Ignite Creation Date:
2025-12-24 @ 11:42 PM
Ignite Modification Date:
2026-02-17 @ 10:46 PM
Study NCT ID:
NCT03000751
Status:
COMPLETED
Last Update Posted:
2024-03-08
First Post:
2016-12-12
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
CT DOSE Collaboratory
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'rebecca.smith-bindman@ucsf.edu', 'phone': '415-353-4946', 'title': 'Rebecca Smith-Bindman, MD', 'organization': 'University of California San Francisco'}, 'certainAgreement': {'piSponsorEmployee': False, 'restrictiveAgreement': False}}, 'adverseEventsModule': {'timeFrame': 'Adverse events were not collected.', 'description': 'Adverse event data were not reported in this study. Study data were collected from consecutive patients who underwent a standard of care procedure (CT imaging). No tests, treatments, or interactions with any patients were performed as part of this study. There was no way to capture, nor any need to capture for the purpose of our research, adverse events related to their imaging procedures.', 'eventGroups': [{'id': 'EG000', 'title': 'Track A', 'description': 'Simple Audit Report In-Person Meeting Multi-Component Intervention\n\nSimple Audit Report: The simple audit provides comparison and feedback on radiation doses.\n\nMulti-Component Intervention: The multi-component intervention gives tailored feedback on needed changes plus guidance using quality improvement methods that facilitate organizational change. Provides access to experts, detailed audit, collaborative calls, and site visits (as needed).\n\nIn-Person Meeting: Collaborator meeting with an emphasis on quality improvement.', 'otherNumAtRisk': 0, 'deathsNumAtRisk': 0, 'otherNumAffected': 0, 'seriousNumAtRisk': 0, 'deathsNumAffected': 0, 'seriousNumAffected': 0}, {'id': 'EG001', 'title': 'Track B', 'description': 'Simple Audit Report In-Person Meeting Multi-Component Intervention\n\nSimple Audit Report: The simple audit provides comparison and feedback on radiation doses.\n\nMulti-Component Intervention: The multi-component intervention gives tailored feedback on needed changes plus guidance using quality improvement methods that facilitate organizational change. Provides access to experts, detailed audit, collaborative calls, and site visits (as needed).\n\nIn-Person Meeting: Collaborator meeting with an emphasis on quality improvement.', 'otherNumAtRisk': 0, 'deathsNumAtRisk': 0, 'otherNumAffected': 0, 'seriousNumAtRisk': 0, 'deathsNumAffected': 0, 'seriousNumAffected': 0}, {'id': 'EG002', 'title': 'Track C', 'description': 'Simple Audit Report Multi-Component Intervention\n\nSimple Audit Report: The simple audit provides comparison and feedback on radiation doses.\n\nMulti-Component Intervention: The multi-component intervention gives tailored feedback on needed changes plus guidance using quality improvement methods that facilitate organizational change. Provides access to experts, detailed audit, collaborative calls, and site visits (as needed).', 'otherNumAtRisk': 0, 'deathsNumAtRisk': 0, 'otherNumAffected': 0, 'seriousNumAtRisk': 0, 'deathsNumAffected': 0, 'seriousNumAffected': 0}], 'frequencyThreshold': '0'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Change in Mean Effective Dose (ED)', 'denoms': [{'units': 'Participants', 'counts': [{'value': 'NA', 'groupId': 'OG000'}, {'value': 'NA', 'groupId': 'OG001'}]}, {'units': 'CT scans', 'counts': [{'value': '251409', 'groupId': 'OG000'}, {'value': '207576', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention.'}, {'id': 'OG001', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention.'}], 'classes': [{'title': 'Abdomen', 'categories': [{'measurements': [{'value': '-0.13', 'groupId': 'OG000', 'lowerLimit': '-0.24', 'upperLimit': '-0.02'}, {'value': '-0.81', 'groupId': 'OG001', 'lowerLimit': '-0.99', 'upperLimit': '-0.64'}]}]}, {'title': 'Chest', 'categories': [{'measurements': [{'value': '-0.14', 'groupId': 'OG000', 'lowerLimit': '-0.23', 'upperLimit': '-0.05'}, {'value': '-0.26', 'groupId': 'OG001', 'lowerLimit': '-0.40', 'upperLimit': '-0.11'}]}]}, {'title': 'Combined abdomen and chest', 'categories': [{'measurements': [{'value': '-0.88', 'groupId': 'OG000', 'lowerLimit': '-1.18', 'upperLimit': '-0.57'}, {'value': '-2.04', 'groupId': 'OG001', 'lowerLimit': '-2.55', 'upperLimit': '-1.53'}]}]}, {'title': 'Head', 'categories': [{'measurements': [{'value': '-0.01', 'groupId': 'OG000', 'lowerLimit': '-0.06', 'upperLimit': '0.04'}, {'value': '-0.05', 'groupId': 'OG001', 'lowerLimit': '-0.13', 'upperLimit': '0.02'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the mean effective dose after the simple audit and multi-component interventions (MCI) in comparison to before the audit and multi-component interventions. The numbers given below reflect absolute change in mean dose (in millisieverts) relative to the baseline period.', 'unitOfMeasure': 'Millisieverts (mSv)', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'CT scans', 'denomUnitsSelected': 'CT scans', 'populationDescription': 'The unit of analysis is CT scans; there were no data collected at the participant level. We excluded scans obtained during transition ("washout") periods immediately following each intervention. The numbers given below reflect absolute change in mean dose (in millisieverts) relative to the baseline period.'