Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
GPC3
Name:
glypican 3
Location:
Xq26.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
Clinical Trials Data: https://classic.clinicaltrials.gov/api/gui/ref/download_all
Clinical Studies
| NCT Number | Status | Brief Title | View |
|---|---|---|---|
| NCT02876978 | Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma | View | |
| NCT02932956 | Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Patients With Pediatric Solid Tumors GAP | View | |
| NCT04506983 | GPC3-CAR-T Cells for the Hepatocellular Carcinoma | View | |
| NCT04093648 | T Cells co- Expressing a Second Generation Glypican 3-specific Chimeric Antigen Receptor With Cytokines Interleukin-21 and 15 as Immunotherapy for Patients With Liver Cancer TEGAR | View | |
| NCT04715191 | Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors | View | |
| NCT04377932 | Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors | View | |
| NCT05352542 | GPC3-targeting CART Cell in Treatment of Advanced Hepatocellular Carcinoma | View | |
| NCT05003895 | GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma HCC | View | |
| NCT05103631 | Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors | View | |
| NCT06198296 | Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells | View | |
| NCT02723942 | CAR-T Cell Immunotherapy for HCC Targeting GPC3 | View | |
| NCT03980288 | 4th Generation Chimeric Antigen Receptor T Cells Targeting Glypican-3 | View | |
| NCT04121273 | GPC3-targeted CAR-T Cell for Treating GPC3 Positive Advanced HCC | View | |
| NCT04842812 | Engineered TILsCAR-TILs to Treat Advanced Solid Tumors | View | |
| NCT03130712 | A Study of GPC3-targeted T Cells by Intratumor Injection for Advanced HCC GPC3-CART | View | |
| NCT02395250 | Anti-GPC3 CAR T for Treating Patients With Advanced HCC | View | |
| NCT02715362 | A Study of GPC3 Redirected Autologous T Cells for Advanced HCC | View | |
| NCT03084380 | Anti-GPC3 CAR-T for Treating GPC3-positive Advanced Hepatocellular Carcinoma HCC | View | |
| NCT03146234 | CAR-GPC3 T Cells in Patients With Refractory Hepatocellular Carcinoma | View | |
| NCT03198546 | GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression | View | |
| NCT04405778 | A Study of TAK-102 in Adult With Previously-Treated Solid Tumors | View | |
| NCT04864054 | T-Cell Therapy ECT204 in Adults With Advanced HCC | View | |
| NCT06427941 | A Phase 1 Study of BGB-B2033 Alone or in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors | View | |
| NCT03884751 | Chimeric Antigen Receptor T Cells Targeting Glypican-3 | View | |
| NCT06478693 | A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers Including HCC | View | |
| NCT05120271 | BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors | View | |
| NCT04076137 | Targeted T-cell Therapy in Solid Tumors | View | |
| NCT05410717 | CLDN6GPC3MesothelinAXL-CAR-NK Cell Therapy for Advanced Solid Tumors | View | |
| NCT05344664 | Novel GPC3 CAR-T Cell Therapy for Hepatocellular Carcinoma | View | |
| NCT04756648 | Phase I Clinical Trial of CT0180 Cells in the Treatment of Hepatocellular Carcinoma | View | |
| NCT04928677 | A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment | View | |
| NCT05047510 | GPC3 Targeted Fluorescence Image Guided Surgery of Hepatocellular Carcinoma | View | |
| NCT05070156 | B010-A Injection for Treating Patients With GPC3 Positive Advanced Hepatocellular Carcinoma | View | |
| NCT06383520 | Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma | View | |
| NCT06653023 | Universal CAR-T Cells REVO-UWD-03 for Advanced Hepatocellular Carcinoma and Lung Cancer | View | |
| NCT06461624 | Clinical Trial of Autologous GPC3 CAR-T Cells CBG166 Therapy for Advanced Hepatocellular Carcinoma | View | |
| NCT05620706 | Study of GPC-3 CAR-T Cells in Treating With Hepatocellular Carcinoma | View | |
| NCT05652920 | Ori-C101Chimeric Antigen Receptor CAR Modified T Cells for the Treatment of HCC | View | |
| NCT06590246 | A Study to Evaluate C-CAR031 in Glypican-3 GPC3 Advancedrecurrent Hepatocellular Carcinoma HCC | View | |
| NCT05783570 | To Evaluate the Safety Tolerability and Preliminary Efficacy of EU307 | View | |
| NCT05926726 | GPC3-directed CAR-T in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma | View | |
| NCT06641453 | CAR-T Cell Therapy Targeting GPC3 in Patients with Advanced GPC3-Positive Hepatocellular Carcinoma | View | |
| NCT06652243 | Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma | View | |
| NCT06084884 | A Phase III Study to Evaluate AZD5851 in GPC3 AdvancedRecurrent Hepatocellular Carcinoma | View | |
| NCT06088459 | NWRD06 DNA Plasmid for HCC After Radical Resection | View | |
| NCT06144385 | A Phase 1 Single-arm Open-label Dose-escalation Study of JWATM204 as T Cell-targeted Immunotherapy in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma | View | |
| NCT06196294 | GPC3Mesothelin-CAR-γδT Cells Against Cancers | View | |
| NCT02905188 | Glypican 3-specific Chimeric Antigen Receptor Expressing T Cells for Hepatocellular Carcinoma GLYCAR | View | |
| NCT03198052 | GPC3MesothelinClaudin182GUCY2CB7-H3PSCAPSMAMUC1TGFβHER2Lewis-YAXLEGFR-CAR-T Cells Against Cancers | View | |
| NCT03302403 | Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors | View |