefractoryResistant Gastrointestinal Stromal Tumors | View | |
| NCT01226056 | Sorafenib in Combination With RAD001 in Advanced Solid Tumors Selected on Molecular Targets | View | |
| NCT02244463 | A Phase III Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer and Incurably Poorly Differentiated or Radioidodine Refractory Differentiated Thyroid Cancer | View | |
| NCT02246127 | Efficacy and Safety of Everolimus and STZ-5FU Given One Upfront the Other Upon Progression in Advanced Pancreatic Neuroendocrine Tumor pNET | View | |
| NCT01353625 | Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors and Hematologic Malignancies | View | |
| NCT01412515 | A Phase II Study With Tumor Molecular Pharmacodynamic MPD Evaluation of Oral mTOR-inhibitor Everolimus RAD001 10 mg Daily in Patients Suffering From Classic or Endemic Kaposis Sarcoma | View | |
| NCT01430585 | Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer | View | |
| NCT01545947 | Study Assessing Safety Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer | View | |
| NCT01462006 | Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis IPF | View | |
| NCT01523977 | Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL | View | |
| NCT01526356 | Topical Rapamycin to Erase Angiofibromas in TSC | View | |
| NCT02730923 | Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1mTORC2 Inhibitor and Anastrozole VICTORIA | View | |
| NCT02755844 | Safety and Efficacy of Metronomic Cyclophosphamide Metformin and Olaparib in Endometrial Cancer Patients | View | |
| NCT04128722 | TOPical Sirolimus in linGUal Microcystic Lymphatic Malformation -TOPGUN | View | |
| NCT05549167 | Efficacy and Safety of Sirolimus in Children and Adolescents With Juvenile Nasopharyngeal Angiofibroma JNA | View | |
| NCT02279758 | A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors | View | |
| NCT03174171 | Open-label Study on Treatment of Primary Aldosteronism With Everolimus | View | |
| NCT00317720 | Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 HER-2 Overexpressing Breast Cancer | View | |
| NCT02328963 | Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A | View | |
| NCT00060645 | Safety Study of AP23573 in Patients With Advanced Refractory or Recurrent Malignancies 8669-013COMPLETED | View | |
| NCT00474929 | Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma | View | |
| NCT00574769 | Safety Study Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate Cancer | View | |
| NCT00632268 | Low-dose RAD001Everolimus Plus Cisplatin-HDFL Chemotherapy for the First-line Treatment of Advanced Gastric Cancer | View | |
| NCT00703807 | Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial Cancers | View | |
| NCT00747851 | NETs Protection or Harm in Neonatal Inflammation or Infection | View | |
| NCT00748696 | Combined Effects of Resistance Training and Nutritional Supplements in the Treatment of Sarcopenia | View | |
| NCT00769483 | MK-0646 and Gemcitabine - Erlotinib for Patients With Advanced Pancreatic Cancer | View | |
| NCT00760383 | Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation | View | |
| NCT00790400 | Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex TSC or Sporadic Lymphangioleiomyomatosis LAM | View | |
| NCT00819546 | RAD001 in Combination With PKC412 in Patients With Relapsed Refractory or Poor Prognosis AML or MDS | View | |
| NCT02504892 | Everolimus Therapy in People With Birt-Hogg-Dube Syndrome BHD-Associated Kidney Cancer or Sporadic Chromophobe Renal Cancer | View | |
| NCT02596828 | Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma | View | |
| NCT02638389 | Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard Care | View | |
| NCT02711826 | Treg Therapy in Subclinical Inflammation in Kidney Transplantation | View | |
| NCT02821507 | Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and Chondrosarcoma | View | |
| NCT02874924 | Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly | View | |
| NCT02881697 | mTOR and Adipose Tissue Inflammation | View | |
| NCT02890641 | Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies | View | |
| NCT02901132 | Association Between Different Parameters of Nutritional Assessment and Clinical Outcomes in Cancer Patients | View | |
| NCT02960997 | Using Topical Sirolimus 2 for Patients With Epidermolysis Bullous Simplex EBS Study | View | |
| NCT02987959 | Study of TAK-228 MLN0128 in Soft Tissue Sarcomas | View | |
| NCT02990312 | Impact of Sirolimus and Maraviroc on CCR5 Expression and the HIV-1 Reservoir in HIV-infected Kidney Transplant Recipients | View | |
| NCT03017521 | K-BASKET TAS-117 PI3KAKT Gene Aberration | View | |
| NCT03114826 | Study of the Impact of VEGF Polymorphism on the Development of Renal Carcinoma in Renal Transplant Patients | View | |
| NCT03176238 | Study in Post-menopausal Women With Hormone Receptor Positive HER2-negative Advanced Breast Cancer | View | |
| NCT03190174 | Nivolumab Opdivo Plus ABI-009 Nab-rapamycin for Advanced Sarcoma and Certain Cancers | View | |
| NCT03309007 | A Double-Blind Placebo-Controlled Trial of Anti-Aging Pro-Autophagy Effects of Metformin in Adults With Prediabetes | View | |
| NCT03308747 | Inflammaging and Muscle Protein Metabolism | View | |
| NCT03328104 | Everolimus in Combination With Nelarabine Cyclophosphamide and Etoposide in Lymphoblastic LeukemiaLymphoma | View | |
| NCT03486366 | Application of Novel Diagnostic and Therapeutical Methods in Epilepsy and Neurodevelopmental Abnormalities in Children | View | |
| NCT03946774 | Dietary Protein and MonocyteMacrophage Mammalian Target of Rapamycin mTOR Signaling | View | |
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