}, {'type': 'PRIMARY', 'title': 'Percentage of CT Scans With an Effective Dose Above Benchmark', 'denoms': [{'units': 'Participants', 'counts': [{'value': 'NA', 'groupId': 'OG000'}, {'value': 'NA', 'groupId': 'OG001'}, {'value': 'NA', 'groupId': 'OG002'}]}, {'units': 'CT scans', 'counts': [{'value': '526439', 'groupId': 'OG000'}, {'value': '251409', 'groupId': 'OG001'}, {'value': '207576', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Baseline Period', 'description': 'Reflects CT scans analyzed during a baseline period of usual care (before intervention).'}, {'id': 'OG001', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention.'}, {'id': 'OG002', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention.'}], 'classes': [{'title': 'Abdomen', 'categories': [{'measurements': [{'value': '24.7', 'groupId': 'OG000'}, {'value': '24.7', 'groupId': 'OG001'}, {'value': '22.2', 'groupId': 'OG002'}]}]}, {'title': 'Chest', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '25.5', 'groupId': 'OG001'}, {'value': '24.9', 'groupId': 'OG002'}]}]}, {'title': 'Combined chest and abdomen', 'categories': [{'measurements': [{'value': '26.7', 'groupId': 'OG000'}, {'value': '23', 'groupId': 'OG001'}, {'value': '18.8', 'groupId': 'OG002'}]}]}, {'title': 'Head', 'categories': [{'measurements': [{'value': '26.2', 'groupId': 'OG000'}, {'value': '26', 'groupId': 'OG001'}, {'value': '21.8', 'groupId': 'OG002'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the percentage of examinations with an effective dose above the benchmark after the simple audit and after multi-component intervention (MCI) in comparison to doses before the audit and MCI. The benchmark for each anatomic area is defined as the 75th percentile of the dose distribution during the pre-intervention (baseline) period.', 'unitOfMeasure': 'Percent of CT scans over benchmark', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'CT scans', 'denomUnitsSelected': 'CT scans', 'populationDescription': 'The unit of analysis is CT scans; there were no data collected at the participant level. We excluded scans obtained during transition ("washout") periods immediately following each intervention.'}, {'type': 'SECONDARY', 'title': 'Mean Dose Length Product', 'denoms': [{'units': 'Participants', 'counts': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Baseline Period', 'description': 'Reflects CT scans analyzed during a baseline period of usual care (before intervention).'}, {'id': 'OG001', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention.'}, {'id': 'OG002', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention.'}], 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the dose length product after the audit and MCI in comparison to before the audit and MCI.', 'reportingStatus': 'POSTED', 'populationDescription': 'Data were not collected.'}, {'type': 'SECONDARY', 'title': 'Proportion of CT Scans With a Dose Length Product Above Benchmark', 'denoms': [{'units': 'Participants', 'counts': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}, {'value': '0', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Baseline Period', 'description': 'Reflects CT scans analyzed during a baseline period of usual care (before intervention).'}, {'id': 'OG001', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention.'}, {'id': 'OG002', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention.'}], 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the proportion of examinations with a dose length product above the benchmark after the audit and after the MCI in comparison to doses before the audit and MCI. The benchmark for each anatomic area is defined as the 75th percentile of the dose distribution during the pre intervention period.', 'reportingStatus': 'POSTED', 'populationDescription': 'Data were not collected.'}, {'type': 'SECONDARY', 'title': 'Change in Mean Volume Computed Tomography Dose Index (CTDIvol)', 'denoms': [{'units': 'Participants', 'counts': [{'value': 'NA', 'groupId': 'OG000'}, {'value': 'NA', 'groupId': 'OG001'}]}, {'units': 'CT scans', 'counts': [{'value': '251409', 'groupId': 'OG000'}, {'value': '207576', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention.'}, {'id': 'OG001', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention.'}], 'classes': [{'title': 'Abdomen', 'categories': [{'measurements': [{'value': '0.09', 'groupId': 'OG000', 'lowerLimit': '0.01', 'upperLimit': '0.16'}, {'value': '0.03', 'groupId': 'OG001', 'lowerLimit': '-0.10', 'upperLimit': '0.15'}]}]}, {'title': 'Chest', 'categories': [{'measurements': [{'value': '0.04', 'groupId': 'OG000', 'lowerLimit': '-0.07', 'upperLimit': '0.14'}, {'value': '-0.11', 'groupId': 'OG001', 'lowerLimit': '-0.29', 'upperLimit': '0.06'}]}]}, {'title': 'Combined abdomen and chest', 'categories': [{'measurements': [{'value': '-0.05', 'groupId': 'OG000', 'lowerLimit': '-0.18', 'upperLimit': '0.08'}, {'value': '-0.42', 'groupId': 'OG001', 'lowerLimit': '-0.64', 'upperLimit': '-0.20'}]}]}, {'title': 'Head', 'categories': [{'measurements': [{'value': '0.44', 'groupId': 'OG000', 'lowerLimit': '0.27', 'upperLimit': '0.62'}, {'value': '-0.56', 'groupId': 'OG001', 'lowerLimit': '-0.85', 'upperLimit': '-0.27'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the mean volume CT dose index (CTDIvol) from before versus after the audit and MCI intervention. CTDIvol (in units of milligray, mGy) is a measure of radiation dose, reflecting the amount of radiation imparted per CT slice by the scanner. Higher CTDIvol signifies more radiation dose. In general, a reduction in CTDIvol would be a sign of quality improvement, minimizing excess radiation exposure to the patient.', 'unitOfMeasure': 'Milligrays (mGy)', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'CT scans', 'denomUnitsSelected': 'CT scans', 'populationDescription': 'The unit of analysis is CT scans; there were no data collected at the participant level. We excluded scans obtained during transition ("washout") periods immediately following each intervention. The numbers given below reflect absolute change in mean dose (in milligray, mGy) relative to the baseline period.'