Ignite Creation Date:
2025-12-24 @ 11:40 PM
Ignite Modification Date:
2025-12-25 @ 9:31 PM
Study NCT ID:
NCT04455451
Status:
COMPLETED
Last Update Posted:
2022-01-12
First Post:
2020-07-01
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Intensive Care Therapy of Covid-19 Disease in Germany
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'OTHER', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 2054}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2020-08-06', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-09', 'completionDateStruct': {'date': '2021-09-30', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2022-01-11', 'studyFirstSubmitDate': '2020-07-01', 'studyFirstSubmitQcDate': '2020-07-01', 'lastUpdatePostDateStruct': {'date': '2022-01-12', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2020-07-02', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2021-08-15', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Mortality', 'timeFrame': 'up to 150 days', 'description': 'ICU Mortality of patients'}], 'secondaryOutcomes': [{'measure': 'ICU length of stay', 'timeFrame': 'up to 150 days', 'description': 'Intensive care unit length of stay'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['COVID', 'ARDS']}, 'referencesModule': {'references': [{'pmid': '34404458', 'type': 'DERIVED', 'citation': 'Magunia H, Lederer S, Verbuecheln R, Gilot BJ, Koeppen M, Haeberle HA, Mirakaj V, Hofmann P, Marx G, Bickenbach J, Nohe B, Lay M, Spies C, Edel A, Schiefenhovel F, Rahmel T, Putensen C, Sellmann T, Koch T, Brandenburger T, Kindgen-Milles D, Brenner T, Berger M, Zacharowski K, Adam E, Posch M, Moerer O, Scheer CS, Sedding D, Weigand MA, Fichtner F, Nau C, Pratsch F, Wiesmann T, Koch C, Schneider G, Lahmer T, Straub A, Meiser A, Weiss M, Jungwirth B, Wappler F, Meybohm P, Herrmann J, Malek N, Kohlbacher O, Biergans S, Rosenberger P. Machine learning identifies ICU outcome predictors in a multicenter COVID-19 cohort. Crit Care. 2021 Aug 17;25(1):295. doi: 10.1186/s13054-021-03720-4.'}], 'seeAlsoLinks': [{'url': 'https://www.medizin.uni-tuebingen.de/de/covid-intensivstudie', 'label': 'Study Landing Page'}]}, 'descriptionModule': {'briefSummary': 'Multi-center retrospective and prospective observational study of Covid-19 patients with severe or critical illness treated on a German ICU'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Adults admitted for ICU therapy due to severe or critical Covid-19', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age above 18 years\n* Covid-19 disease (positive SARS-CoV-2 PCR)\n\nExclusion Criteria:\n\n-none'}, 'identificationModule': {'nctId': 'NCT04455451', 'briefTitle': 'Intensive Care Therapy of Covid-19 Disease in Germany', 'organization': {'class': 'OTHER', 'fullName': 'University Hospital Tuebingen'}, 'officialTitle': 'Intensive Care Therapy of Covid-19 Disease in Germany an Multi-center Observational Study', 'orgStudyIdInfo': {'id': 'DCIR'}}, 'contactsLocationsModule': {'locations': [{'city': 'Aachen', 'country': 'Germany', 'facility': 'RWTH Aachen - Department for operative Intensive Care Medicine and intermediate Care', 'geoPoint': {'lat': 50.77664, 'lon': 6.08342}}, {'city': 'Balingen', 'country': 'Germany', 'facility': 'Zollernalbklinikum', 'geoPoint': {'lat': 48.27525, 'lon': 8.85464}}, {'city': 'Berlin', 'country': 'Germany', 'facility': 'Charité Universitätsmedizin Berlin', 'geoPoint': {'lat': 52.52437, 'lon': 13.41053}}, {'city': 'Bochum', 'country': 'Germany', 'facility': 'UH Bochum - Department for Anesthesiology and Intensive Care Medicine', 'geoPoint': {'lat': 51.48165, 'lon': 7.21648}}, {'city': 'Bonn', 'country': 'Germany', 'facility': 'Universitätsklinikum Bonn', 'geoPoint': {'lat': 50.73438, 'lon': 7.09549}}, {'city': 'Cologne', 'country': 'Germany', 'facility': 'Klinikum der Universität Witten/Herdecke - Köln / Klinik