Ignite Creation Date:
2025-12-24 @ 11:57 PM
Ignite Modification Date:
2026-01-07 @ 11:19 AM
Study NCT ID:
NCT06500351
Status:
RECRUITING
Last Update Posted:
2024-07-16
First Post:
2024-07-08
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Postpartum. Hypertension
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 90}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2024-06-25', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2024-07', 'completionDateStruct': {'date': '2025-09-01', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2024-07-12', 'studyFirstSubmitDate': '2024-07-08', 'studyFirstSubmitQcDate': '2024-07-08', 'lastUpdatePostDateStruct': {'date': '2024-07-16', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2024-07-15', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2025-06-25', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Renalase(rs10887800) Genotyping', 'timeFrame': '1 year', 'description': 'The presence of gene polymorphism whether homogenetic or heterogenetic'}], 'secondaryOutcomes': [{'measure': 'Leucocytes telomere length', 'timeFrame': '1 year', 'description': 'Measurement of the relative length of WBCs telomere in patints with postpartum hypertension'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Patients With Postpartum Hypertension']}, 'descriptionModule': {'briefSummary': 'This is an observertional study aimed at Study the association between Renalase(rs10887800) Genotyping \\& Leucocytes telomere length in patients with postpartum hypertension whether new onset( denovo) or persistent following pregnancy complicated by hypertension.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT'], 'maximumAge': '45 Years', 'minimumAge': '18 Years', 'genderBased': True, 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'Patients who were 18 years or above, and have a diagnosis of postpartum hypertension', 'genderDescription': 'only females are eligible for this study because of its relation to pregnancy.', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Patients who are18 years or above, and have a diagnosis of postpartum hypertension(regardless of where they received their antenatal care) attended to Sohag university hospitals\n\nExclusion Criteria:\n\n* All pregnant women with medical disorders in pregnancy other than Hypertensive disorders during pregnancy (e.g., sickle cell disease, heart disease, kidney and other connective tissues disorders) will be excluded from the study. Also we excluded measurements taken during scheduled or unscheduled surgical encounters given potential for interaction with anesthetic agents'}, 'identificationModule': {'nctId': 'NCT06500351', 'briefTitle': 'Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Postpartum. Hypertension', 'organization': {'class': 'OTHER', 'fullName': 'Sohag University'}, 'officialTitle': 'Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Patients With Postpartum Hypertension.', 'orgStudyIdInfo': {'id': 'Soh-Med-24-06-08PD'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'denovo postpartum hypertension', 'description': 'females with new onset hypertension after delivary'}, {'label': 'persitant postpartum hypertension', 'description': 'females with preexisting hypertension or preeclampsia that persist after delivery'}, {'label': 'control', 'description': 'females with normal postpartum blood pressure'}]}, 'contactsLocationsModule': {'locations': [{'city': 'Sohag', 'status': 'RECRUITING', 'country': 'Egypt', 'contacts': [{'name': 'Amera Morad Foad Hamdy, Assistant Professor', 'role': 'CONTACT', 'email': 'ameramoradfoad@gmail.com', 'phone': '+201006591449'}], 'facility': 'Sohag university hosoital', 'geoPoint': {'lat': 26.55695, 'lon': 31.69478}}], 'centralContacts': [{'name': 'Amera Morad Foad, assistant professor', 'role': 'CONTACT', 'email': 'ameramoradfoad@gmail.com', 'phone': '+201006591449'}], 'overallOfficials': [{'name': 'Amera Morad Foad, assistant professor', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Sohag University'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Sohag University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Assistant Professor of Medical Biochemistry', 'investigatorFullName': 'Amera Morad Foad', 'investigatorAffiliation': 'Sohag University'}}}}