}, {'type': 'SECONDARY', 'title': 'Percentage of CT Scans With a CTDIvol Above Benchmark', 'denoms': [{'units': 'Participants', 'counts': [{'value': 'NA', 'groupId': 'OG000'}, {'value': 'NA', 'groupId': 'OG001'}, {'value': 'NA', 'groupId': 'OG002'}]}, {'units': 'CT scans', 'counts': [{'value': '526439', 'groupId': 'OG000'}, {'value': '251409', 'groupId': 'OG001'}, {'value': '207576', 'groupId': 'OG002'}]}], 'groups': [{'id': 'OG000', 'title': 'Baseline Period', 'description': 'Reflects CT scans analyzed during a baseline period of usual care (before intervention).'}, {'id': 'OG001', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention.'}, {'id': 'OG002', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention.'}], 'classes': [{'title': 'Abdomen', 'categories': [{'measurements': [{'value': '24.5', 'groupId': 'OG000'}, {'value': '24.9', 'groupId': 'OG001'}, {'value': '24.1', 'groupId': 'OG002'}]}]}, {'title': 'Chest', 'categories': [{'measurements': [{'value': '26', 'groupId': 'OG000'}, {'value': '25.8', 'groupId': 'OG001'}, {'value': '24.1', 'groupId': 'OG002'}]}]}, {'title': 'Combined chest and abdomen', 'categories': [{'measurements': [{'value': '23.6', 'groupId': 'OG000'}, {'value': '22.7', 'groupId': 'OG001'}, {'value': '19.9', 'groupId': 'OG002'}]}]}, {'title': 'Head', 'categories': [{'measurements': [{'value': '24.4', 'groupId': 'OG000'}, {'value': '25.0', 'groupId': 'OG001'}, {'value': '17.9', 'groupId': 'OG002'}]}]}], 'paramType': 'NUMBER', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the percentage of examinations with a CTDIvol above the benchmark after the audit and after multicomponent intervention in comparison to doses before the audit and multicomponent intervention. The benchmark for each anatomic area is defined as the 75th percentile of the dose distribution during the pre intervention period.', 'unitOfMeasure': 'Percentage of CT scans', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'CT scans', 'denomUnitsSelected': 'CT scans', 'populationDescription': 'The unit of analysis is CT scans; there were no data collected at the participant level. We excluded scans obtained during transition ("washout") periods immediately following each intervention.'}, {'type': 'SECONDARY', 'title': 'Change in Mean Organ Doses: Brain Dose for Head CT; Lung Dose For Chest CT; Colon and Liver Dose for Abdomen CT', 'denoms': [{'units': 'Participants', 'counts': [{'value': 'NA', 'groupId': 'OG000'}, {'value': 'NA', 'groupId': 'OG001'}]}, {'units': 'CT scans', 'counts': [{'value': '251409', 'groupId': 'OG000'}, {'value': '207576', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention.'}, {'id': 'OG001', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention.'}], 'classes': [{'title': 'Abdomen (colon organ dose)', 'categories': [{'measurements': [{'value': '-6.0', 'groupId': 'OG000', 'lowerLimit': '-6.9', 'upperLimit': '-5.0'}, {'value': '-12.2', 'groupId': 'OG001', 'lowerLimit': '-13.8', 'upperLimit': '-10.6'}]}]}, {'title': 'Chest (lung organ dose)', 'categories': [{'measurements': [{'value': '-2.1', 'groupId': 'OG000', 'lowerLimit': '-2.8', 'upperLimit': '-1.5'}, {'value': '-3.7', 'groupId': 'OG001', 'lowerLimit': '-4.7', 'upperLimit': '-2.7'}]}]}, {'title': 'Combined chest and abdomen (lung organ dose)', 'categories': [{'measurements': [{'value': '-16.0', 'groupId': 'OG000', 'lowerLimit': '-18.2', 'upperLimit': '-13.8'}, {'value': '-30.1', 'groupId': 'OG001', 'lowerLimit': '-33.8', 'upperLimit': '-26.4'}]}]}, {'title': 'Combined chest and abdomen (colon organ dose)', 'categories': [{'measurements': [{'value': '-13.0', 'groupId': 'OG000', 'lowerLimit': '-14.5', 'upperLimit': '-11.6'}, {'value': '-17.6', 'groupId': 'OG001', 'lowerLimit': '-20.0', 'upperLimit': '-15.1'}]}]}, {'title': 'Head (brain organ dose)', 'categories': [{'measurements': [{'value': '-2.9', 'groupId': 'OG000', 'lowerLimit': '-6.4', 'upperLimit': '0.70'}, {'value': '-7.5', 'groupId': 'OG001', 'lowerLimit': '-13.3', 'upperLimit': '-1.7'}]}]}], 'paramType': 'MEAN', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in organ doses after the simple audit and multi-component interventions (MCI) in comparison to before the audit and multi-component interventions. The numbers given below reflect absolute change in mean dose (in millisieverts) relative to the baseline period.', 'unitOfMeasure': 'Milligrays (mGy)', 'dispersionType': '95% Confidence Interval', 'reportingStatus': 'POSTED', 'typeUnitsAnalyzed': 'CT scans', 'denomUnitsSelected': 'CT scans', 'populationDescription': 'The unit of analysis is CT scans; there were no data collected at the participant level. We excluded scans obtained during transition ("washout") periods immediately following each intervention. The numbers given below reflect absolute change in mean dose (in millisieverts) relative to the baseline period.'