Ignite Creation Date:
2025-12-25 @ 12:01 AM
Ignite Modification Date:
2025-12-25 @ 9:59 PM
Study NCT ID:
NCT05701358
Status:
RECRUITING
Last Update Posted:
2025-06-19
First Post:
2023-01-17
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003324', 'term': 'Coronary Artery Disease'}, {'id': 'D000072658', 'term': 'Non-ST Elevated Myocardial Infarction'}, {'id': 'D000072657', 'term': 'ST Elevation Myocardial Infarction'}], 'ancestors': [{'id': 'D003327', 'term': 'Coronary Disease'}, {'id': 'D017202', 'term': 'Myocardial Ischemia'}, {'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D001161', 'term': 'Arteriosclerosis'}, {'id': 'D001157', 'term': 'Arterial Occlusive Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D009203', 'term': 'Myocardial Infarction'}, {'id': 'D007238', 'term': 'Infarction'}, {'id': 'D007511', 'term': 'Ischemia'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D009336', 'term': 'Necrosis'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 5100}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2023-06-22', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-06', 'completionDateStruct': {'date': '2028-06', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-06-16', 'studyFirstSubmitDate': '2023-01-17', 'studyFirstSubmitQcDate': '2023-01-25', 'lastUpdatePostDateStruct': {'date': '2025-06-19', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2023-01-27', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2028-06', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Efficacy: Time to first occurrence of the composite of CV death, new MI, or IDR', 'timeFrame': 'at study completion, a minimum of 2 years'}, {'measure': 'Safety: Time to first occurrence of the composite of clinically significant bleeding, stroke, stent thrombosis, or contrast-associated acute kidney injury.', 'timeFrame': 'at study completion, a minimum of 2 years'}], 'secondaryOutcomes': [{'measure': 'Time to first occurrence of the composite of CV death or new MI.', 'timeFrame': 'at study completion, a minimum of 2 years'}, {'measure': 'Net clinical outcome: Time to first occurrence of the composite of CV death, new MI, clinically significant bleeding, stroke, stent thrombosis or contrast-associated acute kidney injury.', 'timeFrame': 'at study completion, a minimum of 2 years'}]}, 'oversightModule': {'isUsExport': False, 'oversightHasDmc': True, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['NSTEMI', 'STEMI', 'multi-vessel disease', 'optical coherence tomography', 'FFR', 'RFR', 'percutaneous coronary intervention'], 'conditions': ['Acute Myocardial Infarction', 'Coronary Artery Disease']}, 'descriptionModule': {'briefSummary': 'COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) who have undergone successful culprit lesion Percutaneous Coronary Intervention (PCI).\n\nCOMPLETE-2 OCT is a large scale, prospective, multi-centre, observational, imaging study of patients with STEMI or NSTEMI and multivessel CAD in a subset of eligible COMPLETE-2 patients.', 'detailedDescription': 'COMPLETE-2 STUDY OBJECTIVES\n\n1. To determine whether a strategy of physiology-guided complete revascularization is non-inferior to a strategy of angiography-guided complete revascularization on the efficacy composite outcome of cardiovascular (CV) death, new myocardial infarction (MI) or ischemia-driven revascularization (IDR).\n2. To determine whether a physiology-guided complete revascularization strategy is superior to an angiography-guided complete revascularization strategy in reducing the safety composite outcome of clinically significant bleeding, stroke, stent thrombosis or contrast-associated acute kidney injury.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Patients presenting with STEMI or type 1 NSTEMI and within 72 hours of successful culprit-lesion PCI\n2. Residual coronary artery disease defined as at least 1 additional non-infarct-related coronary artery stenosis that meets all of the following criteria:\n\n 1. Amenable to successful treatment with PCI\n 2. At least 50% diameter stenosis by visual estimation\n 3. At least 2.5 mm in diameter\n3. Planned complete revascularization strategy for qualifying MI\n\nExclusion Criteria:\n\n1. Planned or prior coronary artery bypass graft (CABG) surgery\n2. Inability to clearly identify a culprit lesion for STEMI or NSTEMI based on angiographic appearance and/or ECG changes and/or regional wall motion abnormalities\n3. Prior PCI of a non-culprit lesion in a different vessel from the culprit lesion within 45 days of randomization\n4. Planned medical treatment of all qualifying non-culprit lesions (i.e., no PCI)\n5. Presence of severe non-culprit-lesion stenosis with reduced epicardial flow (TIMI flow ≤ 2) or \\>90% visual diameter stenosis\n6. Presence of a chronic total occlusion (CTO) if it is the only qualifying