Ignite Creation Date:
2025-12-25 @ 1:21 AM
Ignite Modification Date:
2026-01-04 @ 3:43 AM
Study NCT ID:
NCT03053193
Status:
RECRUITING
Last Update Posted:
2025-08-20
First Post:
2017-02-09
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D001943', 'term': 'Breast Neoplasms'}], 'ancestors': [{'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D001941', 'term': 'Breast Diseases'}, {'id': 'D012871', 'term': 'Skin Diseases'}, {'id': 'D017437', 'term': 'Skin and Connective Tissue Diseases'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'Tumor tissue acquired as part of a standard of care biopsy or surgical procedure will be sent to Agendia for testing.'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 30000}, 'targetDuration': '10 Years', 'patientRegistry': True}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2017-04-28', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-08', 'completionDateStruct': {'date': '2037-12', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-08-15', 'studyFirstSubmitDate': '2017-02-09', 'studyFirstSubmitQcDate': '2017-02-10', 'lastUpdatePostDateStruct': {'date': '2025-08-20', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2017-02-15', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2037-04', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'A large scale registry of full genome expression data to investigate new gene associations with prognostic and/or predictive value will be created.', 'timeFrame': '10 years', 'description': 'Create a large scale registry of full genome expression data with clinical data to investigate possible new gene associations with prognostic or predictive value.'}, {'measure': 'A shared registry infrastructure to examine smaller groups of interest.', 'timeFrame': '10 years', 'description': 'Create a shared registry infrastructure to examine smaller groups of interest.'}], 'secondaryOutcomes': [{'measure': 'Subset analyses based on full genome data will be created.', 'timeFrame': '10 years', 'description': 'Use full genome data to analyze subsets.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['breast cancer', 'stage I', 'stage II', 'stage III'], 'conditions': ['Breast Cancer']}, 'referencesModule': {'references': [{'pmid': '40796181', 'type': 'DERIVED', 'citation': "Brufsky AM, Hoskins KF, Conter HJ, Kelemen P, Habibi M, Samian L, Rahman RL, Lee L, Dias EC, Hampton R, Sieling BA, Osborne CR, Brown E, Elayoubi JA, Sharma P, Ramadurai J, Matt-Amaral L, Santillan AA, Davis S, Albaneze P, Ramaswamy H, Chmielewski-Stivers N, Menicucci A, Audeh W, Whitworth P, Johnson N, O'Shaughnessy J. MammaPrint predicts chemotherapy benefit in HR+HER2- early breast cancer: FLEX Registry real-world data. JNCI Cancer Spectr. 2025 Sep 1;9(5):pkaf079. doi: 10.1093/jncics/pkaf079."}]}, 'descriptionModule': {'briefSummary': 'The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.', 'detailedDescription': 'The FLEX Registry will include all patients with stage I-III breast cancer who have received MammaPrint and BluePrint testing in any clinical setting. Study arm appendices will specify treatment arm, inclusion criteria, and number of patients needed. Approximately 30,000 patients from 125+ US based institutions will be enrolled.\n\nTreatment is at the discretion of the physician adhering to NCCN approved regimens of a recognized alternative.\n\nClinical data will be collected and entered online at the time points listed: patient enrollment, time of treatment, 1 year post-treatment, and 3, 5, and 10 years post diagnosis.\n\nObjectives:\n\n* Create a large scale, population-based registry of full genome expression data and clinical data to investigate new gene associations with prognostic and/or predictive value\n* Utilize shared registry infrastructure to examine smaller groups of interest\n* Generate hypotheses for targeted subset analyses and trials based on full genome data\n\nFLEX is an observational (phase IV) study.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Study population will include patients with stage I, II, or III breast cancer that have signed an informed consent, and are eligible to receive chemotherapy and endocrine therapy. Patients will be excluded if they have metastatic disease or do not have ample tissue to send to Agendia for testing.', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Stage I, II, or III patients who receive MammaPrint, with or without BluePrint testing (male or female)\n* Informed consent form signed on the same day or before enrollment\n* New primary lesion\n\nExclusion Criteria:\n\n* Tumor sample shipped to Agendia with ≤ 30% tumor cells or that fails QA or QC criteria\n* Metastatic