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Track A', 'description': 'Track A received the simple audit intervention at week 40 and the multi-component intervention at week 68.\n\nThe simple audit provided feedback on radiation doses including comparison with other participating sites. The multi-component intervention gave tailored, actionable feedback on needed changes in addition to a 7-week quality improvement collaborative that included guidance on quality improvement methods, webinars, interactive lectures by experts, case reviews, and best practices sharing.'}, {'id': 'FG001', 'title': 'Track B', 'description': 'Track B received the simple audit intervention at week 44 and the multi-component intervention at week 74.\n\nThe simple audit provided feedback on radiation doses including comparison with other participating sites. The multi-component intervention gave tailored, actionable feedback on needed changes in addition to a 7-week quality improvement collaborative that included guidance on quality improvement methods, webinars, interactive lectures by experts, case reviews, and best practices sharing.'}, {'id': 'FG002', 'title': 'Track C', 'description': 'Track C received the simple audit intervention at week 53 and the multi-component intervention at week 81.\n\nThe simple audit provided feedback on radiation doses including comparison with other participating sites. The multi-component intervention gave tailored, actionable feedback on needed changes in addition to a 7-week quality improvement collaborative that included guidance on quality improvement methods, webinars, interactive lectures by experts, case reviews, and best practices sharing.'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'comment': 'Track A Imaging facilities: 32', 'groupId': 'FG000', 'numUnits': '327,462', 'numSubjects': '251607'}, {'comment': 'Track B Imaging facilities: 29', 'groupId': 'FG001', 'numUnits': '306,825', 'numSubjects': '229022'}, {'comment': 'Track C Imaging facilities: 39', 'groupId': 'FG002', 'numUnits': '522,370', 'numSubjects': '383451'}]}, {'type': 'COMPLETED', 'comment': 'All subjects started and completed each track. Note, however, that patients were enrolled passively. The unit of analysis was CT scans (not individual subjects), and all eligible CT scans performed during each study period were included.', 'achievements': [{'groupId': 'FG000', 'numUnits': '327,462', 'numSubjects': '251607'}, {'groupId': 'FG001', 'numUnits': '306,825', 'numSubjects': '229022'}, {'groupId': 'FG002', 'numUnits': '522,370', 'numSubjects': '383451'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numUnits': 'NA', 'numSubjects': '0'}, {'groupId': 'FG001', 'numUnits': 'NA', 'numSubjects': '0'}, {'groupId': 'FG002', 'numUnits': 'NA', 'numSubjects': '0'}]}]}], 'typeUnitsAnalyzed': 'CT scans', 'preAssignmentDetails': 'Study subjects were passively enrolled in this study; we had a waiver of informed consent and there was no direct contact with subjects. We have listed the number of unique subjects enrolled into each track; however, ALL ANALYSES WERE PERFORMED AT THE LEVEL OF THE CT SCAN, not at the individual subject level.'}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': 'NA', 'groupId': 'BG000'}, {'value': 'NA', 'groupId': 'BG001'}, {'value': 'NA', 'groupId': 'BG002'}, {'value': 'NA', 'groupId': 'BG003'}]}, {'units': 'CT scans', 'counts': [{'value': '526439', 'groupId': 'BG000'}, {'value': '251409', 'groupId': 'BG001'}, {'value': '207576', 'groupId': 'BG002'}, {'value': '985424', 'groupId': 'BG003'}]}], 'groups': [{'id': 'BG000', 'title': 'Baseline Period', 'description': 'Reflects CT scans analyzed during a baseline period of usual care (before intervention). The duration of this period differed by randomization Track (A, B, or C).'}, {'id': 'BG001', 'title': 'Simple Audit Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the simple audit report intervention. The duration of this period differed by randomization Track (A, B, or C).'}, {'id': 'BG002', 'title': 'Multi-component Intervention Period', 'description': 'Reflects CT scans analyzed after receiving the multi-component intervention. The duration of this period differed by randomization Track (A, B, or C).'}, {'id': 'BG003', 'title': 'Total', 'description': 'Total of all reporting groups'}], 'measures': [{'title': 'Age, Customized', 'classes': [{'title': '18-29 years', 'categories': [{'measurements': [{'value': '40022', 'groupId': 'BG000'}, {'value': '18468', 'groupId': 'BG001'}, {'value': '15391', 'groupId': 'BG002'}, {'value': '73881', 'groupId': 'BG003'}]}]}, {'title': '30-39 years', 'categories': [{'measurements': [{'value': '45880', 'groupId': 'BG000'}, {'value': '21198', 'groupId': 'BG001'}, {'value': '17615', 'groupId': 'BG002'}, {'value': '84693', 'groupId': 'BG003'}]}]}, {'title': '40-49 years', 'categories': [{'measurements': [{'value': '64299', 'groupId': 'BG000'}, {'value': '29492', 'groupId': 'BG001'}, {'value': '24351', 'groupId': 'BG002'}, {'value': '118142', 'groupId': 'BG003'}]}]}, {'title': '50-59 years', 'categories': [{'measurements': [{'value': '98457', 