Ignite Creation Date:
2025-12-25 @ 12:14 AM
Ignite Modification Date:
2025-12-25 @ 10:16 PM
Study NCT ID:
NCT00442858
Status:
COMPLETED
Last Update Posted:
2007-03-05
First Post:
2007-03-01
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Incidence of Cardiovascular Diseases in Patients With Hypopituitarims
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002561', 'term': 'Cerebrovascular Disorders'}, {'id': 'D004393', 'term': 'Dwarfism, Pituitary'}, {'id': 'D003920', 'term': 'Diabetes Mellitus'}, {'id': 'D006973', 'term': 'Hypertension'}], 'ancestors': [{'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D004392', 'term': 'Dwarfism'}, {'id': 'D001848', 'term': 'Bone Diseases, Developmental'}, {'id': 'D001847', 'term': 'Bone Diseases'}, {'id': 'D009140', 'term': 'Musculoskeletal Diseases'}, {'id': 'D001849', 'term': 'Bone Diseases, Endocrine'}, {'id': 'D007018', 'term': 'Hypopituitarism'}, {'id': 'D010900', 'term': 'Pituitary Diseases'}, {'id': 'D007027', 'term': 'Hypothalamic Diseases'}, {'id': 'D004700', 'term': 'Endocrine System Diseases'}, {'id': 'D044882', 'term': 'Glucose Metabolism Disorders'}, {'id': 'D008659', 'term': 'Metabolic Diseases'}, {'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'DEFINED_POPULATION'}, 'enrollmentInfo': {'count': 800}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '1999-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2007-03', 'completionDateStruct': {'date': '2002-12'}, 'lastUpdateSubmitDate': '2007-03-01', 'studyFirstSubmitDate': '2007-03-01', 'studyFirstSubmitQcDate': '2007-03-01', 'lastUpdatePostDateStruct': {'date': '2007-03-05', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2007-03-05', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['cardiac disease', 'cerebrovascular disease', 'GH deficiency', 'diabetes mellitus', 'hypertension', 'GH therapy', 'GH deficiency and hypopituitarims'], 'conditions': ['Cardiovascular Diseases']}, 'descriptionModule': {'briefSummary': 'The aim of the present study was therefore two-fold: 1) to make a retrospective comparison of incidence of non-fatal stroke and cardiac events between a large cohort of patients with confirmed GHD on replacement therapy (including GH) and a control cohort from the general population; 2) to compare the prevalence of DM and cardioprotective medication between the cohorts at the time of questionnaire distribution with adjustment for possible confounders and effect modifiers.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Confirmed GH deficiency\n\nExclusion Criteria:\n\n* Not confirmed GH deficiency'}, 'identificationModule': {'nctId': 'NCT00442858', 'briefTitle': 'Incidence of Cardiovascular Diseases in Patients With Hypopituitarims', 'organization': {'class': 'OTHER', 'fullName': 'Lund University Hospital'}, 'orgStudyIdInfo': {'id': 'LU-286-99'}}, 'contactsLocationsModule': {'overallOfficials': [{'name': 'Eva Marie T Erfurth, MD, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Endocrine Unit, Department of Medicine, University Hospital, Lund'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Lund University Hospital', 'class': 'OTHER'}}}}