disease\n* Recurrent disease\n* Stage 0 disease'}, 'identificationModule': {'nctId': 'NCT03053193', 'acronym': 'FLEX', 'briefTitle': 'MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles', 'organization': {'class': 'INDUSTRY', 'fullName': 'Agendia'}, 'officialTitle': 'MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles: An Adaptable Registry (FLEX)', 'orgStudyIdInfo': {'id': 'FLEX Registry'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'MammaPrint and BluePrint testing', 'description': 'All patients will receive MammaPrint and BluePrint testing using the full-genome testing data chip. Treatment will be at the discretion of the physician while adhering to NCCN guidelines.', 'interventionNames': ['Diagnostic Test: MammaPrint, BluePrint, and Full-Genome Testing']}], 'interventions': [{'name': 'MammaPrint, BluePrint, and Full-Genome Testing', 'type': 'DIAGNOSTIC_TEST', 'otherNames': ['MammaPrint, BluePrint'], 'description': 'Agendia will run MammaPrint and BluePrint tests using the full genome testing array.', 'armGroupLabels': ['MammaPrint and BluePrint testing']}]}, 'contactsLocationsModule': {'locations': [{'zip': '35243', 'city': 'Birmingham', 'state': 'Alabama', 'status': 'COMPLETED', 'country': 'United States', 'facility': 'CHS Grandview', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '99508', 'city': 'Anchorage', 'state': 'Alaska', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Nicolette Ziolkowski', 'role': 'CONTACT', 'email': 'NicoletteAnne.Ziolkowski@providence.org'}, {'name': 'Theodore Kim', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Providence Alaska Medical Center', 'geoPoint': {'lat': 61.21806, 'lon': -149.90028}}, {'zip': '85006', 'city': 'Phoenix', 'state': 'Arizona', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jeanette Cardenas', 'role': 'CONTACT', 'email': 'Jeanette.Cardenas@usoncology.com'}, {'name': 'Rachel Swart', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Arizona Oncology Associates, PC', 'geoPoint': {'lat': 33.44838, 'lon': -112.07404}}, {'zip': '85704', 'city': 'Tucson', 'state': 'Arizona', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Julie Klinker', 'role': 'CONTACT', 'email': 'julie.klinker@usoncology.com'}, {'name': 'Rachel Swart, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Arizona Oncology Associates, PC - HOPE', 'geoPoint': {'lat': 32.22174, 'lon': -110.92648}}, {'zip': '93301', 'city': 'Bakersfield', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Nicole Gordon', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Adventist Health - Bakersfield', 'geoPoint': {'lat': 35.37329, 'lon': -119.01871}}, {'zip': '92262', 'city': 'Palm Springs', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Claudia Fortiche', 'role': 'CONTACT', 'email': 'claudia.fortiche@tenethealth.com'}, {'name': 'Laura Lee, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Comprehensive Cancer Center at Desert Regional Medical Center', 'geoPoint': {'lat': 33.8303, 'lon': -116.54529}}, {'zip': '96001', 'city': 'Redding', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Ian Grady, MD', 'role': 'CONTACT', 'phone': '530-243-5551'}, {'name': 'Ian P Grady, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'North Valley Breast Clinic', 'geoPoint': {'lat': 40.58654, 'lon': -122.39168}}, {'zip': '94158', 'city': 'San Francisco', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Molly Baxter', 'role': 'CONTACT', 'email': 'molly.baxter@ucsf.edu'}, {'name': 'Rita Mukhtar, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}, {'name': 'Laura Esserman, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'UCSF Breast Care Center', 'geoPoint': {'lat': 37.77493, 'lon': -122.41942}}, {'zip': '91405', 'city': 'Van Nuys', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'James Dunham', 'role': 'CONTACT', 'email': 'james@valleybreastcare.org'}, {'name': 'Thomas Lomis, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Valley Breast Care', 'geoPoint': {'lat': 34.18667, 'lon': -118.44897}}, {'zip': '80012', 'city': 'Aurora', 'state': 'Colorado', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Wafa El-Ejmi', 'role': 'CONTACT', 'email': 'wafa.el-ejmi@usoncology.com'}, {'name': 'Sami Diab, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Rocky Mountain Cancer Centers', 'geoPoint': {'lat': 39.72943, 'lon': -104.83192}}, {'zip': '80045', 'city': 'Aurora', 'state': 'Colorado', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Julia LeBlanc', 'role': 'CONTACT', 'email': 'julia.leblanc@cuanschutz.edu'}, {'name': 'Virginia Borges, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Colorado Cancer Center', 'geoPoint': {'lat': 39.72943, 'lon': -104.83192}}, {'zip': '80218', 