Ignite Creation Date:
2025-12-26 @ 11:13 PM
Ignite Modification Date:
2026-02-04 @ 5:16 PM
Study NCT ID:
NCT02692612
Status:
COMPLETED
Last Update Posted:
2022-05-19
First Post:
2015-11-04
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Effects of Power-velocity Muscle Characteristics During Ageing
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D055948', 'term': 'Sarcopenia'}], 'ancestors': [{'id': 'D009133', 'term': 'Muscular Atrophy'}, {'id': 'D020879', 'term': 'Neuromuscular Manifestations'}, {'id': 'D009461', 'term': 'Neurologic Manifestations'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D001284', 'term': 'Atrophy'}, {'id': 'D020763', 'term': 'Pathological Conditions, Anatomical'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 98}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2016-02', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2022-05', 'completionDateStruct': {'date': '2016-07', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2022-05-18', 'studyFirstSubmitDate': '2015-11-04', 'studyFirstSubmitQcDate': '2016-02-22', 'lastUpdatePostDateStruct': {'date': '2022-05-19', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2016-02-26', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2016-07', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Differences in power-velocity characteristics during ageing', 'timeFrame': '1x at baseline (cross sectional study)', 'description': 'peak power and rate of power development (slope) at different velocities during knee extension movement and cyclic multijoint leg press movement compared between young and old people'}], 'secondaryOutcomes': [{'measure': 'Reliability of strength tests on regular and recumbent bike.', 'timeFrame': '1x at baseline (cross sectional study)', 'description': 'reliability of peak power and rate of power development outcomes measured twice within a period of 2 weeks'}, {'measure': 'Differences in muscle fascicle characteristics during ageing.', 'timeFrame': '1x at baseline (cross sectional study)', 'description': 'Differences between young and old people of fascicle shortening velocity during dynamic leg press movements measured via dynamic ultrasound'}, {'measure': 'Differences in muscle activation during ageing.', 'timeFrame': '1x at baseline (cross sectional study)', 'description': 'Differences in muscle activation pattern during dynamic leg press movements measured via muscle electromyography'}]}, 'conditionsModule': {'conditions': ['Sarcopenia']}, 'descriptionModule': {'briefSummary': 'The purpose of this project is to investigate the age-related differences in force-velocity muscle characteristics during isolated knee extensions variable in speed and load, during cyclic movements on a usual and recumbent bike variable in speed and velocity development and a functional test battery with healthy participants aged between 20-80 years.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '20 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'young (20-40y) middle-aged (40-60y) old (60-80y)', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* healthy volunteers age 20 to 80 years\n\nExclusion Criteria:\n\n* Knee or hip prothesis\n* Systematic training\n* Cardiovascular disease\n* Acute lower back pain\n* Acute knee pain\n* Dementia'}, 'identificationModule': {'nctId': 'NCT02692612', 'briefTitle': 'Effects of Power-velocity Muscle Characteristics During Ageing', 'organization': {'class': 'OTHER', 'fullName': 'Universitaire Ziekenhuizen KU Leuven'}, 'orgStudyIdInfo': {'id': 's58633'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Young'}, {'label': 'Middle-Aged'}, {'label': 'Old'}]}, 'contactsLocationsModule': {'locations': [{'zip': '3000', 'city': 'Leuven', 'country': 'Belgium', 'facility': 'Faculty of kinesiology and rehabilitation sciences', 'geoPoint': {'lat': 50.87959, 'lon': 4.70093}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Universitaire Ziekenhuizen KU Leuven', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}