non-culprit lesion (patients with a CTO plus additional qualifying non-culprit lesions are eligible)\n7. The only qualifying non-culprit lesion is in the same vessel territory as the culprit lesion\n8. Baseline STEMI or NSTEMI was due to a suspected non-atherothrombotic mechanism such as type 2 MI (supply-demand mismatch), including spontaneous coronary artery dissection or coronary artery embolism\n9. Non-cardiovascular co-morbidity with expected life expectancy \\<2 years\n10. Any other medical, geographic, or social factor making study participation impractical or precluding 5 year follow-up'}, 'identificationModule': {'nctId': 'NCT05701358', 'acronym': 'COMPLETE-2', 'briefTitle': 'Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease', 'organization': {'class': 'OTHER', 'fullName': 'Population Health Research Institute'}, 'officialTitle': 'A Randomized Trial of Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization Strategies & an Observational Study of Optical Coherence Tomography in Patients With Acute MI & Multivessel Coronary Artery Disease', 'orgStudyIdInfo': {'id': 'COMPLETE-2'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'Physiology-guided Non-Culprit-Lesion (NCL) PCI', 'description': 'Patients randomized to this group will have their physiology assessment using RFR and/or FFR of all qualifying NCLs that were identified prior to randomization. Other validated non-hyperemic physiology ratios (eg. iFR) may only be used when RFR is not available.', 'interventionNames': ['Procedure: Physiology-guided NCL PCI']}, {'type': 'OTHER', 'label': 'Angiography-guided NCL PCI', 'description': 'Patients randomized to this group will undergo routine staged PCI of all qualifying NCLs that were identified prior to randomization.', 'interventionNames': ['Procedure: Angiography-guided NCL PCI']}], 'interventions': [{'name': 'Physiology-guided NCL PCI', 'type': 'PROCEDURE', 'description': 'For RFR, PCI will be performed as per local practice for all lesions with RFR ≤0.89. For FFR, PCI will be performed as per local practice for all NCLs with FFR ≤0.80.', 'armGroupLabels': ['Physiology-guided Non-Culprit-Lesion (NCL) PCI']}, {'name': 'Angiography-guided NCL PCI', 'type': 'PROCEDURE', 'description': 'PCI will be performed as per local practice', 'armGroupLabels': ['Angiography-guided NCL PCI']}]}, 'contactsLocationsModule': {'locations': [{'zip': '90095', 'city': 'Los Angeles', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Rushi Parikh, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'UCLA', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '94143', 'city': 'San Francisco', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Krishan Soni, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of California, San Francisco', 'geoPoint': {'lat': 37.77493, 'lon': -122.41942}}, {'zip': '67226', 'city': 'Wichita', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Bassem Chehab, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Cardiovascular Research Institute of Kansas', 'geoPoint': {'lat': 37.69224, 'lon': -97.33754}}, {'zip': '21205', 'city': 'Baltimore', 'state': 'Maryland', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Peter Johnston, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The Johns Hopkins University School of Medicine', 'geoPoint': {'lat': 39.29038, 'lon': -76.61219}}, {'zip': '48109', 'city': 'Ann Arbor', 'state': 'Michigan', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Brett Wanamaker, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Michigan', 'geoPoint': {'lat': 42.27756, 'lon': -83.74088}}, {'zip': '55433', 'city': 'Coon Rapids', 'state': 'Minnesota', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Matthew Whitebeck, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Metropolitan Cardiology Consultants / Metropolitan Heart and Vascular Institute (MCC/MHVI)', 'geoPoint': {'lat': 45.11997, 'lon': -93.28773}}, {'zip': '07302', 'city': 'Jersey City', 'state': 'New Jersey', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Kimberly Skelding, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'RWJ Barnabas Health', 'geoPoint': {'lat': 40.72816, 'lon': -74.07764}}, {'zip': '13326', 'city': 'Cooperstown', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Dhananjai Menzies, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Bassett Medical Center', 'geoPoint': {'lat': 42.70048, 'lon': -74.92426}}, {'zip': '10010', 'city': 'New York', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Binita Shah, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'VA New York Harbor HealthCare System', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '10016', 'city': 'New York', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Sripal Bangalore, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'NYU Grossman School of