Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
AQP4
Name:
aquaporin 4
Location:
18q11.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT04201470 | Serum Neurofilaments and GFAP in Atypical Multiple Sclerosis | View | |
| NCT02850705 | The French Cohort and Biobank of Devics Neuromyelitis Optica and Related Neurological Disorders NMOSD NOMADMUS | View | |
| NCT02865018 | Neuromyelitis Optica NMO Cetirizine | View | |
| NCT04463550 | GFAP Auto-immunity a French Cohort Study | View | |
| NCT05573711 | Restless Legs Syndrome in People With Neuromyelitis Optica Spectrum Disorder | View | |
| NCT05145361 | Clinical Study of B001 Injection in Subjects With Neuromyelitis Optic Spectrum Disorder NMOSD | View | |
| NCT05414890 | Sensitivity and Specificity of TSA-CBA for Autoantibodies Against Neural Antigen Determination | View | |
| NCT05549258 | Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder | View | |
| NCT02276963 | Ublituximab for Acute Neuromyelitis Optica NMO Relapses | View | |
| NCT03605238 | Treatment of Relapsed andor Refractory AQP4-IgG Seropositive NMOSD by Tandem CAR T Cells Targeting CD19 and CD20 | View | |
| NCT04553185 | Aquaporin-4 Single Nucleotide Polymorphisms in Patients With Idiopathic and Familial Parkinsons Disease | View | |
| NCT01112657 | An Observational Study on the Progression of Clinically Isolated Syndrome to Multiple Sclerosis Over a 2-year Period | View | |
| NCT01777412 | Efficacy of Bevacizumab Avastin in Treatment of Acute NMO Exacerbations | View | |
| NCT03350633 | Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders | View | |
| NCT05446701 | Assessment of Serum FAM19A5 Level in Egyptian Patients With Neuromyelitis Optica Spectrum Disorder | View | |
| NCT05605951 | Acute Optic Neuritis Network an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic Nerve | View | |
| NCT03819413 | Clinical Patterns of Neuromyelitis Optica Spectrum Disorders in Assiut University Hospital | View | |
| NCT03087136 | A Multicenter Observational Study to Evaluate Pediatric Multiple Sclerosis in Brazil | View | |
| NCT03766347 | Pediatric NMOSD Observational Study | View | |
| NCT05200728 | The Tolerability Safety and PK Characteristics of SIM1910-09 in Healthy Chinese Volunteers | View | |
| NCT04388072 | An Diagnostic Cohort on AQP4-Immunoglobulin G Detection Kit | View | |
| NCT05974293 | A Phase IIb Study of Nabiximols for Spasticity Due to Neuromyelitis Optica Spectrum Disorders | View | |
| NCT03514030 | Clinic Registry Study of Optic Neuromyelitis Spectrum Disease in China | View | |
| NCT05199688 | A Study To Evaluate Pharmacokinetics Efficacy Safety Tolerability And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder NMOSD | View | |
| NCT05269667 | A Study In Neuromyelitis Optica Spectrum Disorder NMOSD With Satralizumab As An Intervention | View | |
| NCT01892345 | A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO PREVENT Study | View | |
| NCT05284175 | A Study of Orelabrutinib in Patients With AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder | View | |
| NCT05346354 | Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD | View | |
| NCT06497374 | FcRn Antagonists Efgartigimod for Acute NMOSD Attack | View | |
| NCT02573792 | Optical Coherence Tomography and Optic Neuritis OCTON | View | |
| NCT05403138 | Safety and Efficacy of Daratumumab in Patients With Anti-Aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorders | View | |
| NCT05504694 | Ofatumumab in AQP4-IgG Seropositive NMOSD | View | |
| NCT06633042 | The Safety and Efficacy of Universal CAR-T Cells Targeting BCMA in the Treatment of Refractory NMOSD | View | |
| NCT05966467 | Registry of Patients With AQP4 NMOSD Treated With Alexion C5 Inhibitor Therapies | View | |
| NCT06044350 | A Clinical Trial of BAT4406F Injection in Patients With Neuromyelitis Optica Spectrum Disorders | View | |
| NCT06363162 | Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery | View | |
| NCT02893111 | Efficacy and Safety of Bortezomib as add-on Treatment in Relapsing Neuromyelitis Optica Spectrum Disorder | View | |
| NCT03062579 | A Longitudinal Study of ACTEMRA Tocilizumab as Monotherapy in Highly Active NMOSD | View | |
| NCT03586557 | Effectiveness of Plasma Exchange in Treating With Severe Acute AQP4-Ab Positive Optic Neuritis | View | |
| NCT04064944 | Comparison of the Efficacy and Safety of Immunoadsorption and Plasma Exchange for Acute Attack of Refractory Neuromyelitis Optica Spectrum Disorders | View |