Ignite Creation Date:
2025-12-24 @ 1:55 PM
Ignite Modification Date:
2025-12-28 @ 11:16 PM
Study NCT ID:
NCT03449095
Status:
COMPLETED
Last Update Posted:
2024-07-31
First Post:
2017-11-23
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Understanding Alcohol Reward in Social Context
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000428', 'term': 'Alcohol Drinking'}, {'id': 'D000437', 'term': 'Alcoholism'}, {'id': 'D000435', 'term': 'Alcoholic Intoxication'}, {'id': 'D063425', 'term': 'Binge Drinking'}], 'ancestors': [{'id': 'D004327', 'term': 'Drinking Behavior'}, {'id': 'D001519', 'term': 'Behavior'}, {'id': 'D019973', 'term': 'Alcohol-Related Disorders'}, {'id': 'D019966', 'term': 'Substance-Related Disorders'}, {'id': 'D064419', 'term': 'Chemically-Induced Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D000431', 'term': 'Ethanol'}], 'ancestors': [{'id': 'D000438', 'term': 'Alcohols'}, {'id': 'D009930', 'term': 'Organic Chemicals'}]}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'cfairbai@illinois.edu', 'phone': '215-300-5850', 'title': 'Dr. Catharine Fairbairn', 'organization': 'University of Illinois at Urbana-Champaign'}, 'certainAgreement': {'piSponsorEmployee': False, 'restrictiveAgreement': False}}, 'adverseEventsModule': {'timeFrame': '6-9 hours (length of the laboratory session)', 'description': 'The intervention of the study is laboratory alcohol administration.', 'eventGroups': [{'id': 'EG000', 'title': 'Alcohol Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the number of individual participants (both initial contacts and their friends) who received a moderate dose of alcohol (Target BAC .08%).', 'otherNumAtRisk': 320, 'deathsNumAtRisk': 320, 'otherNumAffected': 0, 'seriousNumAtRisk': 320, 'deathsNumAffected': 0, 'seriousNumAffected': 0}, {'id': 'EG001', 'title': 'Control Beverage Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the number of individual participants (both initial contacts and their friends) who received a non-alcoholic beverage.', 'otherNumAtRisk': 320, 'deathsNumAtRisk': 320, 'otherNumAffected': 0, 'seriousNumAtRisk': 320, 'deathsNumAffected': 0, 'seriousNumAffected': 0}], 'frequencyThreshold': '1'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Self-Reported Emotion', 'denoms': [{'units': 'Participants', 'counts': [{'value': '320', 'groupId': 'OG000'}, {'value': '320', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Alcohol Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the data from individual participants (both initial contacts and their friends) who received a moderate dose of alcohol (Target BAC .08%).'}, {'id': 'OG001', 'title': 'Control Beverage Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the data from individual participants (both initial contacts and their friends) who received a non-alcoholic beverage.'}], 'classes': [{'title': 'Positive Emotion', 'categories': [{'measurements': [{'value': '3.49', 'spread': '1.085', 'groupId': 'OG000'}, {'value': '2.98', 'spread': '1.101', 'groupId': 'OG001'}]}]}, {'title': 'Negative Emotion', 'categories': [{'measurements': [{'value': '0.32', 'spread': '0.447', 'groupId': 'OG000'}, {'value': '0.673', 'spread': '0.750', 'groupId': 'OG001'}]}]}], 'analyses': [{'pValue': '<0.001', 'groupIds': ['OG000', 'OG001'], 'pValueComment': 'The reported p-value was calculated, and is not attempting to indicate the threshold for statistical significance.', 'statisticalMethod': 'ANOVA', 'nonInferiorityType': 'SUPERIORITY'}], 'paramType': 'MEAN', 'timeFrame': 'during the laboratory session, up to 9 hours', 'description': 'Positive and negative emotion will be assessed during the laboratory beverage-administration session via self-report on the "8-item Mood Measure." This measure yields two subscales (positive emotion; negative emotion) each ranges from 1 to 6. For positive mood, higher value represents increased alcohol reward. For negative mood, lower value represents increased alcohol reward.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}, {'type': 'PRIMARY', 'title': 'Self-Reported Social Reinforcement', 'denoms': [{'units': 'Participants', 'counts': [{'value': '320', 'groupId': 'OG000'}, {'value': '320', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Alcohol Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the data from individual participants (both initial contacts and their friends) who received a moderate dose of alcohol (Target BAC .08%).'