Ignite Creation Date:
2025-12-24 @ 11:58 PM
Ignite Modification Date:
2025-12-25 @ 9:56 PM
Study NCT ID:
NCT01296958
Status:
COMPLETED
Last Update Posted:
2014-10-24
First Post:
2011-02-15
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Targeted Screening for Taenia Solium Tapeworms
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D013622', 'term': 'Taeniasis'}, {'id': 'D003551', 'term': 'Cysticercosis'}, {'id': 'D020019', 'term': 'Neurocysticercosis'}], 'ancestors': [{'id': 'D002590', 'term': 'Cestode Infections'}, {'id': 'D006373', 'term': 'Helminthiasis'}, {'id': 'D010272', 'term': 'Parasitic Diseases'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D020809', 'term': 'Central Nervous System Helminthiasis'}, {'id': 'D020807', 'term': 'Central Nervous System Parasitic Infections'}, {'id': 'D002494', 'term': 'Central Nervous System Infections'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D009534', 'term': 'Niclosamide'}], 'ancestors': [{'id': 'D012458', 'term': 'Salicylanilides'}, {'id': 'D000813', 'term': 'Anilides'}, {'id': 'D000577', 'term': 'Amides'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D012457', 'term': 'Salicylamides'}, {'id': 'D000814', 'term': 'Aniline Compounds'}, {'id': 'D000588', 'term': 'Amines'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NON_RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'SCREENING', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 1811}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2011-05'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2014-10', 'completionDateStruct': {'date': '2013-01', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2014-10-22', 'studyFirstSubmitDate': '2011-02-15', 'studyFirstSubmitQcDate': '2011-02-15', 'lastUpdatePostDateStruct': {'date': '2014-10-24', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2011-02-16', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2013-01', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Porcine seroprevalence', 'timeFrame': 'Every 4 months'}], 'secondaryOutcomes': [{'measure': 'Intestinal tapeworm prevalence', 'timeFrame': '16 months'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Taenia solium', 'cysticercosis', 'neurocysticercosis'], 'conditions': ['Taenia Solium Taeniasis']}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to determine whether screening and treatment of tapeworm carriers can decrease community transmission of Taenia solium parasitic infection.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* All community members are eligible\n\nExclusion Criteria:\n\n* Inability to provide informed consent'}, 'identificationModule': {'nctId': 'NCT01296958', 'briefTitle': 'Targeted Screening for Taenia Solium Tapeworms', 'organization': {'class': 'OTHER', 'fullName': 'Oregon Health and Science University'}, 'officialTitle': 'Targeted Screening for Taenia Solium Tapeworms', 'orgStudyIdInfo': {'id': '1R21NS069275-01', 'link': 'https://reporter.nih.gov/quickSearch/1R21NS069275-01', 'type': 'NIH'}, 'secondaryIdInfos': [{'id': '1R21NS069275-01', 'link': 'https://reporter.nih.gov/quickSearch/1R21NS069275-01', 'type': 'NIH'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Targeted screening', 'description': 'Screening for intestinal tapeworm carrier followed by treatment with niclosamide as indicated.', 'interventionNames': ['Drug: Niclosamide']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Education', 'description': 'Community education about Taenia solium prevention.', 'interventionNames': ['Behavioral: Community education campaign']}], 'interventions': [{'name': 'Niclosamide', 'type': 'DRUG', 'description': 'Single oral dose of niclosamide determined by weight (dose: 11 to 34kg receive 1 gram, 35 to 50kg receive 1.5 grams, over 50kg receive 2 grams)', 'armGroupLabels': ['Targeted screening']}, {'name': 'Community education campaign', 'type': 'BEHAVIORAL', 'description': 'Education about prevention of Taenia solium infection provided in a single short (20 minute) interaction with the participant. Education was verbal with visual aids.', 'armGroupLabels': ['Education']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Lima', 'country': 'Peru', 'facility': 'San Marcos University', 'geoPoint': {'lat': -12.04318, 'lon': -77.02824}}], 'overallOfficials': [{'name': 'Seth E ONeal, MD MPH', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Oregon Health and Science University'}, {'name': 'Armando Gonzalez, DVM PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'San Marcos University School of Veterinary Medicine'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Oregon Health and Science University', 'class': 'OTHER'}, 'collaborators': [{'name': 'National University of San Marcos, Peru', 'class': 'OTHER'}, {'name': 'National Institute of Neurological Disorders and Stroke (NINDS)', 'class': 'NIH'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Assistant professor', 'investigatorFullName': "Seth E O'Neal, MD MPH", 'investigatorAffiliation': 'Oregon Health and Science University'}}}}