'city': 'Denver', 'state': 'Colorado', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Joseph Ruybal, MA', 'role': 'CONTACT', 'email': 'Joseph.Ruybal@sclhs.net'}, {'name': 'Julie Barone, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Comprehensive Breast Care of Denver', 'geoPoint': {'lat': 39.73915, 'lon': -104.9847}}, {'zip': '80228', 'city': 'Lakewood', 'state': 'Colorado', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Sami Diab, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Rocky Mountain Cancer Center - Lakewood', 'geoPoint': {'lat': 39.70471, 'lon': -105.08137}}, {'zip': '81658', 'city': 'Vail', 'state': 'Colorado', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Paige Bordelon', 'role': 'CONTACT', 'email': 'paige.bordelon@vailhealth.org'}, {'name': 'Julie Barone, DO', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Vail Health - Shaw Cancer Center', 'geoPoint': {'lat': 39.64026, 'lon': -106.3742}}, {'zip': '06706', 'city': 'Waterbury', 'state': 'Connecticut', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jessica Bello', 'role': 'CONTACT', 'email': 'Jessica.Bello@TrinityHealthOfNE.org'}, {'name': 'Beth Sieling, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "St. Mary's Hospital", 'geoPoint': {'lat': 41.55815, 'lon': -73.0515}}, {'zip': '19713', 'city': 'Newark', 'state': 'Delaware', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Julie Yucis', 'role': 'CONTACT', 'email': 'Julie.Yucis@usoncology.com'}, {'name': 'Jamal Misleh, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Medical Oncology and Hematology Consultants', 'geoPoint': {'lat': 39.68372, 'lon': -75.74966}}, {'zip': '33462', 'city': 'Atlantis', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Taylor Stroud', 'role': 'CONTACT', 'email': 'taylor.stroud@sflbreastcare.com'}, {'name': 'June Lee, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Breast Specialists of South Florida', 'geoPoint': {'lat': 26.5909, 'lon': -80.10088}}, {'zip': '33462', 'city': 'Atlantis', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Tonnica Sasanas, RN, BSN', 'role': 'CONTACT', 'email': 'Tonnica.Sasanas@hcahealthcare.com', 'phone': '561-548-1877'}, {'name': 'Julian Berrocal, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'JFK Medical Center', 'geoPoint': {'lat': 26.5909, 'lon': -80.10088}}, {'zip': '33428', 'city': 'Boca Raton', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Maggie Szymczak', 'role': 'CONTACT', 'email': 'mszymczak@brrh.com'}, {'name': 'Jane Skelton, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Boca Raton Regional Hospital', 'geoPoint': {'lat': 26.35869, 'lon': -80.0831}}, {'zip': '33756', 'city': 'Clearwater', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Mindy Thacker, B.S.', 'role': 'CONTACT', 'email': 'Mindy.Thacker@baycare.org', 'phone': '727-298-6190'}, {'name': 'Peter Blumencranz, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Morton Plant Hospital', 'geoPoint': {'lat': 27.96585, 'lon': -82.8001}}, {'zip': '32114', 'city': 'Daytona Beach', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Deborah Reynolds', 'role': 'CONTACT', 'email': 'debbie.reynolds@halifax.org'}, {'name': 'Ruby Anne Deveras, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Halifax Health - Center for Oncology', 'geoPoint': {'lat': 29.21081, 'lon': -81.02283}}, {'zip': '32207', 'city': 'Jacksonville', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Colleen Rosentraub', 'role': 'CONTACT', 'email': 'Colleen.Rosentraub@bmcjax.com', 'phone': '904-202-7085'}, {'name': 'Jennifer Crozier, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Baptist MD Anderson Cancer Center', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '32224', 'city': 'Jacksonville', 'state': 'Florida', 'status': 'COMPLETED', 'country': 'United States', 'facility': 'University of Florida - Jacksonville', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '32256', 'city': 'Jacksonville', 'state': 'Florida', 'status': 'ACTIVE_NOT_RECRUITING', 'country': 'United States', 'facility': 'St. Vincent Hospital / Mayo Clinic', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '33805', 'city': 'Lakeland', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Rebecca Delph', 'role': 'CONTACT', 'email': 'Rebecca.Delph@myLRH.org'}, {'name': 'Madhavi Venigalla, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Lakeland Regional Cancer Center', 'geoPoint': {'lat': 28.03947, 'lon': -81.9498}}, {'zip': '33136', 'city': 'Miami', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Teresa Torres', 'role': 'CONTACT', 'email': 'otorres@miami.edu'}, {'name': 'Reshma L Mahtani, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Sylvester