'groupId': 'BG000'}, {'value': '46589', 'groupId': 'BG001'}, {'value': '37951', 'groupId': 'BG002'}, {'value': '182997', 'groupId': 'BG003'}]}]}, {'title': '60-69 years', 'categories': [{'measurements': [{'value': '114161', 'groupId': 'BG000'}, {'value': '54155', 'groupId': 'BG001'}, {'value': '44102', 'groupId': 'BG002'}, {'value': '212418', 'groupId': 'BG003'}]}]}, {'title': '70-79 years', 'categories': [{'measurements': [{'value': '92374', 'groupId': 'BG000'}, {'value': '45969', 'groupId': 'BG001'}, {'value': '39073', 'groupId': 'BG002'}, {'value': '177416', 'groupId': 'BG003'}]}]}, {'title': '80 years and older', 'categories': [{'measurements': [{'value': '71246', 'groupId': 'BG000'}, {'value': '35538', 'groupId': 'BG001'}, {'value': '29093', 'groupId': 'BG002'}, {'value': '135877', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_UNITS', 'description': 'Patient age distribution by decade.', 'unitOfMeasure': 'CT scans', 'denomUnitsSelected': 'CT scans'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '278841', 'groupId': 'BG000'}, {'value': '132772', 'groupId': 'BG001'}, {'value': '110088', 'groupId': 'BG002'}, {'value': '521701', 'groupId': 'BG003'}]}, {'title': 'Male', 'measurements': [{'value': '247598', 'groupId': 'BG000'}, {'value': '118637', 'groupId': 'BG001'}, {'value': '97488', 'groupId': 'BG002'}, {'value': '463723', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_UNITS', 'unitOfMeasure': 'CT scans', 'denomUnitsSelected': 'CT scans'}, {'title': 'Ethnicity (NIH/OMB)', 'classes': [{'categories': [{'title': 'Hispanic or Latino', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'Not Hispanic or Latino', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_UNITS', 'description': 'Race and Ethnicity data not collected', 'unitOfMeasure': 'CT scans', 'denomUnitsSelected': 'CT scans'}, {'title': 'Race (NIH/OMB)', 'classes': [{'categories': [{'title': 'American Indian or Alaska Native', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'Asian', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'Native Hawaiian or Other Pacific Islander', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'Black or African American', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'White', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'More than one race', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}, {'title': 'Unknown or Not Reported', 'measurements': [{'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG000'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG001'}, {'value': 'NA', 'comment': 'Race and Ethnicity data not collected', 'groupId': 'BG002'}, {'value': 'NA', 'comment': 'Total not calculated because data are not available (NA) in one or more arms.', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_UNITS', 'description': 'Race and Ethnicity data not collected', 'unitOfMeasure': 'CT scans', 'denomUnitsSelected': 'CT scans'}, {'title': 'Type of scan', 'classes': [{'title': 'Abdomen', 'categories': [{'measurements': [{'value': '185671', 'groupId': 'BG000'}, {'value': '87518', 'groupId': 'BG001'}, {'value': '72084', 'groupId': 'BG002'}, {'value': '345273', 'groupId': 'BG003'}]}]}, {'title': 'Chest', 'categories': [{'measurements': [{'value': '143120', 'groupId': 'BG000'}, {'value': '69678', 'groupId': 'BG001'}, {'value': '56410', 'groupId': 'BG002'}, {'value': '269208', 'groupId': 'BG003'}]}]}, {'title': 'Combined abdomen and chest', 'categories': [{'measurements': [{'value': '30689', 'groupId': 'BG000'}, {'value': '14784', 'groupId': 'BG001'}, {'value': '14416', 'groupId': 'BG002'}, {'value': '59889', 'groupId': 'BG003'}]}]}, {'title': 'Head', 'categories': [{'measurements': [{'value': '166959', 'groupId': 'BG000'}, {'value': '79429', 'groupId': 'BG001'}, {'value': '64666', 'groupId': 'BG002'}, {'value': '311054', 'groupId': 'BG003'}]}]}], 'paramType': 'COUNT_OF_UNITS', 'description': 'Anatomical region imaged.', 'unitOfMeasure': 'CT scans', 'denomUnitsSelected': 'CT scans'}, {'title': 'Age, by type of scan', 'classes': [{'title': 'Abdomen', 'categories': [{'measurements': [{'value': '56.0', 'spread': '18.2', 'groupId': 'BG000'}, {'value': '56.3', 'spread': '18.3', 'groupId': 'BG001'}, {'value': '56.4', 'spread': '18.3', 'groupId': 'BG002'}, {'value': '56.2', 'spread': '18.3', 'groupId': 'BG003'}]}]}, {'title': 'Chest', 'categories': [{'measurements': [{'value': '61.6', 'spread': '15.3', 'groupId': 'BG000'}, {'value': '62.1', 'spread': '15.2', 'groupId': 'BG001'}, {'value': '62.0', 'spread': '15.2', 'groupId': 'BG002'}, {'value': '61.8', 'spread': '15.2', 'groupId': 'BG003'}]}]}, {'title': 'Combined abdomen and chest', 'categories': [{'measurements': [{'value': '62.5', 'spread': '15.3', 'groupId': 'BG000'}, {'value': '62.8', 'spread': '15.5', 'groupId': 'BG001'}, {'value': '63.4', 'spread': '15.4', 'groupId': 'BG002'}, {'value': '62.8', 'spread': '15.4', 'groupId': 'BG003'}]}]}, {'title': 'Head', 'categories': [{'measurements': [{'value': '60.1', 'spread': '19.9', 'groupId': 'BG000'}, {'value': '60.7', 'spread': '19.9', 'groupId': 'BG001'}, {'value': '60.6', 'spread': '19.9', 'groupId': 'BG002'}, {'value': '60.4', 'spread': '19.9', 'groupId': 'BG003'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'Years', 'dispersionType': 'STANDARD_DEVIATION', 'denomUnitsSelected': 'CT scans'}, {'title': 'Patient diameter', 