Ignite Creation Date:
2025-12-24 @ 11:53 PM
Ignite Modification Date:
2026-01-01 @ 6:12 PM
Study NCT ID:
NCT04068051
Status:
COMPLETED
Last Update Posted:
2023-10-10
First Post:
2019-07-27
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Multimechanistic Treatment Over Time of Migraine Symptoms (MOVEMENT)
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D008881', 'term': 'Migraine Disorders'}], 'ancestors': [{'id': 'D051270', 'term': 'Headache Disorders, Primary'}, {'id': 'D020773', 'term': 'Headache Disorders'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}]}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'cstreicher@axsome.com', 'phone': '212-332-5061', 'title': 'Caroline Streicher, Vice President, Clinical Operations', 'organization': 'Axsome Therapeutics, Inc.'}, 'certainAgreement': {'piSponsorEmployee': False, 'restrictiveAgreement': True}}, 'adverseEventsModule': {'timeFrame': 'Adverse events were collected after administration of study drug through the final visit (up to 12 months). Any AE was monitored up to a maximum of 30 days after the final visit.', 'description': 'Safety Population includes all subjects who received at least one dose of study drug.', 'eventGroups': [{'id': 'EG000', 'title': 'AXS-07', 'description': 'AXS-07 (MoSEIC™ meloxicam and rizatriptan) taken by mouth for the acute treatment of migraine.', 'otherNumAtRisk': 706, 'deathsNumAtRisk': 706, 'otherNumAffected': 95, 'seriousNumAtRisk': 706, 'deathsNumAffected': 0, 'seriousNumAffected': 8}], 'otherEvents': [{'term': 'Nausea', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 88, 'numAffected': 40}], 'organSystem': 'Gastrointestinal disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Vomiting', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 48, 'numAffected': 33}], 'organSystem': 'Gastrointestinal disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Dizziness', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 45, 'numAffected': 22}], 'organSystem': 'Nervous system disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}], 'seriousEvents': [{'term': 'Mitral valve incompetence', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Cardiac disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Hiatus hernia', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Gastrointestinal disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Hepatitis acute', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Hepatobiliary disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Burns third degree', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Injury, poisoning and procedural complications', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Musculoskeletal procedural complication', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Injury, poisoning and procedural complications', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dicionary'}, {'term': 'Arthralgia', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Musculoskeletal and connective tissue disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Endometrial hyperplasia', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Reproductive system and breast disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Victim of crime', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Social circumstances', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}, {'term': 'Skin graft', 'stats': [{'groupId': 'EG000', 'numAtRisk': 706, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Surgical and medical procedures', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT', 'sourceVocabulary': 'MedDRA Dictionary'}], 'frequencyThreshold': '3'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Long-term Safety of Chronic Intermittent Use of AXS-07', 'denoms': [{'units': 'Participants', 'counts': [{'value': '706', 'groupId': 'OG000'}]}], 'groups': [{'id': 'OG000', 'title': 'AXS-07', 'description': 'AXS-07 (MoSEIC™ meloxicam and rizatriptan) taken by mouth for the acute treatment of migraine.'}], 'classes': [{'title': 'Subjects with any TEAEs', 'categories': [{'measurements': [{'value': '293', 'groupId': 'OG000'}]}]}, {'title': 'Subjects with suspected to be drug-related TEAEs', 'categories': [{'measurements': [{'value': '118', 'groupId': 'OG000'}]}]}, {'title': 'Subjects with serious TEAEs', 'categories': [{'measurements': [{'value': '8', 'groupId': 'OG000'}]}]}, {'title': 'Subjects with TEAEs that led to drug withdrawal', 'categories': [{'measurements': [{'value': '10', 'groupId': 'OG000'}]}]}, {'title': 'Subjects with TEAEs that led to withdrawal from study', 'categories': [{'measurements': [{'value': '13', 'groupId': 'OG000'}]}]}, {'title': 'Subjects with TEAEs that resulted in death', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'Up to 12 months', 'description': 'Long-term safety as measured by:\n\nSubjects with any TEAEs\n\nSubjects with suspected to be drug-related TEAEs\n\nSubjects with serious TEAEs\n\nSubjects with TEAEs that led to drug withdrawal\n\nSubjects with TEAEs that led to withdrawal from study\n\nSubjects with TEAEs that resulted in death', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'Safety Population includes all subjects who received at least one dose of study drug.'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'AXS-07', 'description': 'AXS-07 (MoSEIC™ meloxicam and rizatriptan) taken by mouth for the acute treatment of migraine.'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '706'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '138'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '568'}]}]}]}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '706', 'groupId': 'BG000'}]}], 'groups': [{'id': 'BG000', 'title': 'AXS-07', 'description': 'AXS-07 (MoSEIC™ meloxicam and rizatriptan) taken by mouth for the acute treatment of migraine.'