Comprehensive Cancer Center - University of Miami', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '33176', 'city': 'Miami', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Elaine Hernandez', 'role': 'CONTACT', 'email': 'ElaineHer@baptisthealth.net'}, {'name': 'Lauren Carcas', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Miami Cancer Institute at Baptist Health, Inc', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '32955', 'city': 'Rockledge', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Deborah Schmitt', 'role': 'CONTACT', 'email': 'deborah.schmitt@usoncology.com'}, {'name': 'Pavan Kancharla, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Cancer Care Centers of Brevard', 'geoPoint': {'lat': 28.35084, 'lon': -80.72533}}, {'zip': '33607', 'city': 'Tampa', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Lyn Shelley-velez, RN', 'role': 'CONTACT', 'email': 'Lyn.Shelley-velez@baycare.org', 'phone': '813-356-7144'}, {'name': 'Robert Gabordi, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "St. Joseph's Hospital - Baycare", 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '33613', 'city': 'Tampa', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': "Al'Lima Trotman", 'role': 'CONTACT', 'email': 'atrotman1@usf.edu', 'phone': '813-660-6158'}, {'name': 'Charles Cox, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of South Florida', 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '33881', 'city': 'Winter Haven', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Sharhonda Davis, RN', 'role': 'CONTACT', 'email': 'Sharhonda.Davis@BAYCARE.ORG', 'phone': '863-293-1121', 'phoneExt': '205872'}, {'name': 'Kamal Sharma, DO', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Winter Haven Hospital', 'geoPoint': {'lat': 28.02224, 'lon': -81.73286}}, {'zip': '31701', 'city': 'Albany', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Keisa Mansfield', 'role': 'CONTACT', 'email': 'kmansfield@phoebehealth.com', 'phone': '229-312-5091'}, {'name': 'Penny Robinson, RN', 'role': 'CONTACT', 'email': 'penrobin@phoebehealth.com', 'phone': '229-312-5703'}, {'name': 'Chirag Jani, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Phoebe Health', 'geoPoint': {'lat': 31.57851, 'lon': -84.15574}}, {'zip': '30318', 'city': 'Atlanta', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Olabusola Awoyemi, RN, BSN, MPH', 'role': 'CONTACT', 'email': 'OAwoyemi@piedmontcancerinstitute.com', 'phone': '678-298-3242'}, {'name': 'Trevor Feinstein, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Piedmont Cancer Institute', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}, {'zip': '30322', 'city': 'Atlanta', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Alicia Escobar', 'role': 'CONTACT', 'email': 'alicia.m.escobar@emory.edu'}, {'name': 'Cathy Graham, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Emory University - Winship Cancer Institute', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}, {'zip': '31520', 'city': 'Brunswick', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'William L Tillett, PharmD', 'role': 'CONTACT', 'email': 'wtillet@sghs.org', 'phone': '912-466-5363'}, {'name': 'Abraham Cheong, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Southeast Georgia Health System - Physician Associates', 'geoPoint': {'lat': 31.15013, 'lon': -81.49147}}, {'zip': '30033', 'city': 'Decatur', 'state': 'Georgia', 'status': 'COMPLETED', 'country': 'United States', 'facility': 'DeKalb Medical Center', 'geoPoint': {'lat': 33.77483, 'lon': -84.29631}}, {'zip': '31405', 'city': 'Savannah', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Catherine Ronaghan', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Candler Hospital', 'geoPoint': {'lat': 32.08354, 'lon': -81.09983}}, {'zip': '31794', 'city': 'Tifton', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jodie Davis, RN', 'role': 'CONTACT', 'email': 'Jodie.Davis@tiftregional.com', 'phone': '229-353-3730'}, {'name': 'Apurva Shah, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Tift Regional Health System', 'geoPoint': {'lat': 31.45046, 'lon': -83.5085}}, {'zip': '60612', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Darlene Kitterman', 'role': 'CONTACT', 'email': 'dkitt@uic.edu'}, {'name': 'VK Gadi, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Illinois at Chicago', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '60007', 'city': 'Elk Grove Village', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Lauren Niklinski', 'role': 'CONTACT', 'email': 'Lauren.Niklinski@AMITAhealth.org'}, {'name': 'Robert Maganini, MD', 'role': 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