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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: MPL
Name: MPL proto-oncogene thrombopoietin receptor
Location: 01p34.2
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all

Clinical Studies

NCT Number Status Brief Title View
NCT00698568 Safety Evaluation of Herpes Simplex Candidate Vaccine gD2t With Adjuvant in HSV Seropositive Seronegative Subjects View
NCT00699231 Evaluation of Immunogenicity Reactogenicity and Safety of HBV-MPL Vaccine vs Engerix-B in Haemodialysis Patients View
NCT00806962 Phase 1 Norwalk Vaccine Study View
NCT02887690 Pilot Project to Evaluate the Revolutionizing Prosthetics Modular Prosthetic Limb System for Upper Extremity Amputees View
NCT02587767 577nm Micropulse Laser vs Half-dose Photodynamic Therapy on Acute Central Serous Chorioretinopathy View
NCT02851030 Move Play Learn Creating Active Classrooms in Early Care and Education Centers View
NCT00118625 Assessment of the Contribution of Monophosphoryl Lipid A MPL to a Tree Pollen Allergy Vaccine View
NCT05198960 AVAJAK ApixabanRivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms View
NCT05850273 Mechanism of Action of Interferon in the Treatment of Myeloproliferative Neoplasms View
NCT06159816 PREVALENCE STUDY OF PNH CLONES IN PATIENTS WITH NEOPLASIES View
NCT06246006 Functional Characterization of ThrombopoietincMPL Receptor Mutations in Myeloproliferative Neoplasia View
NCT04359771 Transfoveal Micropulse Laser for Center Involving Diabetic Macular Edema View
NCT00258635 Investigation of SafetyEfficacy of Different Doses of RagweedMATAMPLAssessment of Residual Allergenicity Using Skin Prick Test View
NCT00697931 Immunogenicity and Reactogenicity of MPL Adjuvanted Recombinant Hepatitis B- Vaccine and Engerix-B in Adult Non-Responders View
NCT00486382 Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adults in India View
NCT00107705 Assessment of Residual Allergenicity of Tree Birch Hazel and Alder Pollen Allergoid Using Skin Prick Testing View
NCT00116285 Assessment of Residual Allergenicity of Ragweed Pollen Allergoid With Monophosphoryl Lipid A MPL Using Skin Prick Testing View
NCT00118612 Different Doses of Tyrosine Adsorbed Tree Pollen Allergoid With Monophosphoryl Lipid A MPL in Patients Sensitized to Tree Pollen View
NCT00121849 Safety Study to Evaluate the Leish-111f MPL-SE Vaccine in the Prevention of Cutaneous Leishmaniasis in Healthy Subjects Previously Exposed to the Leishmania Parasite View
NCT00414141 Efficacy and SafetyTolerability of Grass MATA MPL View
NCT00423787 Efficacy and SafetyTolerability of Ragweed MATA MPL View
NCT00698906 Comparing Immunogenicity and Safety of Different Formulations of HBV-MPL Vaccine With Engerix-B in Adults Aged 19-40 y View
NCT00698087 Comparison of Safety Immuno- and Reactogenicity of MPL-Adjuvanted Recombinant Hepatitis B Vaccine to That of Engerix-B View
NCT00697775 Safety and Immunogenicity of GSK Bios Candidate HBV-MPL Vaccines Compared to Engerix-B in Healthy Adolescents View
NCT00698893 Evaluation of Safety of Candidate gD Vaccine With or Without MPL in Healthy Herpes Simplex Virus-positive Adults View
NCT00698555 Comparing Immunogenicity and Safety of Different Formulations of HBV-MPL Vaccine With Engerix-B in Adults Aged 18-40 y View
NCT00696917 Safety and Immunogenicity of 3 Lots of GSK Biologicals HBV-MPL Vaccine and Engerix-B in Healthy Volunteers 15y View
NCT00699764 Safety of a Herpes Simplex Candidate Vaccine gD2t With MPL and Its Efficacy to Prevent Genital Herpes Disease View
NCT00697853 Immunogenicity and Safety of GSK Biologicals HBV-MPL Vaccine 2 Doses and of Engerix-B 3 Doses in Healthy Adults View
NCT00696891 Study Comparing Immunogenicity Reactogenicity and Safety of GSK Bios HBV-MPL Vaccine With That of Engerix-B in Adults View