'classes': [{'title': 'Abdomen', 'categories': [{'measurements': [{'value': '30.7', 'spread': '4.6', 'groupId': 'BG000'}, {'value': '30.8', 'spread': '4.7', 'groupId': 'BG001'}, {'value': '30.9', 'spread': '4.7', 'groupId': 'BG002'}, {'value': '30.8', 'spread': '4.7', 'groupId': 'BG003'}]}]}, {'title': 'Chest', 'categories': [{'measurements': [{'value': '28.9', 'spread': '4.9', 'groupId': 'BG000'}, {'value': '29.0', 'spread': '4.9', 'groupId': 'BG001'}, {'value': '28.9', 'spread': '5.1', 'groupId': 'BG002'}, {'value': '28.9', 'spread': '5.0', 'groupId': 'BG003'}]}]}, {'title': 'Combined abdomen and chest', 'categories': [{'measurements': [{'value': '29.7', 'spread': '4.1', 'groupId': 'BG000'}, {'value': '29.5', 'spread': '4.2', 'groupId': 'BG001'}, {'value': '29.7', 'spread': '4.2', 'groupId': 'BG002'}, {'value': '29.7', 'spread': '4.2', 'groupId': 'BG003'}]}]}, {'title': 'Head', 'categories': [{'measurements': [{'value': '17.1', 'spread': '1.5', 'groupId': 'BG000'}, {'value': '17.1', 'spread': '1.5', 'groupId': 'BG001'}, {'value': '17.2', 'spread': '1.5', 'groupId': 'BG002'}, {'value': '17.1', 'spread': '1.5', 'groupId': 'BG003'}]}]}], 'paramType': 'MEAN', 'description': 'Patient diameter, as measured in cm on mid-scan images, is an indicator of patient size.', 'unitOfMeasure': 'Centimeters (cm)', 'dispersionType': 'STANDARD_DEVIATION', 'denomUnitsSelected': 'CT scans'}], 'typeUnitsAnalyzed': 'CT scans', 'populationDescription': 'THE UNIT OF ANALYSIS IS CT SCANS, NOT PATIENTS. The arms in this section do not reflect the randomization tracks (A,B,C) but rather study periods: before intervention; after simple audit; after multi-component intervention. We excluded scans obtained during transition ("washout") periods immediately following each intervention. The numbers here reflect unique CT scans, not unique patients. Units are not counted more than once.'}}, 'documentSection': {'largeDocumentModule': {'largeDocs': [{'date': '2017-08-29', 'size': 548739, 'label': 'Study Protocol and Statistical Analysis Plan', 'hasIcf': False, 'hasSap': True, 'filename': 'Prot_SAP_002.pdf', 'typeAbbrev': 'Prot_SAP', 'uploadDate': '2023-09-01T13:21', 'hasProtocol': True}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'HEALTH_SERVICES_RESEARCH', 'interventionModel': 'FACTORIAL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 864080}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2016-07', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2024-03', 'completionDateStruct': {'date': '2020-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2024-03-05', 'studyFirstSubmitDate': '2016-12-12', 'resultsFirstSubmitDate': '2021-12-24', 'studyFirstSubmitQcDate': '2016-12-19', 'lastUpdatePostDateStruct': {'date': '2024-03-08', 'type': 'ACTUAL'}, 'resultsFirstSubmitQcDate': '2024-03-05', 'studyFirstPostDateStruct': {'date': '2016-12-22', 'type': 'ESTIMATED'}, 'resultsFirstPostDateStruct': {'date': '2024-03-08', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2020-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Change in Mean Effective Dose (ED)', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the mean effective dose after the simple audit and multi-component interventions (MCI) in comparison to before the audit and multi-component interventions. The numbers given below reflect absolute change in mean dose (in millisieverts) relative to the baseline period.'}, {'measure': 'Percentage of CT Scans With an Effective Dose Above Benchmark', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the percentage of examinations with an effective dose above the benchmark after the simple audit and after multi-component intervention (MCI) in comparison to doses before the audit and MCI. The benchmark for each anatomic area is defined as the 75th percentile of the dose distribution during the pre-intervention (baseline) period.'}], 'secondaryOutcomes': [{'measure': 'Mean Dose Length Product', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the dose length product after the audit and MCI in comparison to before the audit and MCI.'}, {'measure': 'Proportion of CT Scans With a Dose Length Product Above Benchmark', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the proportion of examinations with a dose length product above the benchmark after the audit and after the MCI in comparison to doses before the audit and MCI. The benchmark for each anatomic area is defined as the 75th percentile of the dose distribution during the pre intervention period.'}, {'measure': 'Change in Mean Volume Computed Tomography Dose Index (CTDIvol)', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the mean volume CT dose index (CTDIvol) from before versus after the audit and MCI intervention. CTDIvol (in units of milligray, mGy) is a measure of radiation dose, reflecting the amount of radiation imparted per CT slice by the scanner. Higher CTDIvol signifies more radiation dose. In general, a reduction in CTDIvol would be a sign of quality improvement, minimizing excess radiation exposure to the patient.'}, {'measure': 'Percentage of CT Scans With a CTDIvol Above Benchmark', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in the percentage of examinations with a CTDIvol above the benchmark after the audit and after multicomponent intervention in comparison to doses before the audit and multicomponent intervention. The benchmark for each anatomic area is defined as the 75th percentile of the dose distribution during the pre intervention period.'