}], 'measures': [{'title': 'Age, Continuous', 'classes': [{'categories': [{'measurements': [{'value': '42.0', 'spread': '10.94', 'groupId': 'BG000'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'years', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '580', 'groupId': 'BG000'}]}, {'title': 'Male', 'measurements': [{'value': '126', 'groupId': 'BG000'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Race (NIH/OMB)', 'classes': [{'categories': [{'title': 'American Indian or Alaska Native', 'measurements': [{'value': '7', 'groupId': 'BG000'}]}, {'title': 'Asian', 'measurements': [{'value': '12', 'groupId': 'BG000'}]}, {'title': 'Native Hawaiian or Other Pacific Islander', 'measurements': [{'value': '0', 'groupId': 'BG000'}]}, {'title': 'Black or African American', 'measurements': [{'value': '132', 'groupId': 'BG000'}]}, {'title': 'White', 'measurements': [{'value': '544', 'groupId': 'BG000'}]}, {'title': 'More than one race', 'measurements': [{'value': '9', 'groupId': 'BG000'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': '2', 'groupId': 'BG000'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}], 'populationDescription': 'Safety Population includes all subjects who received at least one dose of study drug.'}}, 'documentSection': {'largeDocumentModule': {'largeDocs': [{'date': '2019-10-17', 'size': 535971, 'label': 'Study Protocol and Statistical Analysis Plan', 'hasIcf': False, 'hasSap': True, 'filename': 'Prot_SAP_000.pdf', 'typeAbbrev': 'Prot_SAP', 'uploadDate': '2023-09-15T17:33', 'hasProtocol': True}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NA', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 706}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2019-07-06', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2023-09', 'dispFirstSubmitDate': '2021-09-14', 'completionDateStruct': {'date': '2020-09-22', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2023-09-15', 'studyFirstSubmitDate': '2019-07-27', 'dispFirstSubmitQcDate': '2021-09-14', 'resultsFirstSubmitDate': '2023-09-15', 'studyFirstSubmitQcDate': '2019-08-22', 'dispFirstPostDateStruct': {'date': '2021-09-16', 'type': 'ACTUAL'}, 'lastUpdatePostDateStruct': {'date': '2023-10-10', 'type': 'ACTUAL'}, 'resultsFirstSubmitQcDate': '2023-09-15', 'studyFirstPostDateStruct': {'date': '2019-08-28', 'type': 'ACTUAL'}, 'resultsFirstPostDateStruct': {'date': '2023-10-10', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2020-09-22', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Long-term Safety of Chronic Intermittent Use of AXS-07', 'timeFrame': 'Up to 12 months', 'description': 'Long-term safety as measured by:\n\nSubjects with any TEAEs\n\nSubjects with suspected to be drug-related TEAEs\n\nSubjects with serious TEAEs\n\nSubjects with TEAEs that led to drug withdrawal\n\nSubjects with TEAEs that led to withdrawal from study\n\nSubjects with TEAEs that resulted in death'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Axsome', 'AXS-07', 'MoSEIC™ meloxicam', 'rizatriptan'], 'conditions': ['Migraine']}, 'descriptionModule': {'briefSummary': 'MOVEMENT (Multimechanistic Treatment over Time of Migraine Symptoms) is a Phase 3 study to evaluate the long-term safety of chronic intermittent use of AXS-07 and to assess the effect of AXS-07 on migraine symptoms following repeated treatment of migraine attacks.', 'detailedDescription': 'This study is a Phase 3, multicenter, open-label, trial to evaluate the long-term safety and efficacy of intermittent chronic dosing with AXS-07 in subjects with migraine attacks. Eligible subjects will take AXS-07 following the onset of a migraine. Subjects will be treated for up to 12 months.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Has participated in a prior study with AXS-07 for the treatment of migraine\n\nExclusion Criteria:\n\n* Has previously received any investigational drug or device or investigational therapy within 30 days before Screening, other than AXS-07\n* Pregnant, breastfeeding, or planning to become pregnant or breastfeed during the study'}, 'identificationModule': {'nctId': 'NCT04068051', 'briefTitle': 'Multimechanistic Treatment Over Time of Migraine Symptoms (MOVEMENT)', 'organization': {'class': 'INDUSTRY', 'fullName': 'Axsome Therapeutics, Inc.'}, 'officialTitle': 'An Open-Label, Long-Term Study to Assess the Safety and Efficacy of AXS-07 (MoSEIC™ Meloxicam and Rizatriptan) for the Acute Treatment of Migraine in Adults', 'orgStudyIdInfo': {'id': 'AXS-07-302'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'AXS-07', 'interventionNames': ['Drug: AXS-07']}], 'interventions': [{'name': 'AXS-07', 'type': 'DRUG', 'description': 'AXS-07 (MoSEIC meloxicam and rizatriptan) taken by mouth for the acute treatment of migraine.', 'armGroupLabels': ['AXS-07']}]}, 'contactsLocationsModule': {'locations': [{'zip': '32516', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '32542', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '36608', 'city': 'Mobile', 'state': 'Alabama', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 30.69436, 'lon': -88.04305}}, {'zip': '85004', 'city': 'Phoenix', 'state': 'Arizona', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 33.44838, 'lon': -112.07404}}, {'zip': '91303', 'city': 'Canoga Park', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 34.20112, 'lon': -118.59814}}, {'zip': '92324', 'city': 'Colton', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 34.0739, 'lon': -117.31365}}, {'zip': '91316', 