}, {'id': 'OG001', 'title': 'Control Beverage Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the data from individual participants (both initial contacts and their friends) who received a non-alcoholic beverage.'}], 'classes': [{'categories': [{'measurements': [{'value': '7.471', 'spread': '1.129', 'groupId': 'OG000'}, {'value': '7.180', 'spread': '1.155', 'groupId': 'OG001'}]}]}], 'analyses': [{'pValue': '.001', 'groupIds': ['OG000', 'OG001'], 'pValueComment': 'The reported p-value was calculated, and is not attempting to indicate the threshold for statistical significance.', 'statisticalMethod': 'ANCOVA', 'nonInferiorityType': 'SUPERIORITY'}], 'paramType': 'MEAN', 'timeFrame': 'during the laboratory session, up to 9 hours', 'description': 'Social reinforcement will be assessed using an index of perceived social closeness as well as a modified version of the Perceived Group Reinforcement Scale. The score of the scale ranges from 1 to 9. Higher score indicates increased alcohol reward.', 'unitOfMeasure': 'score on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED'}, {'type': 'SECONDARY', 'title': 'Social Bonding', 'timeFrame': '1 day (laboratory session)', 'description': 'Social bonding will be assessed during the laboratory beverage-administration session. This will be assessed by examining the synchronization among group members of facial expressions of emotion.', 'reportingStatus': 'NOT_POSTED', 'denomUnitsSelected': 'Participants'}, {'type': 'SECONDARY', 'title': 'Self-Reported Emotion', 'timeFrame': '2-3 week ambulatory assessment period', 'description': 'Positive and negative emotion will be assessed during the ambulatory assessment period via self-report on the "8-item Mood Measure."', 'reportingStatus': 'NOT_POSTED', 'denomUnitsSelected': 'Participants'}, {'type': 'SECONDARY', 'title': 'Interpersonal Distance', 'timeFrame': '1 day (laboratory session)', 'description': 'Physical proximity to other participants during the experiment', 'reportingStatus': 'NOT_POSTED', 'denomUnitsSelected': 'Participants'}, {'type': 'SECONDARY', 'title': 'Neuro-cognitive Social Engagement', 'timeFrame': '1 day (laboratory session)', 'description': 'Electroencephalogram (EEG) hyperscanning methods will be employed to assess task engagement and social attention, including through the examination of event-related potentials (ERPs) during social tasks.', 'reportingStatus': 'NOT_POSTED', 'denomUnitsSelected': 'Participants'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Alcohol Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the total number of individual participants (both initial contacts and their friends) who received a moderate dose of alcohol (Target BAC .08%).'}, {'id': 'FG001', 'title': 'Control Beverage Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the total number of individual participants (both initial contacts and their friends) who received a non-alcoholic beverage.'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '320'}, {'groupId': 'FG001', 'numSubjects': '320'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '320'}, {'groupId': 'FG001', 'numSubjects': '320'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '0'}, {'groupId': 'FG001', 'numSubjects': '0'}]}]}]}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '320', 'groupId': 'BG000'}, {'value': '320', 'groupId': 'BG001'}, {'value': '640', 'groupId': 'BG002'}]}], 'groups': [{'id': 'BG000', 'title': 'Alcohol Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the data from individual participants (both initial contacts and their friends) who received a moderate dose of alcohol (Target BAC .08%).'}, {'id': 'BG001', 'title': 'Control Beverage Administration', 'description': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the data from individual participants (both initial contacts and their friends) who received a non-alcoholic beverage.'}, {'id': 'BG002', 'title': 'Total', 'description': 'Total of all reporting groups'}], 'measures': [{'title': 'Age, Continuous', 'classes': [{'categories': [{'measurements': [{'value': '22.63', 'spread': '1.923', 'groupId': 'BG000'}, {'value': '22.74', 'spread': '2.101', 'groupId': 'BG001'}, {'value': '22.69', 'spread': '2.013', 'groupId': 'BG002'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'years', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '160', 'groupId': 'BG000'}, {'value': '160', 'groupId': 'BG001'}, {'value': '320', 'groupId': 'BG002'}]}, {'title': 'Male', 'measurements': [{'value': '160', 'groupId': 'BG000'}, {'value': '160', 'groupId': 