Viewing Gene With Clinical Trials Data

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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: GRN
Name: granulin precursor
Location: 17q21.31
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all

Clinical Studies

NCT Number Status Brief Title View
NCT03636204 A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin GRN Mutation View
NCT04408625 Phase 12 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations FTD-GRN View
NCT04613089 Natural History and Longitudinal Clinical Assessments in NCL Batten Disease the International DEM-CHILD Database View
NCT04711161 First-in-Human Evaluation of GRN-300 in Subjects With Recurrent Ovarian Primary Peritoneal and Fallopian Tube Cancers View
NCT04747431 A Study of PBFT02 in Patients With Frontotemporal Dementia and Progranulin Mutations FTD-GRN View
NCT02696356 Phase 1 Study of GRN-1201 in HLA-A02 Subjects With Resected Melanoma View
NCT01835665 Dose Finding Study of Nimodipine for the Treatment of Progranulin Insufficiency From GRN Gene Mutations View
NCT05262023 A Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia FTD-GRN View
NCT04060082 Voices Of Individuals Challenges and Experiences Of bvFTD View
NCT02999282 Rehabilitative Trial for the Rescue of Neurophysiological Parameters in Progranulin Deficient Subjects View
NCT03116633 Concordance of Inivata Liquid Biopsy With Standard Tissue Biopsy View
NCT06064890 A Study to Evaluate the Safety and Effect of AVB-101 a Gene Therapy Product in Subjects With a Genetic Sub-type of Frontotemporal Dementia FTD-GRN View
NCT06226064 A Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of VES001 in Healthy Participants View
NCT04516499 Neurofilament Surveillance Project NSP View
NCT04639622 GENetic Fronto Temporal Dementia Initiative in Lille View
NCT05779813 Genetic Frontotemporal Dementia Initiative for Neurodevelopment View
NCT03417882 GRN-1201 With Pembrolizumab in Subjects With Metastatic PD-L1 NSCLC View