Ignite Creation Date:
2025-12-24 @ 11:49 PM
Ignite Modification Date:
2025-12-25 @ 9:43 PM
Study NCT ID:
NCT00382551
Status:
COMPLETED
Last Update Posted:
2009-01-30
First Post:
2006-09-28
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
The Effect of Beer, Red Wine and Fruit Juice on Blood Vessel Function in Persons With Cardiovascular Disease
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003327', 'term': 'Coronary Disease'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}], 'ancestors': [{'id': 'D017202', 'term': 'Myocardial Ischemia'}, {'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['EARLY_PHASE1'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'PREVENTION', 'interventionModel': 'CROSSOVER'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 49}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2006-10'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2009-01', 'lastUpdateSubmitDate': '2009-01-29', 'studyFirstSubmitDate': '2006-09-28', 'studyFirstSubmitQcDate': '2006-09-28', 'lastUpdatePostDateStruct': {'date': '2009-01-30', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2006-09-29', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Changes in flow-mediated vasodilation after 2 weeks intervention compared with baseline'}], 'secondaryOutcomes': [{'measure': 'Lipid status after 2 weeks intervention compared with baseline'}, {'measure': 'Effects in Coagulation factors after 2 weeks intervention'}, {'measure': 'Effects on markers of inflammation after 2 weeks intervention'}, {'measure': 'Effects on markers of endothelial function after 2 weeks intervention'}, {'measure': 'Changes in the overall antioxidant activity in plasma after 2 weeks intervention'}]}, 'conditionsModule': {'keywords': ['Alcohol', 'Red wine', 'Endothelial function', 'Flow-mediated vasodilation', 'Cardiovascular disease'], 'conditions': ['Coronary Heart Disease']}, 'descriptionModule': {'briefSummary': 'To study the effect of red wine, beer and fruit juice on endothelial function in patients with coronary Heart disease.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '30 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Men or postmenopausal women with stable coronary heart disease\n* Coronary heart disease should be verified by coronary angiography with at least 50% stenosis in at least one coronary vessel.\n\nExclusion Criteria:\n\n* Patients with myocardial infarction within the last tree months\n* Persons with a present or earlier alcohol abuse\n* Persons with a present or earlier drug abuse\n* Person with malign disease\n* Persons, that we consider unsuitable to carry through the examines.'}, 'identificationModule': {'nctId': 'NCT00382551', 'briefTitle': 'The Effect of Beer, Red Wine and Fruit Juice on Blood Vessel Function in Persons With Cardiovascular Disease', 'organization': {'class': 'OTHER', 'fullName': 'Aalborg University Hospital'}, 'officialTitle': 'The Effect of Alcohol and Polyphenolic Compounds on Endothelial Function', 'orgStudyIdInfo': {'id': 'VN-20060043'}}, 'armsInterventionsModule': {'interventions': [{'name': 'Moderate daily consumption of Red wine', 'type': 'BEHAVIORAL'}, {'name': 'Moderate daily consumption of beer', 'type': 'BEHAVIORAL'}, {'name': 'Moderate consumption of fruit juice rich in polyphenolics', 'type': 'BEHAVIORAL'}]}, 'contactsLocationsModule': {'locations': [{'zip': '9000', 'city': 'Aalborg', 'state': 'Aalborg', 'country': 'Denmark', 'facility': 'Department of Cardiology, Aalborg Hospital, Science and Innovation Center', 'geoPoint': {'lat': 57.048, 'lon': 9.9187}}], 'overallOfficials': [{'name': 'Erik B Schmidt, Professor', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Department of Cardiology, Aalborg Hospital , Aarhus University Hospital'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Aalborg University Hospital', 'class': 'OTHER'}}}}