Ignite Creation Date:
2025-12-25 @ 1:19 AM
Ignite Modification Date:
2025-12-25 @ 11:28 PM
Study NCT ID:
NCT01311193
Status:
COMPLETED
Last Update Posted:
2011-03-09
First Post:
2011-03-03
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D001883', 'term': 'Borderline Personality Disorder'}, {'id': 'D020447', 'term': 'Parasomnias'}, {'id': 'D003863', 'term': 'Depression'}], 'ancestors': [{'id': 'D010554', 'term': 'Personality Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}, {'id': 'D012893', 'term': 'Sleep Wake Disorders'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D001526', 'term': 'Behavioral Symptoms'}, {'id': 'D001519', 'term': 'Behavior'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D010789', 'term': 'Phototherapy'}], 'ancestors': [{'id': 'D013812', 'term': 'Therapeutics'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL'}, 'statusModule': {'overallStatus': 'COMPLETED', 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2011-03', 'lastUpdateSubmitDate': '2011-03-07', 'studyFirstSubmitDate': '2011-03-03', 'studyFirstSubmitQcDate': '2011-03-07', 'lastUpdatePostDateStruct': {'date': '2011-03-09', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2011-03-09', 'type': 'ESTIMATED'}}, 'conditionsModule': {'keywords': ['Circadian rhythms', 'Sleep-wake cycles', 'Melatonin', 'Borderline Personality Disorder', 'Light therapy'], 'conditions': ['Borderline Personality Disorder', 'Sleep Disturbances', 'Depression']}, 'referencesModule': {'seeAlsoLinks': [{'url': 'http://www.chronobiology.ch', 'label': 'Related Info'}]}, 'descriptionModule': {'briefSummary': 'Individuals with borderline personality disorder (BPD) frequently suffer from emotional instability, daytime fatigue and sleep disturbances. The investigators examined circadian rhythms, sleep and well-being in women with BPD under their habitual life conditions with and without light treatment.\n\nTreated women diagnosed with BPD were investigated during 3 weeks without and 3 weeks with morning LT. Rest-activity cycles were continuously measured using wrist actigraphy, together with proximal skin temperature. Saliva samples were collected weekly to determine the diurnal melatonin rhythm. A range of self-ratings and questionnaires were used to assess depression and clinical state throughout the 6-week protocol. Ten matched healthy women followed the same 6-week protocol without light treatment.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT'], 'maximumAge': '45 Years', 'minimumAge': '20 Years', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Borderline Personality Disorder (DSM IV-criteria)\n* German-speaking\n* normal ocular function\n\nExclusion Criteria:\n\n* lack of compliance'}, 'identificationModule': {'nctId': 'NCT01311193', 'briefTitle': 'Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder', 'organization': {'class': 'OTHER', 'fullName': 'University Hospital, Basel, Switzerland'}, 'officialTitle': 'Circadian Sleep-wake Cycles, Well-being and Light Therapy in Borderline Personality Disorder', 'orgStudyIdInfo': {'id': 'Velux-425'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'light therapy', 'description': 'Morning bright light treatment (at 8000 lux for 40min, daily during 3 weeks)', 'interventionNames': ['Other: light therapy']}], 'interventions': [{'name': 'light therapy', 'type': 'OTHER', 'description': 'early morning exposures to bright light, 8000lux for 40min, daily during 3 weeks', 'armGroupLabels': ['light therapy']}]}, 'contactsLocationsModule': {'locations': [{'zip': '4012', 'city': 'Basel', 'state': 'Canton of Basel-City', 'country': 'Switzerland', 'facility': 'Centre for Chronobiology, Psychiatric Hospital, University of Basel', 'geoPoint': {'lat': 47.55839, 'lon': 7.57327}}], 'overallOfficials': [{'name': 'Christian Cajochen, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Centre for Chronobiology, Psychiatric Hospital, University of Basel'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital, Basel, Switzerland', 'class': 'OTHER'}, 'collaborators': [{'name': 'Velux Fonden', 'class': 'OTHER'}, {'name': 'Lumie UK', 'class': 'UNKNOWN'}]}}}