Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
AXL
Name:
AXL receptor tyrosine kinase
Location:
19q13.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT01561456 | Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung | View | |
| NCT03572634 | Phase 12 Study of TP-0903 an Inhibitor of AXL Kinase in Patients With Previously Treated CLL | View | |
| NCT02729298 | First-in-human Study of Oral TP-0903 a Novel Inhibitor of AXL Kinase in Patients With Advanced Solid Tumors | View | |
| NCT03425201 | Niraparib in Combination With Cabozantinib XL184 in Patients With Advanced Urothelial Cancer NICARAGUA | View | |
| NCT03536208 | Biological Effect of Warfarin on Pancreatic Cancer | View | |
| NCT03965494 | AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery | View | |
| NCT04322630 | Mer-TK in Human Cardiac Cells | View | |
| NCT05346536 | Liquid Biopsy and Pancreas Cancer Detection of AXL CTCs CTC-AXL-PANC | View | |
| NCT05551715 | Virtual Eye Model System for Personalised Refractive Surgery Treatment | View | |
| NCT04316182 | Cabozantinib in Patients With Hepatocellular Carcinoma ACTION | View | |
| NCT01639508 | Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes ROS1 or NTRK Fusions or Increased MET or AXL Activity | View | |
| NCT04458259 | Study of PF-07265807 in Participants With Metastatic Solid Tumors | View | |
| NCT00697632 | Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies | View | |
| NCT00785278 | Adjusting Wheelchair Set-Up to Minimize Shoulder Joint Forces During Propulsion | View | |
| NCT02219711 | Phase 11b Study of MGCD516 in Patients With Advanced Cancer | View | |
| NCT01062620 | A Dose Escalating Clinical Trial of the IGF-1 Receptor Inhibitor AXL1717 in Patients With Advanced Cancer | View | |
| NCT01139333 | Blood and Tumor Tissue Samples From Young Patients With Acute Myeloid Leukemia | View | |
| NCT03454243 | Oral Immunomodulatory Tyrosine Kinase Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors | View | |
| NCT03393936 | Safety and Efficacy of CCT301 CAR-T in Adult Subjects With Recurrent or Refractory Stage IV Renal Cell Carcinoma | View | |
| NCT05389462 | A Study of Mipasetamab Uzoptirine ADCT-601 in Participants With Solid Tumors | View | |
| NCT03522142 | A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies | View | |
| NCT02424617 | A Study of BGB324Bemcentinib in Combination With Erlotinib in Patients With Non-Small Cell Lung Cancer | View | |
| NCT02488408 | A Phase IbII Multicenter Open-label Study of Bemcentinib BGB324 in Patients With AML or MDS | View | |
| NCT05740917 | To Evaluate the Phase I Clinical Study of XZB-0004 in Patients With AML and MDS | View | |
| NCT03990454 | Safety Study of SLC-391 in Subjects With Solid Tumors | View | |
| NCT02988817 | Enapotamab Vedotin HuMax-AXL-ADC Safety Study in Patients With Solid Tumors | View | |
| NCT03176277 | A Study of ONO-7475 in Patients With Acute Leukemias | View | |
| NCT04600219 | The Effect of Tyrosine Kinase Receptor Axl on Dialysis Prognosis in Chronic Hemodialysis Patients | View | |
| NCT03396003 | A Comparison of Two Devices for Taking Measurements of the Eye to Assist in Lens Selection for Cataract Surgery | View | |
| NCT03425279 | CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma | View | |
| NCT04681131 | CAB-AXL-ADC Safety and Efficacy Study in Adults with NSCLC | View | |
| NCT03649321 | Clinical Trial of Chemotherapy and Bemcentinib for Metastatic Pancreatic Cancer | View | |
| NCT06359847 | Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer | View | |
| NCT03769311 | Cetuximab in Head and Neck Cancer Patients | View | |
| NCT03824080 | Evaluating the Efficacy and Safety of Bemcentinib in Patients With Myelodysplastic Syndromes | View | |
| NCT04004442 | Avelumab in Combination With AVB-S6-500 in Patients With Advanced Urothelial Carcinoma | View | |
| NCT04045626 | Study of Demarcation Line Depth in Transepithelial Versus Epithelium-off Accelerated Cross-linking AXL in Keratocouns | View | |
| NCT04042623 | Study of Safety and Efficacy of AVB-S6-500 in Patients With IgA Nephropathy | View | |
| NCT05410717 | CLDN6GPC3MesothelinAXL-CAR-NK Cell Therapy for Advanced Solid Tumors | View | |
| NCT05860296 | Testing Experimental Anti-cancer Drug SLC-391 With an Approved Immunotherapy Drug Pembrolizumab for Advanced Lung Cancers | View | |
| NCT04895215 | AB-2004 in Treatment of Irritability Associated With Autism Spectrum Disorder ASD | View | |
| NCT05128786 | CCT301-38 CAR-T in Patients With Relapsed or Refractory AXL Positive Sarcomas | View | |
| NCT02034981 | Phase 2 Study Assessing Efficacy and Safety of Crizotinib in Patients Harboring an Alteration on ALK MET or ROS1 | View | |
| NCT05772455 | A Study of XZB-0004 in Patients With Solid Tumors | View | |
| NCT05816785 | Pilot Study of Imatinib Cetuximab Combo for H N Cancer | View | |
| NCT00949143 | Effects of Axle Positions on Wheelchair Skills in Manual Wheelchair Users | View | |
| NCT01014468 | Bevacizumab Versus Ranibizumab in Age Related Macular Degeneration | View | |
| NCT06049667 | A Phase 1 Clinical Trail of NTQ2494 Tablets in Patients With Advanced Hematological Malignancies | View | |
| NCT06231550 | A Study of Axl Inhibitor FC084CSA in Patients With Advanced Malignant Solid Tumors | View | |
| NCT06359860 | A Study of ST-1898 for Unresectable or Metastatic Melanoma | View | |
| NCT06499350 | A Study of FC084CSA in Combination of Tislelizumab in Patients With Advanced Malignant Solid Tumors | View | |
| NCT04129463 | Subscleral Trabeculectomy With Iris Incarceration in Buphthalmous | View | |
| NCT03198052 | GPC3MesothelinClaudin182GUCY2CB7-H3PSCAPSMAMUC1TGFβHER2Lewis-YAXLEGFR-CAR-T Cells Against Cancers | View | |
| NCT03607955 | Paclitaxel Carboplatin With AVB-S6-500 in Women With Stage III or IV Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancer Receiving Neoadjuvant Chemotherapy | View |