'BG001'}, {'value': '320', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Ethnicity (NIH/OMB)', 'classes': [{'categories': [{'title': 'Hispanic or Latino', 'measurements': [{'value': '66', 'groupId': 'BG000'}, {'value': '68', 'groupId': 'BG001'}, {'value': '134', 'groupId': 'BG002'}]}, {'title': 'Not Hispanic or Latino', 'measurements': [{'value': '254', 'groupId': 'BG000'}, {'value': '252', 'groupId': 'BG001'}, {'value': '506', 'groupId': 'BG002'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': '0', 'groupId': 'BG000'}, {'value': '0', 'groupId': 'BG001'}, {'value': '0', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Race (NIH/OMB)', 'classes': [{'categories': [{'title': 'American Indian or Alaska Native', 'measurements': [{'value': '2', 'groupId': 'BG000'}, {'value': '1', 'groupId': 'BG001'}, {'value': '3', 'groupId': 'BG002'}]}, {'title': 'Asian', 'measurements': [{'value': '110', 'groupId': 'BG000'}, {'value': '129', 'groupId': 'BG001'}, {'value': '239', 'groupId': 'BG002'}]}, {'title': 'Native Hawaiian or Other Pacific Islander', 'measurements': [{'value': '0', 'groupId': 'BG000'}, {'value': '0', 'groupId': 'BG001'}, {'value': '0', 'groupId': 'BG002'}]}, {'title': 'Black or African American', 'measurements': [{'value': '13', 'groupId': 'BG000'}, {'value': '11', 'groupId': 'BG001'}, {'value': '24', 'groupId': 'BG002'}]}, {'title': 'White', 'measurements': [{'value': '180', 'groupId': 'BG000'}, {'value': '164', 'groupId': 'BG001'}, {'value': '344', 'groupId': 'BG002'}]}, {'title': 'More than one race', 'measurements': [{'value': '15', 'groupId': 'BG000'}, {'value': '15', 'groupId': 'BG001'}, {'value': '30', 'groupId': 'BG002'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': '0', 'groupId': 'BG000'}, {'value': '0', 'groupId': 'BG001'}, {'value': '0', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Region of Enrollment', 'classes': [{'title': 'United States', 'categories': [{'measurements': [{'value': '320', 'groupId': 'BG000'}, {'value': '320', 'groupId': 'BG001'}, {'value': '640', 'groupId': 'BG002'}]}]}], 'paramType': 'NUMBER', 'unitOfMeasure': 'participants'}, {'title': 'Education level', 'classes': [{'categories': [{'measurements': [{'value': '16.08', 'spread': '1.716', 'groupId': 'BG000'}, {'value': '16.09', 'spread': '1.741', 'groupId': 'BG001'}, {'value': '16.08', 'spread': '1.727', 'groupId': 'BG002'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'Years of Education', 'dispersionType': 'STANDARD_DEVIATION'}], 'populationDescription': 'Primary participants in the current study consisted of both eligible individuals who first contacted the lab and their eligible friends. Here we report the total number of individual participants (both initial contacts and their friends) enrolled in the study.'}}, 'documentSection': {'largeDocumentModule': {'largeDocs': [{'date': '2024-04-23', 'size': 116103, 'label': 'Study Protocol and Statistical Analysis Plan', 'hasIcf': False, 'hasSap': True, 'filename': 'Prot_SAP_001.pdf', 'typeAbbrev': 'Prot_SAP', 'uploadDate': '2024-04-24T14:08', 'hasProtocol': True}, {'date': '2022-02-22', 'size': 885316, 'label': 'Informed Consent Form', 'hasIcf': True, 'hasSap': False, 'filename': 'ICF_000.pdf', 'typeAbbrev': 'ICF', 'uploadDate': '2022-06-21T18:18', 'hasProtocol': False}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'BASIC_SCIENCE', 'interventionModel': 'FACTORIAL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 640}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2017-11-04', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2024-07', 'completionDateStruct': {'date': '2023-07-05', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2024-07-03', 'studyFirstSubmitDate': '2017-11-23', 'resultsFirstSubmitDate': '2024-04-27', 'studyFirstSubmitQcDate': '2018-02-27', 'lastUpdatePostDateStruct': {'date': '2024-07-31', 'type': 'ACTUAL'}, 'resultsFirstSubmitQcDate': '2024-07-03', 'studyFirstPostDateStruct': {'date': '2018-02-28', 'type': 'ACTUAL'}, 'resultsFirstPostDateStruct': {'date': '2024-07-31', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2023-07-05', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Self-Reported Emotion', 'timeFrame': 'during the laboratory session, up to 9 hours', 'description': 'Positive and negative emotion will be assessed during the laboratory beverage-administration session via self-report on the "8-item Mood Measure." This measure yields two subscales (positive emotion; negative emotion) each ranges from 1 to 6. For positive mood, higher value represents increased alcohol reward. For negative mood, lower value represents increased alcohol reward.'