Medicine', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '10467', 'city': 'The Bronx', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Mark Menegus, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Montefiore Medical Center', 'geoPoint': {'lat': 40.84985, 'lon': -73.86641}}, {'zip': '44195', 'city': 'Cleveland', 'state': 'Ohio', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jacqueline Tamis-Holland, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Cleveland Clinic', 'geoPoint': {'lat': 41.4995, 'lon': -81.69541}}, {'zip': '22903', 'city': 'Charlottesville', 'state': 'Virginia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Michael Ragosta, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Virginia Medical Center', 'geoPoint': {'lat': 38.02931, 'lon': -78.47668}}, {'city': 'Westmead', 'state': 'New South Wales', 'status': 'RECRUITING', 'country': 'Australia', 'contacts': [{'name': 'Sarah Zaman, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Westmead Hospital', 'geoPoint': {'lat': -33.80383, 'lon': 150.98768}}, {'city': 'Vienna', 'status': 'RECRUITING', 'country': 'Austria', 'contacts': [{'name': 'Andreas Schober, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Klinik Floridsdorf', 'geoPoint': {'lat': 48.20849, 'lon': 16.37208}}, {'zip': 'H4A 3J1', 'city': 'Montreal', 'state': 'Quebec', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Elie Akl, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'McGill University Health Centre (MUHC)', 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'city': 'Brampton', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Shy Amlani, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'William Osler Health System', 'geoPoint': {'lat': 43.68341, 'lon': -79.76633}}, {'city': 'Edmonton', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Robert Welsh, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Alberta Hospital, Mazankowski Heart', 'geoPoint': {'lat': 53.55014, 'lon': -113.46871}}, {'city': 'Hamilton', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Matthew Sibbald, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hamilton Health Sciences', 'geoPoint': {'lat': 43.25011, 'lon': -79.84963}}, {'city': 'Kingston', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Wael Abuzeid, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Kingston Health Sciences Centre', 'geoPoint': {'lat': 44.22976, 'lon': -76.48098}}, {'city': 'Kitchener', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Hahn Hoe Kim, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "St. Mary's General Hospital", 'geoPoint': {'lat': 43.42537, 'lon': -80.5112}}, {'city': 'London', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Shahar Lavi, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'London Health Sciences Centre', 'geoPoint': {'lat': 42.98339, 'lon': -81.23304}}, {'city': 'Montreal', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Samer Masour, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "Centre Hospitalier de l'Universite de Montreal", 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'city': 'Montreal', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Erick Schampaert, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hopital du Sacre-Coeur de Montreal', 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'city': 'Newmarket', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Warren Cantor, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Southlake Regional Health Centre', 'geoPoint': {'lat': 44.05011, 'lon': -79.46631}}, {'city': 'Nova Scotia', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Lawrence Title, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Nova Scotia Health'}, {'city': 'Ottawa', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Derek So, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Ottawa Heart Institute', 'geoPoint': {'lat': 45.41117, 'lon': -75.69812}}, {'city': 'Québec', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Tomas Cieza, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Institut Universitaire de Cardiologie et de Pneumologie de Québec', 'geoPoint': {'lat': 46.81228, 'lon': -71.21454}}, {'city': 'Regina', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Payam Dehghani, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Regina General Hospital', 'geoPoint': {'lat': 50.45008, 'lon': -104.6178}}, {'city': 'Saskatoon', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Jay Shavadia, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Royal University Hospital', 'geoPoint': {'lat': 52.13238, 'lon': -106.66892}}, {'city': 'St. Catharines', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Natalia Pinilla, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Niagara Health', 'geoPoint': {'lat': 43.17126, 