Ignite Creation Date:
2025-12-25 @ 1:06 AM
Ignite Modification Date:
2025-12-27 @ 3:06 AM
Study NCT ID:
NCT00463593
Status:
COMPLETED
Last Update Posted:
2008-01-25
First Post:
2007-04-19
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control Programmes
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D012552', 'term': 'Schistosomiasis'}, {'id': 'D006373', 'term': 'Helminthiasis'}, {'id': 'D000740', 'term': 'Anemia'}], 'ancestors': [{'id': 'D014201', 'term': 'Trematode Infections'}, {'id': 'D010272', 'term': 'Parasitic Diseases'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D000079426', 'term': 'Vector Borne Diseases'}, {'id': 'D006402', 'term': 'Hematologic Diseases'}, {'id': 'D006425', 'term': 'Hemic and Lymphatic Diseases'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'NONE_RETAINED', 'description': 'faeces blood'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 1293}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2006-12'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2008-01', 'completionDateStruct': {'date': '2007-06', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2008-01-23', 'studyFirstSubmitDate': '2007-04-19', 'studyFirstSubmitQcDate': '2007-04-19', 'lastUpdatePostDateStruct': {'date': '2008-01-25', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2007-04-20', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['schistosomiasis', 'helminthes', 'anaemia'], 'conditions': ['Schistosomiasis', 'Helminthiasis', 'Anaemia']}, 'descriptionModule': {'briefSummary': 'Current efforts to control schistosomiasis and soil-transmitted helminthes infections focus on the school-age population, and school-based treatment delivery programs offer a major cost advantages because of the use of the existing school infrastructure and the fact that schoolchildren are accessible through schools. However, in many developing countries, large numbers of school-age children are not in school and this has raised questions about the effectiveness of school-based programs in reaching non-enrolled children. Increasingly, the non-formal education sector is providing a growing solution to the problem of poor enrolment in basic education, especially in sub-Saharan Africa, and has recently been used to deliver praziquantel as part of a national schistosomiasis control program in Uganda. However, it is unclear how effective this program has been in reaching children who attend non-formal schools and whether the program has been reaching children from the poorest households.', 'detailedDescription': 'This study will compare infection and nutritional status of children enrolled in formal schools and non-formal schools, and non-enrolled children in Nakasongola District in Uganda, and investigate the process and impact of treatment delivered by the national control program. The study will consist of household surveys and cross-sectional parasitological and hematological surveys, with follow-up six months later. The evaluation will take place over the course of a year and will:\n\n* Compare the infection and nutritional status of children enrolled in formal schools and non-formal schools, and non-enrolled children in Nakasongola District, Uganda\n* Compare programmatic process indicators, including enrolment rates, attendance rates, access to water and sanitation, treatment coverage in formal and non-formal schools\n* Investigate the impact of treatment on intensity of infection and reinfection rates in formal and non-formal schools.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT'], 'maximumAge': '18 Years', 'minimumAge': '6 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'children enrolled in formal schools and children not enrolled in formal school identified by household survey', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* School children in grad 1 and 2'}, 'identificationModule': {'nctId': 'NCT00463593', 'briefTitle': 'Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control Programmes', 'organization': {'class': 'OTHER', 'fullName': 'DBL -Institute for Health Research and Development'}, 'officialTitle': 'Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control', 'orgStudyIdInfo': {'id': 'SRP-UG-NK-06'}}, 'armsInterventionsModule': {'armGroups': [{'label': '2', 'description': 'children enrolled in formal schools and children not enrolled in formal schools'}]}, 'contactsLocationsModule': {'locations': [{'city': 'Kampala', 'country': 'Uganda', 'facility': 'Vector Control Division', 'geoPoint': {'lat': 0.31628, 'lon': 32.58219}}], 'overallOfficials': [{'name': 'Narcis Kabatereine, Dr', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Vector Control Division, Ministry of Health Uganda'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'DBL -Institute for Health Research and Development', 'class': 'OTHER'}}}}