Ignite Creation Date:
2025-12-25 @ 12:33 AM
Ignite Modification Date:
2026-02-23 @ 2:24 AM
Study NCT ID:
NCT01255267
Status:
UNKNOWN
Last Update Posted:
2010-12-07
First Post:
2010-12-06
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Correlation Between Genetic Polymorphism, Platelet Activity, Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D054058', 'term': 'Acute Coronary Syndrome'}], 'ancestors': [{'id': 'D017202', 'term': 'Myocardial Ischemia'}, {'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2010-12', 'lastUpdateSubmitDate': '2010-12-06', 'studyFirstSubmitDate': '2010-12-06', 'studyFirstSubmitQcDate': '2010-12-06', 'lastUpdatePostDateStruct': {'date': '2010-12-07', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2010-12-07', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['Acute coronary syndrome and chronic coronary artery disease patients'], 'conditions': ['Acute Coronary Syndrome', 'Chronic Coronary Artery Disease']}, 'descriptionModule': {'briefSummary': 'In this study, we evaluate the acute coronary syndrome patients to see if there is correlation between platelet activity, genetic polymorphism (CYP2C19 and ABCB1), serum adipokines level, and Clopidogrel responsiveness.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Acute coronary syndrome and chronic coronary artery diseae patients', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Age \\> 18 y/o\n2. Acute coronary syndrome patients\n3. Chronic coronary artery disease patients\n4. Healthy volunteers\n\nExclusion Criteria:\n\n1. Patient refusal\n2. Allergy to Clopidogrel\n3. Receive Gp IIb/IIIa inhibitor simultaneously\n4. Cancer history\n5. Severe renal and liver function impairment\n6. Coagulopathy'}, 'identificationModule': {'nctId': 'NCT01255267', 'briefTitle': 'The Correlation Between Genetic Polymorphism, Platelet Activity, Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients', 'organization': {'class': 'OTHER', 'fullName': 'China Medical University Hospital'}, 'officialTitle': 'The Correlation Between Genetic Polymorphism, Platelet Activity, , Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients', 'orgStudyIdInfo': {'id': 'DMR99-IRB-041'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Acute coronary syndrome patients'}, {'label': 'Chronic coronary artery disease patients'}, {'label': 'Healthy control'}]}, 'contactsLocationsModule': {'locations': [{'city': 'Taichung', 'status': 'RECRUITING', 'country': 'Taiwan', 'contacts': [{'name': 'Yu-Chen Wang, MD', 'role': 'CONTACT', 'email': 'richard9250@yahoo.com.tw', 'phone': '886-4-22052121', 'phoneExt': '2371'}], 'facility': 'China Medical University Hospital', 'geoPoint': {'lat': 24.1469, 'lon': 120.6839}}], 'centralContacts': [{'name': 'Yu-Chen Wang, MD', 'role': 'CONTACT', 'email': 'richard9250@yahoo.com.tw', 'phone': '886-4-22052121', 'phoneExt': '2371'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'China Medical University Hospital', 'class': 'OTHER'}}}}