Ignite Creation Date:
2025-12-24 @ 11:55 AM
Ignite Modification Date:
2025-12-29 @ 1:04 AM
Study NCT ID:
NCT00246961
Status:
COMPLETED
Last Update Posted:
2007-10-12
First Post:
2005-10-31
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Arimidex Observational: Reason for and Effect of Change From Tamoxifen
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D001943', 'term': 'Breast Neoplasms'}], 'ancestors': [{'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D001941', 'term': 'Breast Diseases'}, {'id': 'D012871', 'term': 'Skin Diseases'}, {'id': 'D017437', 'term': 'Skin and Connective Tissue Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE'}, 'enrollmentInfo': {'count': 200}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2004-07'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2007-06', 'lastUpdateSubmitDate': '2007-10-11', 'studyFirstSubmitDate': '2005-10-31', 'studyFirstSubmitQcDate': '2005-10-31', 'lastUpdatePostDateStruct': {'date': '2007-10-12', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2005-11-01', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Adjuvant'], 'conditions': ['Breast Cancer']}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to analyse the effect on quality of life after 3 months of treatment after changing adjuvant therapy from tamoxifen to Arimidex.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Postmenopausal\n* Hormone sensitive breast cancer\n* Patient uses tamoxifen or has stopped taking tamoxifen less than 7 days ago\n\nExclusion Criteria:\n\n* Visceral metastases\n* Patients with signs of progression at the moment of changing therapy\n* Patients who have used other endocrine treatments for breast cancer besides tamoxifen'}, 'identificationModule': {'nctId': 'NCT00246961', 'acronym': 'ARREST', 'briefTitle': 'Arimidex Observational: Reason for and Effect of Change From Tamoxifen', 'organization': {'class': 'INDUSTRY', 'fullName': 'AstraZeneca'}, 'officialTitle': 'Arimidex: Reason for and Effect of Change From Tamoxifen', 'orgStudyIdInfo': {'id': 'D5392NL0002'}, 'secondaryIdInfos': [{'id': 'ARREST'}]}, 'contactsLocationsModule': {'locations': [{'city': "'s-Hertogenbosch", 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.69917, 'lon': 5.30417}}, {'city': 'Alkmaar', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.63167, 'lon': 4.74861}}, {'city': 'Antwerpen', 'country': 'Netherlands', 'facility': 'Research Site'}, {'city': 'Apeldoorn', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.21, 'lon': 5.96944}}, {'city': 'Bergen op Zoom', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.495, 'lon': 4.29167}}, {'city': 'Boxmeer', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.64667, 'lon': 5.94722}}, {'city': 'Breda', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.58656, 'lon': 4.77596}}, {'city': 'Doetinchem', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.965, 'lon': 6.28889}}, {'city': 'Dordrecht', 'country': 'Netherlands', 'facility': 'Research SIte', 'geoPoint': {'lat': 51.81, 'lon': 4.67361}}, {'city': 'Ede', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.03333, 'lon': 5.65833}}, {'city': 'Eindhoven', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.44083, 'lon': 5.47778}}, {'city': 'Enschede', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.21833, 'lon': 6.89583}}, {'city': 'Flushing', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.4425, 'lon': 3.57361}}, {'city': 'Geldrop', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.42167, 'lon': 5.55972}}, {'city': 'Groningen', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 53.21917, 'lon': 6.56667}}, {'city': 'Harderwijk', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.34167, 'lon': 5.62083}}, {'city': 'Helmond', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.48167, 'lon': 5.66111}}, {'city': 'Hoogeveen', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.7225, 'lon': 6.47639}}, {'city': 'Hoorn', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.6425, 'lon': 5.05972}}, {'city': 'Leiden', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.15833, 'lon': 4.49306}}, {'city': 'Oosterhout', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.645, 'lon': 4.85972}}, {'city': 'Purmerend', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.505, 'lon': 4.95972}}, {'city': 'Roermond', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.19417, 'lon': 5.9875}}, {'city': 'Roosendaal', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.53083, 'lon': 4.46528}}, {'city': 'Rotterdam', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.9225, 'lon': 4.47917}}, {'city': 'Schiedam', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.91917, 'lon': 4.38889}}, {'city': 'Terneuzen', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.33583, 'lon': 3.82778}}, {'city': 'The Hague', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.07667, 'lon': 4.29861}}, {'city': 'Tiel', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.88667, 'lon': 5.42917}}, {'city': 'Venray', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.525, 'lon': 5.975}}, {'city': 'Winterswijk', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 51.9725, 'lon': 6.71944}}, {'city': 'Zoetermeer', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.0575, 'lon': 4.49306}}, {'city': 'Zutphen', 'country': 'Netherlands', 'facility': 'Research Site', 'geoPoint': {'lat': 52.13833, 'lon': 6.20139}}], 'overallOfficials': [{'name': 'AstraZeneca The Netherlands Medical Director, MD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'AstraZeneca'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'AstraZeneca', 'class': 'INDUSTRY'}}}}