}, {'measure': 'Change in Mean Organ Doses: Brain Dose for Head CT; Lung Dose For Chest CT; Colon and Liver Dose for Abdomen CT', 'timeFrame': 'Sites were randomized to 1 of 3 tracks, which determined the timing of intervention: Track A: audit at week 40, MCI at week 68 Track B: audit at week 44, MCI at week 74 Track C: audit at week 53, MCI at week 81', 'description': 'We will assess the change in organ doses after the simple audit and multi-component interventions (MCI) in comparison to before the audit and multi-component interventions. The numbers given below reflect absolute change in mean dose (in millisieverts) relative to the baseline period.'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['CT scan', 'CT exam', 'ionizing radiation', 'medical imaging', 'cat scan', 'radiation'], 'conditions': ['Ionizing Radiation Exposure', 'Quality Improvement']}, 'referencesModule': {'references': [{'pmid': '17548853', 'type': 'BACKGROUND', 'citation': 'Solberg LI. Improving medical practice: a conceptual framework. Ann Fam Med. 2007 May-Jun;5(3):251-6. doi: 10.1370/afm.666.'}, {'pmid': '18539980', 'type': 'BACKGROUND', 'citation': "Solberg LI, Asche SE, Margolis KL, Whitebird RR. Measuring an organization's ability to manage change: the change process capability questionnaire and its use for improving depression care. 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JAMA Intern Med. 2020 May 1;180(5):666-675. doi: 10.1001/jamainternmed.2020.0064.'}, {'pmid': '30602590', 'type': 'DERIVED', 'citation': 'Smith-Bindman R, Wang Y, Chu P, Chung R, Einstein AJ, Balcombe J, Cocker M, Das M, Delman BN, Flynn M, Gould R, Lee RK, Nelson TR, Schindera S, Seibert A, Starkey J, Suntharalingam S, Wetter A, Wildberger JE, Miglioretti DL. International variation in radiation dose for computed tomography examinations: prospective cohort study. BMJ. 2019 Jan 2;364:k4931. doi: 10.1136/bmj.k4931.'}], 'seeAlsoLinks': [{'url': 'http://ctdose.ucsf.edu', 'label': 'The website explores and focuses on studying the impact of medical imaging on health, minimizing the harms of medical imaging and and providing rigorous evidence to aid policymakers regarding use of medical imaging.'}]}, 'descriptionModule': {'briefSummary': 'This is a pragmatic stepped-wedge cluster randomized controlled trial to explore variation in doses used for diagnostic CT by pooling radiation dose data across diverse healthcare delivery systems.\n\nTo compare different strategies for lowering and optimizing dose and identify the barriers and facilitators to implementing successful dose optimization strategies and standardizing practice.', 'detailedDescription': 'The investigators are using a stepped-wedge cluster randomized controlled trial, collecting radiation dose information on CT from across all collaborating health care facilities, and leading several different interventions to optimize dose across facilities. In addition to collecting the CT radiation dose data, and using these results to provide feedback to the collaborating health care facilities, they will be conducting surveys of several individuals at each site, including key informants, such as lead radiologists, technologists, and medical physicist, and radiology administrators.\n\nThey will compare and identify facilitators and barriers (assessed through surveys of participating facilities) associated with successful and failed implementation of dose optimization.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'maximumAge': '99 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Diagnostic CT scans of the head, chest, and/or abdomen/pelvis performed within the study period\n\nExclusion Criteria:\n\n* non-diagnostic scans that are not of the head, chest, and/or abdomen/pelvis'}, 'identificationModule': {'nctId': 'NCT03000751', 'briefTitle': 'CT DOSE Collaboratory', 'organization': {'class': 'OTHER', 'fullName': 'University of California, San Francisco'}, 'officialTitle': 'CT Dose Optimization and Standardization Endeavor (DOSE) Collaboratory', 'orgStudyIdInfo': {'id': 'RSB-181191'}, 'secondaryIdInfos': [{'id': 'R01CA181191', 'link': 'https://reporter.nih.gov/quickSearch/R01CA181191', 'type': 'NIH'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'Track A', 'description': 'Simple Audit Report; In-Person Meeting (timed to coincide with the multi-component intervention); Multi-Component Intervention', 'interventionNames': ['Other: Simple Audit Report', 'Other: Multi-Component Intervention', 'Other: In-Person Meeting']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Track B', 'description': 'In-Person Meeting (timed to coincide with the simple audit report); Simple Audit Report; Multi-Component Intervention', 'interventionNames': ['Other: Simple Audit Report', 'Other: Multi-Component Intervention', 'Other: In-Person Meeting']}, {'type': 'OTHER', 'label': 'Track C', 'description': 'Simple Audit Report; Multi-Component Intervention', 'interventionNames': ['Other: Simple Audit Report', 'Other: Multi-Component Intervention']}], 'interventions': [{'name': 'Simple Audit Report', 'type': 'OTHER', 'description': 'The simple audit provides comparison and feedback on radiation doses.', 'armGroupLabels': ['Track A', 'Track B', 'Track