für Anästhesiologie und operative Intensivmedizin', 'geoPoint': {'lat': 50.93333, 'lon': 6.95}}, {'city': 'Dresden', 'country': 'Germany', 'facility': 'Universitätsklinikum Carl Gustav Carus Dresden', 'geoPoint': {'lat': 51.05089, 'lon': 13.73832}}, {'city': 'Duisburg', 'country': 'Germany', 'facility': 'Ev. Krankenhaus Bethesda Duisburg Klinik für Anästhesiologie und Intensivmedizin', 'geoPoint': {'lat': 51.43247, 'lon': 6.76516}}, {'city': 'Düsseldorf', 'country': 'Germany', 'facility': 'Univerrsitätsklinikum Düsseldorf', 'geoPoint': {'lat': 51.22172, 'lon': 6.77616}}, {'city': 'Essen', 'country': 'Germany', 'facility': 'Universitätsklinikum Essen', 'geoPoint': {'lat': 51.45657, 'lon': 7.01228}}, {'city': 'Frankfurt', 'country': 'Germany', 'facility': 'Universitätsklinikum Frankfurt', 'geoPoint': {'lat': 49.68333, 'lon': 10.53333}}, {'city': 'Freiburg im Breisgau', 'country': 'Germany', 'facility': 'University Hospital Freiburg - Department for Anesthesiology and Intensive Care Medicine', 'geoPoint': {'lat': 47.9959, 'lon': 7.85222}}, {'city': 'Giessen', 'country': 'Germany', 'facility': 'Universitätsklinikum Giessen Klinik für Anaesthesiologie und operative Intensivmedizin', 'geoPoint': {'lat': 50.58727, 'lon': 8.67554}}, {'city': 'Göttingen', 'country': 'Germany', 'facility': 'Universitätsmedizin Göttingen Klinik für Anästhesiologie', 'geoPoint': {'lat': 51.53443, 'lon': 9.93228}}, {'city': 'Greifswald', 'country': 'Germany', 'facility': 'Universitätsklinikum Greifswald', 'geoPoint': {'lat': 54.08905, 'lon': 13.40244}}, {'city': 'Halle', 'country': 'Germany', 'facility': 'Universitätsklinikum Halle', 'geoPoint': {'lat': 51.48158, 'lon': 11.97947}}, {'city': 'Heidelberg', 'country': 'Germany', 'facility': 'University Hospital Heidelberg - Department for Anesthesiologie and Intensive Care Medicine', 'geoPoint': {'lat': 49.40768, 'lon': 8.69079}}, {'city': 'Homburg/Saar', 'country': 'Germany', 'facility': 'Universitätsklinikum des Saarlandes'}, {'city': 'Leipzig', 'country': 'Germany', 'facility': 'Universitätsklinikum Leipzig', 'geoPoint': {'lat': 51.33962, 'lon': 12.37129}}, {'city': 'Lübeck', 'country': 'Germany', 'facility': 'UKSH Campus Lübeck - Department for Anesthesiology and Intensive Care Medicine', 'geoPoint': {'lat': 53.86893, 'lon': 10.68729}}, {'city': 'Magdeburg', 'country': 'Germany', 'facility': 'University Hospital Magdeburg - Department for Anesthesiology and Intensive Care Medicine', 'geoPoint': {'lat': 52.13129, 'lon': 11.63189}}, {'city': 'Marburg', 'country': 'Germany', 'facility': 'Universitätsklinikum Marburg', 'geoPoint': {'lat': 50.80904, 'lon': 8.77069}}, {'city': 'München', 'country': 'Germany', 'facility': 'Technische Universität München', 'geoPoint': {'lat': 51.60698, 'lon': 13.31243}}, {'city': 'Ravensburg', 'country': 'Germany', 'facility': 'Oberschwabenklinik Ravensburg Klinik für Anästhesie-, Intensiv-, Notfall- und Schmerzmedizin', 'geoPoint': {'lat': 47.78198, 'lon': 9.61062}}, {'city': 'Tübingen', 'country': 'Germany', 'facility': 'University Hospital Tübingen - Department for Anesthesiology and Intensive Care Medicine', 'geoPoint': {'lat': 48.52266, 'lon': 9.05222}}, {'city': 'Ulm', 'country': 'Germany', 'facility': 'Universitätsklinikum Ulm', 'geoPoint': {'lat': 48.39841, 'lon': 9.99155}}, {'city': 'Würzburg', 'country': 'Germany', 'facility': 'Universitätsklinikum Würzburg Klinik und Poliklinik für Anästhesiologie, Intensivmedizin und Schmerztherapie', 'geoPoint': {'lat': 49.79391, 'lon': 9.95121}}], 'overallOfficials': [{'name': 'Peter Rosenberger, MD, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University Hospital Tübingen'}, {'name': 'Harry Magunia, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University Hospital Tübingen'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital Tuebingen', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}