'lon': -79.24267}}, {'city': "St. John's", 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Allison Hall, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Newfoundland and Labrador Health Services', 'geoPoint': {'lat': 47.56494, 'lon': -52.70931}}, {'city': 'Thunder Bay', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Alexandra Bastiany, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Thunder Bay Regional Health Sciences Centre', 'geoPoint': {'lat': 48.38202, 'lon': -89.25018}}, {'city': 'Toronto', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Akshay Bagai, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "St. Michael's Hospital (Unity Health Toronto)", 'geoPoint': {'lat': 43.70643, 'lon': -79.39864}}, {'city': 'Toronto', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Mina Madan, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Sunnybrook Health Sciences Centre', 'geoPoint': {'lat': 43.70643, 'lon': -79.39864}}, {'city': 'Trois-Rivières', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Vincent Spagnoli, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Ciusss McQ - Chaur', 'geoPoint': {'lat': 46.34515, 'lon': -72.5477}}, {'city': 'Vancouver', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Robert Boone, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "St Paul's Hospital", 'geoPoint': {'lat': 49.24966, 'lon': -123.11934}}, {'city': 'Vancouver', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'David Wood, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Vancouver General Hospital', 'geoPoint': {'lat': 49.24966, 'lon': -123.11934}}, {'city': 'Winnipeg', 'status': 'RECRUITING', 'country': 'Canada', 'contacts': [{'name': 'Kunal Minhas, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'St. Boniface Hospital', 'geoPoint': {'lat': 49.8844, 'lon': -97.14704}}, {'city': 'Brno', 'status': 'RECRUITING', 'country': 'Czechia', 'contacts': [{'name': 'Ota Hlinomaz, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "St. Anne's University Hospital", 'geoPoint': {'lat': 49.19522, 'lon': 16.60796}}, {'city': 'Aalborg', 'status': 'RECRUITING', 'country': 'Denmark', 'contacts': [{'name': 'Ashkan Eftekhari, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Aalborg University Hospital', 'geoPoint': {'lat': 57.048, 'lon': 9.9187}}, {'city': 'Aarhus', 'status': 'RECRUITING', 'country': 'Denmark', 'contacts': [{'name': 'Evald Hoj Christiansen, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Aarhus University Hospital', 'geoPoint': {'lat': 56.15674, 'lon': 10.21076}}, {'city': 'Copenhagen', 'status': 'RECRUITING', 'country': 'Denmark', 'contacts': [{'name': 'Thomas Engstrom, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Rigshospitalet - Copenhagen University Hospital', 'geoPoint': {'lat': 55.67594, 'lon': 12.56553}}, {'city': 'Helsinki', 'status': 'RECRUITING', 'country': 'Finland', 'contacts': [{'name': 'Pasi Karjalainen, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Helsinki University Hospital', 'geoPoint': {'lat': 60.16952, 'lon': 24.93545}}, {'city': 'Tampere', 'status': 'RECRUITING', 'country': 'Finland', 'contacts': [{'name': 'Olli Kajander, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'TAYS Sydankeskus Oy', 'geoPoint': {'lat': 61.49911, 'lon': 23.78712}}, {'city': 'Turku', 'status': 'RECRUITING', 'country': 'Finland', 'contacts': [{'name': 'Samuli Jaakkola, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Turku University Hospital', 'geoPoint': {'lat': 60.45148, 'lon': 22.26869}}, {'city': 'Cologne', 'status': 'RECRUITING', 'country': 'Germany', 'contacts': [{'name': 'Jan-Malte Sinning, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'St. Vinzenz-Hospital', 'geoPoint': {'lat': 50.93333, 'lon': 6.95}}, {'city': 'Dachau', 'status': 'RECRUITING', 'country': 'Germany', 'contacts': [{'name': 'Bernhard Witzenbichler, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Helios Amper-Klinikum', 'geoPoint': {'lat': 48.26, 'lon': 11.43402}}, {'city': 'Frankfurt', 'status': 'RECRUITING', 'country': 'Germany', 'contacts': [{'name': 'David Leistner, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Universitatsklinikum Frankfurt', 'geoPoint': {'lat': 49.68333, 'lon': 10.53333}}, {'city': 'Hamburg', 'status': 'RECRUITING', 'country': 'Germany', 'contacts': [{'name': 'Edith Lubos, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Marienkrankenhaus', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'city': 'Hamburg', 'status': 'RECRUITING', 'country': 'Germany', 'contacts': [{'name': 'Frank Hennersdorf, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Schoen Klink Hamburg', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'city': 'Hamburg', 'status': 'RECRUITING', 'country': 'Germany', 'contacts': [{'name': 'Fabian Brunner, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University Heart & Vascular Center