'city': 'Encino', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 34.15917, 'lon': -118.50119}}, {'zip': '90720', 'city': 'Los Alamitos', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 33.80307, 'lon': -118.07256}}, {'zip': '90017', 'city': 'Los Angeles', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '90048', 'city': 'Los Angeles', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '92103', 'city': 'San Diego', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'zip': '91978', 'city': 'Spring Valley', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 32.74477, 'lon': -116.99892}}, {'zip': '94598', 'city': 'Walnut Creek', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 37.90631, 'lon': -122.06496}}, {'zip': '33009', 'city': 'Hallandale', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 25.9812, 'lon': -80.14838}}, {'zip': '32256', 'city': 'Jacksonville', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '32055', 'city': 'Lake City', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 30.18968, 'lon': -82.63929}}, {'zip': '33467', 'city': 'Lake Worth', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 26.61708, 'lon': -80.07231}}, {'zip': '33155', 'city': 'Miami', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '34761', 'city': 'Ocoee', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 28.56917, 'lon': -81.54396}}, {'zip': '32801', 'city': 'Orlando', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 28.53834, 'lon': -81.37924}}, {'zip': '32174', 'city': 'Ormond Beach', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 29.28581, 'lon': -81.05589}}, {'zip': '33634', 'city': 'Tampa', 'state': 'Florida', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '30281', 'city': 'Stockbridge', 'state': 'Georgia', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 33.54428, 'lon': -84.23381}}, {'zip': '60201', 'city': 'Evanston', 'state': 'Illinois', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 42.04114, 'lon': -87.69006}}, {'zip': '40213', 'city': 'Louisville', 'state': 'Kentucky', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '02131', 'city': 'Boston', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02747', 'city': 'North Dartmouth', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 41.63899, 'lon': -70.97032}}, {'zip': '02451', 'city': 'Waltham', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 42.37649, 'lon': -71.23561}}, {'zip': '48104', 'city': 'Ann Arbor', 'state': 'Michigan', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 42.27756, 'lon': -83.74088}}, {'zip': '55402', 'city': 'Minneapolis', 'state': 'Minnesota', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 44.97997, 'lon': -93.26384}}, {'zip': '65810', 'city': 'Springfield', 'state': 'Missouri', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 37.21533, 'lon': -93.29824}}, {'zip': '89102', 'city': 'Las Vegas', 'state': 'Nevada', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 36.17497, 'lon': -115.13722}}, {'zip': '87102', 'city': 'Albuquerque', 'state': 'New Mexico', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '13104', 'city': 'Manlius', 'state': 'New York', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 43.00201, 'lon': -75.97686}}, {'zip': '14609', 'city': 'Rochester', 'state': 'New York', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 43.15478, 'lon': -77.61556}}, {'zip': '14221', 'city': 'Williamsville', 'state': 'New York', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 42.96395, 'lon': -78.73781}}, {'zip': '27262', 'city': 'High Point', 'state': 'North Carolina', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 35.95569, 'lon': -80.00532}}, {'zip': '45212', 'city': 'Cincinnati', 'state': 'Ohio', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 39.12711, 'lon': -84.51439}}, {'zip': '43213', 'city': 'Columbus', 'state': 'Ohio', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 39.96118, 'lon': -82.99879}}, {'zip': '73106', 'city': 'Oklahoma City', 'state': 'Oklahoma', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 35.46756, 'lon': -97.51643}}, {'zip': '97214', 'city': 'Portland', 'state': 'Oregon', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '97301', 'city': 'Salem', 'state': 'Oregon', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 44.9429, 'lon': -123.0351}}, {'zip': '19114', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '29406', 'city': 'Charleston', 'state': 'South Carolina', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 32.77632, 'lon': -79.93275}}, {'zip': '29464', 'city': 'Mt. Pleasant', 'state': 'South Carolina', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 32.79407, 'lon': -79.86259}}, {'zip': '37920', 'city': 'Knoxville', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 35.96064, 'lon': -83.92074}}, {'zip': '38119', 'city': 'Memphis', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 35.14953, 'lon': -90.04898}}, {'zip': '78731', 'city': 'Austin', 'state': 'Texas', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 30.26715, 'lon': -97.74306}}, {'zip': '84107', 'city': 'Salt Lake City', 'state': 'Utah', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 40.76078, 'lon': -111.89105}}, {'zip': '22911', 'city': 'Charlottesville', 'state': 'Virginia', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 38.02931, 'lon': -78.47668}}, {'zip': '98105', 'city': 'Seattle', 'state': 'Washington', 'country': 'United States', 'facility': 'Clinical Research Site', 'geoPoint': {'lat': 47.60621, 'lon': -122.33207}}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Axsome Therapeutics, Inc.', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}}