C']}, {'name': 'Multi-Component Intervention', 'type': 'OTHER', 'description': 'The multi-component intervention gives tailored feedback on needed changes plus guidance using quality improvement methods that facilitate organizational change. Provides access to experts, detailed audit, collaborative calls, and site visits (as needed).', 'armGroupLabels': ['Track A', 'Track B', 'Track C']}, {'name': 'In-Person Meeting', 'type': 'OTHER', 'description': 'Collaborator meeting with an emphasis on quality improvement.', 'armGroupLabels': ['Track A', 'Track B']}]}, 'contactsLocationsModule': {'overallOfficials': [{'name': 'Rebecca Smith-Bindman, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of California, San Francisco'}, {'name': 'Judy Yee, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'San Francisco Veterans Administration'}, {'name': 'Tom Nelson, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of California, San Diego'}, {'name': 'Tony Seibert, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of California, Davis'}, {'name': 'Mayil Krishnam, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of California, Irvine'}, {'name': 'Michael Flynn, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Henry Ford Health System'}, {'name': 'Mary Cocker, MSc, Csci', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Oxford University Hospitals NHS Trust'}, {'name': 'William Boswell, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'City of Hope Medical Center'}, {'name': 'Sebastian Schindera, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University Hospital of Basel'}, {'name': 'Erin Bell, MHP', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Community Health Network'}, {'name': 'Phuong-Anh Duong, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Emory University'}, {'name': 'Nima Kasraie, PhD, MSc', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': "Children's Mercy Hospital Kansas City"}, {'name': 'Pavlina Pike, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Huntsville Hospital'}, {'name': 'Luisa Cervantes, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': "Nicklaus Children's Hospital f/k/a Miami Children's Hospital"}, {'name': 'Joachim Wildberger, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Maastricht University Medical Center'}, {'name': 'Michael Forsting, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of Duisburg-Essen'}, {'name': 'Fady Kassem, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'St. Joseph Hospital of Orange'}, {'name': 'Darrell Fendrick, CT', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'East Texas Medical Center'}, {'name': 'Sugoto Mukherjee, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of Virginia Health System'}, {'name': 'Brad Delman, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Icahn School of Medicine at Mount Sinai'}, {'name': 'Jodi Roehm', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Center for Diagnostic Imaging'}, {'name': 'Anokh Pahwa, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Olive View - UCLA'}, {'name': 'Ryan Lee, MD, MBA', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Einstein Medical Center'}, {'name': 'Jay Starkey, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': "St. Luke's International Hospital, Tokyo"}, {'name': 'Diana Miglioretti, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of California, Davis'}, {'name': 'Saravanabavaan Suntharalingam, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of Duisburg-Essen'}, {'name': 'Sara Lewis, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Icahn School of Medicine at Mount Sinai'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of California, San Francisco', 'class': 'OTHER'}, 'collaborators': [{'name': 'University of California, Davis', 'class': 'OTHER'}, {'name': 'University Hospital, Basel, Switzerland', 'class': 'OTHER'}, {'name': 'Center for Diagnostic Imaging', 'class': 'OTHER'}, {'name': 'Community Health Network', 'class': 'OTHER'}, {'name': "Children's Mercy Hospital Kansas City", 'class': 'OTHER'}, {'name': 'City of Hope Medical Center', 'class': 'OTHER'}, {'name': 'Albert Einstein Healthcare Network', 'class': 'OTHER'}, {'name': 'Universität Duisburg-Essen', 'class': 'OTHER'}, {'name': 'East Texas Medical Center Regional Healthcare System', 'class': 'OTHER'}, {'name': 'Emory University', 'class': 'OTHER'}, {'name': 'Henry Ford Health System', 'class': 'OTHER'}, {'name': 'Huntsville Hospital Health System', 'class': 'OTHER'}, {'name': "Nicklaus Children's Hospital f/k/a Miami Children's Hospital", 'class': 'OTHER'}, {'name': 'Mount Sinai Hospital, New York', 'class': 'OTHER'}, {'name': 'Maastricht University Medical Center', 'class': 'OTHER'}, {'name': 'Olive View-UCLA Education & Research Institute', 'class': 'OTHER'}, {'name': 'Oxford University Hospitals NHS Trust', 'class': 'OTHER'}, {'name': 'San Francisco VA Health Care System', 'class': 'FED'}, {'name': 'St. Joseph Hospital of Orange', 'class': 'OTHER'}, {'name': "St. Luke's International Hospital, Japan", 'class': 'OTHER'}, {'name': 'University of Virginia', 'class': 'OTHER'}, {'name': 'University of California, Irvine', 'class': 'OTHER'}, {'name': 'University of California, San Diego', 'class': 'OTHER'}, {'name': 'National Cancer Institute (NCI)', 'class': 'NIH'}], 'responsibleParty': {'type': 'SPONSOR'}}}}