Hamburg', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'city': 'Heide', 'status': 'RECRUITING', 'country': 'Germany', 'contacts': [{'name': 'Patrick Diemert, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'WKK Heide', 'geoPoint': {'lat': 54.19562, 'lon': 9.09742}}, {'city': 'Budapest', 'status': 'RECRUITING', 'country': 'Hungary', 'contacts': [{'name': 'Zsolt Piroth, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Gottsegen National Cardiovascular Center', 'geoPoint': {'lat': 47.49835, 'lon': 19.04045}}, {'city': 'Szeged', 'status': 'RECRUITING', 'country': 'Hungary', 'contacts': [{'name': 'Zoltan Ruzsa, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Szeged', 'geoPoint': {'lat': 46.253, 'lon': 20.14824}}, {'city': 'Ernākulam', 'state': 'Kerala', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Rony Matthew, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Lisie Hospital', 'geoPoint': {'lat': 9.96714, 'lon': 76.29036}}, {'city': 'Kollam', 'state': 'Kerala', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Prathap Kumar, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Meditrina Hospital', 'geoPoint': {'lat': 8.88113, 'lon': 76.58469}}, {'city': 'Kottayam', 'state': 'Kerala', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Deepak Davidson, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Caritas Hospital Trust', 'geoPoint': {'lat': 9.58692, 'lon': 76.52132}}, {'city': 'Indore', 'state': 'Madhya Pradesh', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Sarita Rao, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Apollo Rajshree Hospitals', 'geoPoint': {'lat': 22.71792, 'lon': 75.8333}}, {'city': 'Jaipur', 'state': 'Rajasthan', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Sanjeeb Roy, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Rukmani Birla Hospital', 'geoPoint': {'lat': 26.91962, 'lon': 75.78781}}, {'city': 'Chennai', 'state': 'Tamil Nadu', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Sengottuvelu Gunasekaran, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Apollo Hospital', 'geoPoint': {'lat': 13.08784, 'lon': 80.27847}}, {'city': 'Chennai', 'state': 'Tamil Nadu', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Ajit Mullasari, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The Madras Medical Mission', 'geoPoint': {'lat': 13.08784, 'lon': 80.27847}}, {'city': 'Madurai', 'state': 'Tamil Nadu', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Selvamani Sethuraman, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Meenakshi Mission Hospital and Research Center', 'geoPoint': {'lat': 9.919, 'lon': 78.11953}}, {'city': 'Hyderabad', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Sharath Reddy Annam, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Medicover Hospitals', 'geoPoint': {'lat': 17.38405, 'lon': 78.45636}}, {'city': 'Secunderabad', 'status': 'RECRUITING', 'country': 'India', 'contacts': [{'name': 'Ajay Jagannath Swamy, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Krishna Institute of Medical Sciences', 'geoPoint': {'lat': 17.50427, 'lon': 78.54263}}, {'city': 'Arezzo', 'status': 'RECRUITING', 'country': 'Italy', 'contacts': [{'name': 'Kenneth Ducci, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Azienda USL Toscana Sud Est', 'geoPoint': {'lat': 43.46276, 'lon': 11.88068}}, {'city': 'Bologna', 'status': 'RECRUITING', 'country': 'Italy', 'contacts': [{'name': 'Gianni Casella, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'UOC Cardiologia - Ospedale Maggiore', 'geoPoint': {'lat': 44.49381, 'lon': 11.33875}}, {'city': 'Ferrara', 'status': 'RECRUITING', 'country': 'Italy', 'contacts': [{'name': 'Gianluca Campo, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Azienda Ospedaliero - Universitaria di Ferrara', 'geoPoint': {'lat': 44.83804, 'lon': 11.62057}}, {'city': 'Grosseto', 'status': 'RECRUITING', 'country': 'Italy', 'contacts': [{'name': 'Andrea Picchi, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Misericordia Hospital', 'geoPoint': {'lat': 42.76296, 'lon': 11.10941}}, {'city': 'Reggio Emilia', 'status': 'RECRUITING', 'country': 'Italy', 'contacts': [{'name': 'Vincenzo Guiducci, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Azienda USL-IRCCS di Reggio Emilia, Reggio', 'geoPoint': {'lat': 44.69825, 'lon': 10.63125}}, {'city': 'Rome', 'status': 'RECRUITING', 'country': 'Italy', 'contacts': [{'name': 'Emanuele Barbato, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Sant Andrea Hospital - Sapienza University', 'geoPoint': {'lat': 41.89193, 'lon': 12.51133}}, {'city': 'Kristiansand', 'state': 'Arendal', 'status': 'RECRUITING', 'country': 'Norway', 'contacts': [{'name': 'Slobodan Calic, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Sorlandet Hospital Arendal', 'geoPoint': {'lat': 58.14671, 'lon': 7.9956}}, {'city': 'Oslo', 'status': 'RECRUITING', 