}, {'measure': 'Self-Reported Social Reinforcement', 'timeFrame': 'during the laboratory session, up to 9 hours', 'description': 'Social reinforcement will be assessed using an index of perceived social closeness as well as a modified version of the Perceived Group Reinforcement Scale. The score of the scale ranges from 1 to 9. Higher score indicates increased alcohol reward.'}], 'secondaryOutcomes': [{'measure': 'Social Bonding', 'timeFrame': '1 day (laboratory session)', 'description': 'Social bonding will be assessed during the laboratory beverage-administration session. This will be assessed by examining the synchronization among group members of facial expressions of emotion.'}, {'measure': 'Self-Reported Emotion', 'timeFrame': '2-3 week ambulatory assessment period', 'description': 'Positive and negative emotion will be assessed during the ambulatory assessment period via self-report on the "8-item Mood Measure."'}, {'measure': 'Interpersonal Distance', 'timeFrame': '1 day (laboratory session)', 'description': 'Physical proximity to other participants during the experiment'}, {'measure': 'Neuro-cognitive Social Engagement', 'timeFrame': '1 day (laboratory session)', 'description': 'Electroencephalogram (EEG) hyperscanning methods will be employed to assess task engagement and social attention, including through the examination of event-related potentials (ERPs) during social tasks.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Alcohol Drinking', 'Alcohol Use Disorder', 'Alcohol Intoxication', 'Alcohol; Harmful Use', 'Alcoholism', 'Binge Drinking']}, 'referencesModule': {'references': [{'pmid': '2221564', 'type': 'BACKGROUND', 'citation': 'Steele CM, Josephs RA. Alcohol myopia. Its prized and dangerous effects. Am Psychol. 1990 Aug;45(8):921-33. doi: 10.1037//0003-066x.45.8.921.'}, {'pmid': '28287750', 'type': 'BACKGROUND', 'citation': "Fairbairn CE. Drinking among strangers: A meta-analysis examining familiarity as a moderator of alcohol's rewarding effects. Psychol Addict Behav. 2017 May;31(3):255-264. doi: 10.1037/adb0000264. Epub 2017 Mar 13."}, {'pmid': '25180806', 'type': 'BACKGROUND', 'citation': 'Fairbairn CE, Sayette MA. A social-attributional analysis of alcohol response. Psychol Bull. 2014 Sep;140(5):1361-82. doi: 10.1037/a0037563.'}, {'pmid': '22760882', 'type': 'BACKGROUND', 'citation': 'Sayette MA, Creswell KG, Dimoff JD, Fairbairn CE, Cohn JF, Heckman BW, Kirchner TR, Levine JM, Moreland RL. Alcohol and group formation: a multimodal investigation of the effects of alcohol on emotion and social bonding. Psychol Sci. 2012 Aug 1;23(8):869-78. doi: 10.1177/0956797611435134. Epub 2012 Jul 3.'}, {'pmid': '24016015', 'type': 'BACKGROUND', 'citation': 'Fairbairn CE, Sayette MA. The effect of alcohol on emotional inertia: a test of alcohol myopia. J Abnorm Psychol. 2013 Aug;122(3):770-81. doi: 10.1037/a0032980.'}]}, 'descriptionModule': {'briefSummary': 'In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.', 'detailedDescription': "Objective: Although the vast majority of alcohol consumption outside the laboratory occurs in social context, experimental studies of alcohol's emotionally reinforcing effects have overwhelmingly examined individuals drinking in isolation. The current study examines motivationally salient elements of everyday social drinking contexts as moderators of alcohol-related reinforcement. More specifically, the present study examine whether alcohol is more reinforcing within the context of unfamiliar vs. familiar social interaction and, further, whether alcohol is more reinforcing within the context of low vs. high quality social relationships. The current study furthermore examine whether individuals with characteristics that put them at risk for developing an alcohol use disorder (e.g., male gender, impulsive/extraverted personality profile, heavy patterns of consumption, family history of AUD, ...) exhibit heightened emotional reinforcement from alcohol within these social drinking contexts.\n\nThe current project represents a test of competing theories of alcohol reinforcement. Alcohol myopia theory-which has heretofore represented the most prominent theory of alcohol's effects-predicts that alcohol's ability to relieve stress depends on the nature (positive or negative) of stimuli in the drinker's immediate environment. Alcohol myopia theory might thus predict that alcohol's rewarding effects will be larger within familiar interactions and within secure relationships. In contrast, the social attributional theory of alcohol reinforcement predicts that alcohol-related reinforcement will be most pronounced within the context of unfamiliar social interactions.