Ignite Creation Date:
2025-12-25 @ 1:22 AM
Ignite Modification Date:
2025-12-25 @ 11:32 PM
Study NCT ID:
NCT01053793
Status:
COMPLETED
Last Update Posted:
2011-01-17
First Post:
2010-01-20
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Glycemic Index and Polyphenol Bioavailability of Potatoes
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003920', 'term': 'Diabetes Mellitus'}, {'id': 'D007333', 'term': 'Insulin Resistance'}], 'ancestors': [{'id': 'D044882', 'term': 'Glucose Metabolism Disorders'}, {'id': 'D008659', 'term': 'Metabolic Diseases'}, {'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}, {'id': 'D004700', 'term': 'Endocrine System Diseases'}, {'id': 'D006946', 'term': 'Hyperinsulinism'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'BASIC_SCIENCE', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 10}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2010-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2011-01', 'completionDateStruct': {'date': '2010-03', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2011-01-14', 'studyFirstSubmitDate': '2010-01-20', 'studyFirstSubmitQcDate': '2010-01-20', 'lastUpdatePostDateStruct': {'date': '2011-01-17', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2010-01-21', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2010-02', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Glycemic response', 'timeFrame': '2 hrs'}], 'secondaryOutcomes': [{'measure': 'Bioavailability of polyphenols from potatoes', 'timeFrame': '4 hours'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['Glycemic index', 'Anthocyanin', 'Potato', 'Polyphenol'], 'conditions': ['Diabetes', 'Insulin Resistance']}, 'referencesModule': {'references': [{'pmid': '18175765', 'type': 'BACKGROUND', 'citation': 'Wolever TM, Brand-Miller JC, Abernethy J, Astrup A, Atkinson F, Axelsen M, Bjorck I, Brighenti F, Brown R, Brynes A, Casiraghi MC, Cazaubiel M, Dahlqvist L, Delport E, Denyer GS, Erba D, Frost G, Granfeldt Y, Hampton S, Hart VA, Hatonen KA, Henry CJ, Hertzler S, Hull S, Jerling J, Johnston KL, Lightowler H, Mann N, Morgan L, Panlasigui LN, Pelkman C, Perry T, Pfeiffer AF, Pieters M, Ramdath DD, Ramsingh RT, Robert SD, Robinson C, Sarkkinen E, Scazzina F, Sison DC, Sloth B, Staniforth J, Tapola N, Valsta LM, Verkooijen I, Weickert MO, Weseler AR, Wilkie P, Zhang J. Measuring the glycemic index of foods: interlaboratory study. Am J Clin Nutr. 2008 Jan;87(1):247S-257S. doi: 10.1093/ajcn/87.1.247S.'}, {'pmid': '15182400', 'type': 'BACKGROUND', 'citation': 'Ramdath DD, Isaacs RL, Teelucksingh S, Wolever TM. Glycaemic index of selected staples commonly eaten in the Caribbean and the effects of boiling v. crushing. Br J Nutr. 2004 Jun;91(6):971-7. doi: 10.1079/bjn20041125.'}, {'pmid': '12627186', 'type': 'BACKGROUND', 'citation': 'Wolever TM, Vorster HH, Bjorck I, Brand-Miller J, Brighenti F, Mann JI, Ramdath DD, Granfeldt Y, Holt S, Perry TL, Venter C, Xiaomei Wu. Determination of the glycaemic index of foods: interlaboratory study. Eur J Clin Nutr. 2003 Mar;57(3):475-82. doi: 10.1038/sj.ejcn.1601551.'}, {'pmid': '12090025', 'type': 'BACKGROUND', 'citation': 'Wolever TM, Isaacs RL, Ramdath DD. Lower diet glycaemic index in African than South Asian men in Trinidad and Tobago. Int J Food Sci Nutr. 2002 Jul;53(4):297-303. doi: 10.1080/09637480220138142.'}]}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.', 'detailedDescription': 'Ten healthy persons will have a fasting blood sample drawn and asked to randomly consume a 50g glucose drink (2 occasions), or 50g carbohydrate equivalent of cooked purple, red, yellow and white potatoes. Further blood samples will be obtained at 15,30, 45, 60, 90, 120, 180, 240 mins. Bloods from the first 2 hours will be analyzed for glucose and insulin to determine the glycemic response. Hourly blood samples will be analyzed for polyphenol to determine the bioavailability of polyphenols from the different potato variety. Urine samples will be collected before ingestion of the food items and again at 4 hours, and will be used to determine polyphenol bioavailability.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '50 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* healthy, non-smoker on no medication\n* normal glucose tolerance\n* willing to have a catheter inserted in forearm\n\nExclusion Criteria:\n\n* abnormal glucose tolerance\n* abnormal BMI\n* on medication for a chronic disorder'}, 'identificationModule': {'nctId': 'NCT01053793', 'acronym': 'GI', 'briefTitle': 'Glycemic Index and Polyphenol Bioavailability of Potatoes', 'organization': {'class': 'OTHER_GOV', 'fullName': 'Guelph Food Research Centre'}, 'officialTitle': 'A Trial to Measure the Glycemic Index and Polyphenol Bioavailability of Four Different Varieties of Potato.', 'orgStudyIdInfo': {'id': '09-11-004'}, 'secondaryIdInfos': [{'id': 'GFRC 09-11-004', 'type': 'OTHER', 'domain': 'Canadian Shield'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'Glucose Standard', 'interventionNames': ['Other: Glycemic response to different varieties of potatoes']}, {'type': 'EXPERIMENTAL', 'label': 'Potato Variety', 'interventionNames': ['Other: Glycemic response to different varieties of potatoes']}], 'interventions': [{'name': 'Glycemic response to different varieties of potatoes', 'type': 'OTHER', 'otherNames': ['Purple potato', 'Red potato', 'White potato', 'Yellow potaot'], 'description': 'the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard', 'armGroupLabels': ['Glucose Standard', 'Potato Variety']}]}, 'contactsLocationsModule': {'locations': [{'zip': 'N1G 0B4', 'city': 'Guelph', 'state': 'Ontario', 'country': 'Canada', 'facility': 'Nutrasource Diagnostic Inc', 'geoPoint': {'lat': 43.54594, 'lon': -80.25599}}], 'overallOfficials': [{'name': 'Dan Ramdath, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Agriculture and Agri-Food Canada'}, {'name': 'Maggie Laidlaw, PhD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Nutracource Diagnostics Inc'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Guelph Food Research Centre', 'class': 'OTHER_GOV'}, 'collaborators': [{'name': 'Nutrasource Pharmaceutical and Nutraceutical Services, Inc.', 'class': 'NETWORK'}], 'responsibleParty': {'oldNameTitle': 'Dr. Dan Ramdath - Research Scientist', 'oldOrganization': 'Agriculture and Agri-Food Canada - Guelph Food Research Centre'}}}}