Ignite Creation Date:
2025-12-24 @ 11:45 PM
Ignite Modification Date:
2025-12-25 @ 9:38 PM
Study NCT ID:
NCT00174551
Status:
UNKNOWN
Last Update Posted:
2006-09-11
First Post:
2005-09-09
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Feasibility Study: The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D013313', 'term': 'Stress Disorders, Post-Traumatic'}], 'ancestors': [{'id': 'D040921', 'term': 'Stress Disorders, Traumatic'}, {'id': 'D000068099', 'term': 'Trauma and Stressor Related Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D011224', 'term': 'Prazosin'}], 'ancestors': [{'id': 'D011799', 'term': 'Quinazolines'}, {'id': 'D006574', 'term': 'Heterocyclic Compounds, 2-Ring'}, {'id': 'D000072471', 'term': 'Heterocyclic Compounds, Fused-Ring'}, {'id': 'D006571', 'term': 'Heterocyclic Compounds'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'CROSSOVER'}, 'enrollmentInfo': {'count': 20}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'ACTIVE_NOT_RECRUITING', 'startDateStruct': {'date': '2003-11'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2005-09', 'completionDateStruct': {'date': '2005-11'}, 'lastUpdateSubmitDate': '2006-09-07', 'studyFirstSubmitDate': '2005-09-09', 'studyFirstSubmitQcDate': '2005-09-09', 'lastUpdatePostDateStruct': {'date': '2006-09-11', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2005-09-15', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Sleep time'}, {'measure': 'REM sleep time'}, {'measure': 'Nightmare frequency'}, {'measure': 'CGI'}], 'secondaryOutcomes': [{'measure': 'Distressed Awakenings frequency'}, {'measure': 'PCL-C'}]}, 'conditionsModule': {'conditions': ['Stress Disorders, Post-Traumatic']}, 'descriptionModule': {'briefSummary': 'Investigating the effect of prazosin for nighttime symptoms of civilian Posttraumatic Stress Disorder.', 'detailedDescription': 'Each subject will receive prazosin and placebo trials, the order randomized. Day and nighttime symptoms will be monitored.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* must meet DSM-IV criterion for PTSD\n\nExclusion Criteria:\n\n* Must not have untreated sleep apnea'}, 'identificationModule': {'nctId': 'NCT00174551', 'briefTitle': 'Feasibility Study: The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD', 'organization': {'class': 'OTHER', 'fullName': 'Rainier Associates'}, 'officialTitle': 'The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD', 'orgStudyIdInfo': {'id': '20031050'}}, 'armsInterventionsModule': {'interventions': [{'name': 'prazosin', 'type': 'DRUG'}]}, 'contactsLocationsModule': {'locations': [{'zip': '98467', 'city': 'Tacoma', 'state': 'Washington', 'country': 'United States', 'facility': 'Fletcher B. Taylor', 'geoPoint': {'lat': 47.25288, 'lon': -122.44429}}], 'overallOfficials': [{'name': 'Fletcher B Taylor, M.D.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Rainier Associates'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Rainier Associates', 'class': 'OTHER'}}}}