'country': 'Norway', 'contacts': [{'name': 'Trygve Sundby Hall, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Oslo University Hospital Ulleval', 'geoPoint': {'lat': 59.91273, 'lon': 10.74609}}, {'city': 'Stavanger', 'status': 'RECRUITING', 'country': 'Norway', 'contacts': [{'name': 'Alf Inge Larsen, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Stavanger University Hospital', 'geoPoint': {'lat': 58.97005, 'lon': 5.73332}}, {'city': 'Tromsø', 'status': 'RECRUITING', 'country': 'Norway', 'contacts': [{'name': 'Andreas Kristensen, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University Hospital Tromso', 'geoPoint': {'lat': 69.6489, 'lon': 18.95508}}, {'city': 'Legnica', 'state': 'Lower Silesian Voivodeship', 'status': 'RECRUITING', 'country': 'Poland', 'contacts': [{'name': 'Piotr Rola, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Provincial Specialized Hospital', 'geoPoint': {'lat': 51.21006, 'lon': 16.1619}}, {'city': 'Lubin', 'state': 'Lower Silesian Voivodeship', 'status': 'RECRUITING', 'country': 'Poland', 'contacts': [{'name': 'Adrian Wlodarczak, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Miedziowym Centrum Zdrowia S.A. w Lubinie', 'geoPoint': {'lat': 51.40089, 'lon': 16.20149}}, {'city': 'Warsaw', 'state': 'Masovian Voivodeship', 'status': 'RECRUITING', 'country': 'Poland', 'contacts': [{'name': 'Lukasz Koltowski, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Medical University of Warsaw', 'geoPoint': {'lat': 52.22977, 'lon': 21.01178}}, {'city': 'Belgrade', 'status': 'RECRUITING', 'country': 'Serbia', 'contacts': [{'name': 'Dragan Topic, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Institute for Cardiovascular Diseases Dedinje', 'geoPoint': {'lat': 44.80401, 'lon': 20.46513}}, {'city': 'Belgrade', 'status': 'RECRUITING', 'country': 'Serbia', 'contacts': [{'name': 'Goran Stankovic, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University Clinical Center of Serbia', 'geoPoint': {'lat': 44.80401, 'lon': 20.46513}}, {'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'contacts': [{'name': 'Nieves Gonzalo, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hospital Clinico San Carlos', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'contacts': [{'name': 'Ana Pardo, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hospital Ramon y Cajal', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'contacts': [{'name': 'Fernando Alfonso Manterola, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hospital Universitario de La Princesa', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'contacts': [{'name': 'Raul Moreno Gomez, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hospital Universitario La Paz', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'city': 'Seville', 'status': 'RECRUITING', 'country': 'Spain', 'contacts': [{'name': 'Jose Francisco Diaz Fernandez, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hospital Virgen del Rocio', 'geoPoint': {'lat': 37.38283, 'lon': -5.97317}}, {'city': 'Valencia', 'status': 'RECRUITING', 'country': 'Spain', 'contacts': [{'name': 'Jose Luis Diez, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hospital Universitari i Politecnic La Fe', 'geoPoint': {'lat': 39.47391, 'lon': -0.37966}}, {'city': 'Valladolid', 'status': 'RECRUITING', 'country': 'Spain', 'contacts': [{'name': 'Ignacio J Amat Santos, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hospital Clinico Universitario de Valladolid', 'geoPoint': {'lat': 41.65541, 'lon': -4.72353}}, {'city': 'Huddinge', 'status': 'RECRUITING', 'country': 'Sweden', 'contacts': [{'name': 'Juliane Jurga, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Karolinska University Hospital', 'geoPoint': {'lat': 59.23705, 'lon': 17.98192}}, {'city': 'Jönköping', 'status': 'RECRUITING', 'country': 'Sweden', 'contacts': [{'name': 'Neshro Barmano, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Lanssjukhuset RYHOV', 'geoPoint': {'lat': 57.78145, 'lon': 14.15618}}, {'city': 'Karlstad', 'status': 'RECRUITING', 'country': 'Sweden', 'contacts': [{'name': 'Payam Khalili, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Karlstad Central Hospital', 'geoPoint': {'lat': 59.3793, 'lon': 13.50357}}, {'city': 'Lund', 'status': 'RECRUITING', 'country': 'Sweden', 'contacts': [{'name': 'David Erlinge, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Skane University Hospital', 'geoPoint': {'lat': 55.70584, 'lon': 13.19321}}, {'city': 'Stockholm', 'status': 'RECRUITING', 'country': 'Sweden', 'contacts': [{'name': 'Felix Bohm, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Danderyd Hospital', 'geoPoint': {'lat': 59.32938, 'lon': 18.06871}}, {'city': 'Umeå', 'status': 'RECRUITING', 'country': 'Sweden', 'contacts': [{'name': 'Jonas Andersson, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Umeå University Hospital', 