Ignite Creation Date:
2025-12-24 @ 1:49 PM
Ignite Modification Date:
2026-01-02 @ 12:11 PM
Study NCT ID:
NCT01037595
Status:
COMPLETED
Last Update Posted:
2013-05-14
First Post:
2009-12-22
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Effect of Turmeric on Pruritus in Hemodialysis Patients
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D051436', 'term': 'Renal Insufficiency, Chronic'}, {'id': 'D011537', 'term': 'Pruritus'}], 'ancestors': [{'id': 'D051437', 'term': 'Renal Insufficiency'}, {'id': 'D007674', 'term': 'Kidney Diseases'}, {'id': 'D014570', 'term': 'Urologic Diseases'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D052801', 'term': 'Male Urogenital Diseases'}, {'id': 'D002908', 'term': 'Chronic Disease'}, {'id': 'D020969', 'term': 'Disease Attributes'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D012871', 'term': 'Skin Diseases'}, {'id': 'D017437', 'term': 'Skin and Connective Tissue Diseases'}, {'id': 'D012877', 'term': 'Skin Manifestations'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D003474', 'term': 'Curcumin'}], 'ancestors': [{'id': 'D036381', 'term': 'Diarylheptanoids'}, {'id': 'D006536', 'term': 'Heptanes'}, {'id': 'D000473', 'term': 'Alkanes'}, {'id': 'D006839', 'term': 'Hydrocarbons, Acyclic'}, {'id': 'D006838', 'term': 'Hydrocarbons'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D002396', 'term': 'Catechols'}, {'id': 'D010636', 'term': 'Phenols'}, {'id': 'D001555', 'term': 'Benzene Derivatives'}, {'id': 'D006841', 'term': 'Hydrocarbons, Aromatic'}, {'id': 'D006844', 'term': 'Hydrocarbons, Cyclic'}]}}, 'protocolSection': {'designModule': {'phases': ['EARLY_PHASE1'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 60}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2010-09'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2013-05', 'completionDateStruct': {'date': '2010-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2013-05-12', 'studyFirstSubmitDate': '2009-12-22', 'studyFirstSubmitQcDate': '2009-12-22', 'lastUpdatePostDateStruct': {'date': '2013-05-14', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2009-12-23', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2010-10', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'improvement in pruritus', 'timeFrame': '6 mo'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['hemodialysis', 'turmeric', 'pruritus'], 'conditions': ['End Stage Renal Failure']}, 'referencesModule': {'references': [{'pmid': '33283264', 'type': 'DERIVED', 'citation': 'Hercz D, Jiang SH, Webster AC. Interventions for itch in people with advanced chronic kidney disease. Cochrane Database Syst Rev. 2020 Dec 7;12(12):CD011393. doi: 10.1002/14651858.CD011393.pub2.'}]}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to see whether turmeric can be effective in treatment of pruritus in hemodialysis patients.', 'detailedDescription': 'pruritus is a common in hemodialysis patients and many treatment recommended for it . as turmeric has anti-inflammatory , anti-cytokine and anti-oxidant effect it may effective in treatment of uremic pruritus. thus we compared turmeric with placebo in this study'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '70 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Hemodialysis for more than 3 months\n* More than 18 years old\n* Pruritus\n\nExclusion Criteria:\n\n* Use other treatment for pruritus'}, 'identificationModule': {'nctId': 'NCT01037595', 'briefTitle': 'Effect of Turmeric on Pruritus in Hemodialysis Patients', 'organization': {'class': 'OTHER', 'fullName': 'Shiraz University of Medical Sciences'}, 'orgStudyIdInfo': {'id': '3441'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'turmeric', 'description': 'turmeric 500 mg tid orally for 8 weeks', 'interventionNames': ['Drug: turmeric']}, {'type': 'PLACEBO_COMPARATOR', 'label': 'plasebo', 'description': 'placebo tid orally for 8 weeks', 'interventionNames': ['Drug: placebo']}], 'interventions': [{'name': 'turmeric', 'type': 'DRUG', 'description': 'turmeric 500 md tid orally for 8 weeks', 'armGroupLabels': ['turmeric']}, {'name': 'placebo', 'type': 'DRUG', 'description': 'placebo 3 time orally for 8 weeks', 'armGroupLabels': ['plasebo']}, {'name': 'turmeric', 'type': 'DRUG', 'description': '500 mg tid orally for 8 weeks', 'armGroupLabels': ['turmeric']}]}, 'contactsLocationsModule': {'locations': [{'zip': '098', 'city': 'Shiraz', 'state': 'Fars', 'country': 'Iran', 'facility': 'Shiraz University Hemodialysis Center', 'geoPoint': {'lat': 29.61031, 'lon': 52.53113}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Shiraz University of Medical Sciences', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'associated professor of shiraz Shiraz University of Medical Sciences', 'investigatorFullName': 'Maryam Pakfetrat', 'investigatorAffiliation': 'Shiraz University of Medical Sciences'}}}}