\n\nIn addition to providing an opportunity to test contextual and individual-level moderators of alcohol reinforcement, the current study represents an opportunity to directly test the replicability of research indicating a pronounced reinforcing effect of alcohol specifically within interactions among unfamiliar individuals (Sayette et al., 2012; Fairbairn et al., 2013).\n\nStudy Population: Participants will consist of 640 male and female drinkers, aged 21-30, with no reported history of severe alcohol use disorder. Participants will be sampled such that at least 360 of these participants will classify as heavy drinkers.\n\nDesign: In the laboratory arm of the study, individuals will be randomly assigned to consume either a moderate dose of alcohol or a control beverage in the company of either familiar or unfamiliar individuals. Of these individuals, a subset will participate in additional tasks post beverage-consumption including a hyperscanning EEG task, while an additional subset will also participate in an ambulatory assessment period over the course of several weeks to examine the interaction of alcohol and social contextual factors in daily life. In the ambulatory study arm, participants will wear transdermal sensors to assess BAC and will further provide information about their mood and their social contexts in response to random prompts.\n\nOutcome Measures: Primary outcome measures include self-reports of positive and negative mood and perceived social reinforcement. The investigators will also examine facial expressions using the Facial Action Coding System, a comprehensive, anatomically-based system for categorizing facial muscle movement. One aim of the current study is to examine whether differential reinforcement from alcohol in unfamiliar social contexts emerges only with respect to self-reports, or is also observable within facial behaviors. EEG/ERP measures will also be examined for a subset of participants engaged in a hyperscanning task."}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '30 Years', 'minimumAge': '21 Years', 'genderBased': True, 'genderDescription': 'May be either male or female, but must be same as gender assigned at birth.', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Between the ages of 21 and 30\n* Currently drinks alcohol\n* Able to provide at least 2 same-gender friend referrals\n\nExclusion Criteria:\n\n* Female participant is pregnant or trying to become pregnant\n* Endorsed medical disorder caused by, or made worse by, alcohol\n* History of severe alcohol problems\n* Use of drugs known to interact with alcohol'}, 'identificationModule': {'nctId': 'NCT03449095', 'briefTitle': 'Understanding Alcohol Reward in Social Context', 'organization': {'class': 'OTHER', 'fullName': 'University of Illinois at Urbana-Champaign'}, 'officialTitle': 'Examining the Impact of Stress on the Emotionally Reinforcing Properties of Alcohol in Heavy Social Drinkers: A Multimodal Investigation Integrating Laboratory and Ambulatory Methods', 'orgStudyIdInfo': {'id': 'R01AA025969', 'link': 'https://reporter.nih.gov/quickSearch/R01AA025969', 'type': 'NIH'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Alcohol Administration', 'description': 'A moderate dose of alcohol (Target BAC .08%)', 'interventionNames': ['Drug: Alcohol']}, {'type': 'NO_INTERVENTION', 'label': 'Control Beverage Administration', 'description': 'Participants consume a non-alcoholic beverage'}], 'interventions': [{'name': 'Alcohol', 'type': 'DRUG', 'description': 'Alcohol Target BAC .08%', 'armGroupLabels': ['Alcohol Administration']}]}, 'contactsLocationsModule': {'locations': [{'zip': '61820', 'city': 'Champaign', 'state': 'Illinois', 'country': 'United States', 'facility': 'University of Illinois at Urbana-Champaign', 'geoPoint': {'lat': 40.11642, 'lon': -88.24338}}], 'overallOfficials': [{'name': 'Catharine E Fairbairn, Ph.D.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of Illinois at Urbana-Champaign'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Illinois at Urbana-Champaign', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Associate Professor', 'investigatorFullName': 'Catharine Fairbairn', 'investigatorAffiliation': 'University of Illinois at Urbana-Champaign'}}}}