'geoPoint': {'lat': 63.82842, 'lon': 20.25972}}, {'city': 'Uppsala', 'status': 'RECRUITING', 'country': 'Sweden', 'contacts': [{'name': 'Kasper Andersen, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Uppsala University Hospital', 'geoPoint': {'lat': 59.85882, 'lon': 17.63889}}, {'city': 'Ashford', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Rajiv Rampat, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'East Kent Hospitals University NHS Foundation Trust', 'geoPoint': {'lat': 51.14648, 'lon': 0.87376}}, {'city': 'Blackpool', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Gavin Galasko, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Blackpool Teaching Hospitals', 'geoPoint': {'lat': 53.81667, 'lon': -3.05}}, {'city': 'Dundee', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'John Irving, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Ninewells Hospital', 'geoPoint': {'lat': 56.46913, 'lon': -2.97489}}, {'city': 'Harefield', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Mohammed Akhtar, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Harefield Hospital', 'geoPoint': {'lat': 51.60333, 'lon': -0.48546}}, {'city': 'Kettering', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Simon Hetherington, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Kettering General Hospital', 'geoPoint': {'lat': 52.39836, 'lon': -0.72571}}, {'city': 'Leicester', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Andrew Ladwiniec, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University Hospitals of Leicester', 'geoPoint': {'lat': 52.6386, 'lon': -1.13169}}, {'city': 'Liverpool', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Joel Giblett, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Liverpool Heart and Chest Hospital', 'geoPoint': {'lat': 53.41058, 'lon': -2.97794}}, {'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Dan Jones, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Barts Health NHS Trust', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Sukhjinder Nijjer, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Imperial College Healthcare NHS Trust', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Sundeep Kalra, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Royal Free London NHS Foundation Trust', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'city': 'Manchester', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Jaydeep Sarma, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Manchester University NHS Foundation Trust', 'geoPoint': {'lat': 53.48095, 'lon': -2.23743}}, {'city': 'Middlesbrough', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'David Austin, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The James Cook University Hospital', 'geoPoint': {'lat': 54.57623, 'lon': -1.23483}}, {'city': 'Newcastle upon Tyne', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Mohammad Alkhalil, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Freeman Hospital', 'geoPoint': {'lat': 54.97328, 'lon': -1.61396}}, {'city': 'Reading', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Neil Ruparelia, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Royal Berkshire Foundation NHS Trust', 'geoPoint': {'lat': 51.45625, 'lon': -0.97113}}, {'city': 'Sheffield', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'James Richardson, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Sheffield Teaching Hospitals', 'geoPoint': {'lat': 53.38297, 'lon': -1.4659}}, {'city': 'Stevenage', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Manivannan Srinivasan, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'East and North Hertfordshire NHS Trust', 'geoPoint': {'lat': 51.90224, 'lon': -0.20256}}, {'city': 'Truro', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Sen Devadathan, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Royal Cornwall Hospitals NHS Trust', 'geoPoint': {'lat': 50.26526, 'lon': -5.05436}}, {'city': 'Wolverhampton', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Benjamin Wrigley, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The Royal Wolverhampton NHS Trust', 'geoPoint': {'lat': 52.58547, 'lon': -2.12296}}, {'city': 'Worcester', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Helen Routledge, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Worcestershire Acute Hospitals NHS Trust', 'geoPoint': {'lat': 52.18935, 'lon': -2.22001}}], 'centralContacts': [{'name': 'COMPLETE-2 Project Office', 'role': 'CONTACT', 'email': 'complete-2@phri.ca', 'phone': '(905) 521-2100'}], 'overallOfficials': [{'name': 'Shamir Mehta, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Population Health Research Institute'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Population Health Research Institute', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}