NCT00697242 Comparison of Immuno Reacto and Safety of Recombinant Hepatitis B Vaccine With or Without MPL in Healthy Older Adults View
NCT01011309 A Study of the Efficacy and Safety of the LEISH-F2 MPL-SE Vaccine for Treatment of Cutaneous Leishmaniasis View
NCT01751048 LEISH-F3 GLA-SE and the LEISH-F3 MPL-SE Vaccine View
NCT01168401 Bivalent Norovirus Vaccine Study View
NCT03116542 18F-FLT PETCT in PrefibroticEarly Primary Myelofibrosis and Essential Thrombocythemia View
NCT03121599 18F-FLT PETCT in Pediatrics With Myeloproliferative Neoplasms View
NCT02038907 Safety and Immunogenicity of Norovirus GI1GII4 Bivalent VLP Vaccine View
NCT00241410 Safety Immunological Effect and Efficacy of the Combined Application of MPL and Grass Pollen Allergen View
NCT02735213 Micropulse 577nm Laser vs Traditional Laser Treatment in Central Serous Chorioretinopathy View
NCT04285086 Ropeginterferon Alfa-2b P1101 vs Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance View
NCT03866746 Aflibercept With and Without Micropulse Laser in Diabetic Macular Edema View
NCT06493981 Outcomes in Bone Marrow Aplasia View
NCT00121862 Study to Evaluate the Leish-111f MPL-SE Vaccine in Healthy Adults Not Previously Exposed to Leishmania Parasite View
NCT04234438 Management of Cystoid Macular Edema Secondary to Retinitis Pigmentosa Via Subliminal Micropulse Yellow Laser View
NCT02582073 Dose Selection Study of Efficacy and Safety of Different Doses of Grass MATA MPL and Grass MATA Using mEECs View
NCT00697216 Immunogenicity and Safety of GSK Biologicals HBV-MPL Vaccine and Engerix-B in Healthy Adults 15-40 Yrs View
NCT00698061 Immunogenicity and Safety of an Adjuvanted HBV Vaccine Compared to Engerix-B in a Non-responder Population 15y View
NCT00697229 Immunogenicity Reactogenicity of HBV-MPL Vaccine and Engerix-B in Healthy Adults Following 2 Different Schedules View
NCT00982774 Safety and Immunogenicity of the LEISH-F2 MPL-SE Vaccine With SSG for Patients With PKDL View
NCT00138320 Herpevac Neonatal Substudy View
NCT00133146 Assessment of the Contribution of Monophosphoryl Lipid A MPL to a Grass Pollen Allergy Vaccine View
NCT00109759 Evaluation of Safety and Tolerability of Tyrosine Adsorbed Ragweed Pollen Allergoid With MPL Monophosphoryl Lipid A View
NCT06177431 An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease View
NCT00104390 Assessment of Residual Allergenicity of GrassRye Pollen Allergoid Using Skin Prick Testing View
NCT00111553 Study to Evaluate the Leish-111F MPL-SE Vaccine in the Treatment of Cutaneous Leishmaniasis View
NCT02174978 Phase 1 Clinical Trial With Controlled Human Malaria Infection CHMI to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults View
NCT00111514 Study to Evaluate the Leish-111F MPL-SE Vaccine in the Treatment of Mucosal Leishmaniasis View
NCT02784665 Treatment Trial for Acute Central Serous Chorioretinopathy View
NCT00133159 Different Doses of Tyrosine Adsorbed Grass Pollen Allergoid With Monophosphoryl Lipid A MPL in Patients Sensitized to Grass Pollen View
NCT00325338 Follow-up Investigation of Efficacy of Ragweed MATAMPLand Placebo in Patients With Ragweed-induced Seasonal Allergic Rhinitis View
NCT00731588 Red Blood Cell RBC Survival Following Transfusion in Infants View
NCT00888901 Platelet Function in Idiopathic Thrombocytopenic Purpura ITP Patients With Eltrombopag View
NCT02557633 A Study of Tolerability and Safety of Two New Doses of Grass MATA MPL View
NCT02681913 Adenosine as an Adjunct to Blood Cardioplegia View
NCT03311815 Diagnostic Platform to Perform Centralized and Standardized Rapid Molecular Diagnosis by Next Generation Sequencing NGS in Patients Diagnosed With Acute Myeloid Leukemia View
NCT03931993 A Study of Tolerability and Safety of a New Cumulative Dose of Grass MATA MPL View