Ignite Creation Date:
2025-12-26 @ 5:24 PM
Ignite Modification Date:
2025-12-26 @ 5:24 PM
Study NCT ID:
NCT04345406
Status:
NOT_YET_RECRUITING
Last Update Posted:
2020-04-14
First Post:
2020-04-11
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Angiotensin Converting Enzyme Inhibitors in Treatment of Covid 19
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D004656', 'term': 'Enalapril'}, {'id': 'D002216', 'term': 'Captopril'}, {'id': 'D002738', 'term': 'Chloroquine'}], 'ancestors': [{'id': 'D004151', 'term': 'Dipeptides'}, {'id': 'D009842', 'term': 'Oligopeptides'}, {'id': 'D010455', 'term': 'Peptides'}, {'id': 'D000602', 'term': 'Amino Acids, Peptides, and Proteins'}, {'id': 'D011392', 'term': 'Proline'}, {'id': 'D007098', 'term': 'Imino Acids'}, {'id': 'D000598', 'term': 'Amino Acids, Cyclic'}, {'id': 'D000596', 'term': 'Amino Acids'}, {'id': 'D000634', 'term': 'Aminoquinolines'}, {'id': 'D011804', 'term': 'Quinolines'}, {'id': 'D006574', 'term': 'Heterocyclic Compounds, 2-Ring'}, {'id': 'D000072471', 'term': 'Heterocyclic Compounds, Fused-Ring'}, {'id': 'D006571', 'term': 'Heterocyclic Compounds'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 60}}, 'statusModule': {'overallStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2020-04-15', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2020-04', 'completionDateStruct': {'date': '2029-12-01', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2020-04-11', 'studyFirstSubmitDate': '2020-04-11', 'studyFirstSubmitQcDate': '2020-04-11', 'lastUpdatePostDateStruct': {'date': '2020-04-14', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2020-04-14', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2029-12-01', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'number of patients with virological cure', 'timeFrame': '6 months', 'description': 'number of patients with virological cure'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['COVID']}, 'descriptionModule': {'briefSummary': 'ACEIs as treatment for COVID19', 'detailedDescription': 'ACEIs as suggested treatment for COVID19'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Patients infected with covid 19\n\nExclusion Criteria:\n\n* allergy or contraindications to the drug'}, 'identificationModule': {'nctId': 'NCT04345406', 'briefTitle': 'Angiotensin Converting Enzyme Inhibitors in Treatment of Covid 19', 'organization': {'class': 'OTHER', 'fullName': 'Tanta University'}, 'officialTitle': 'Randomized Trial of ACEIs in Treatment of COVID-19', 'orgStudyIdInfo': {'id': 'ACEIS COVID 19'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'ACEIs', 'description': 'ACEIs with conventional treatment for COVID19', 'interventionNames': ['Drug: ACEIs', 'Drug: Conventional treatment']}, {'type': 'EXPERIMENTAL', 'label': 'Conventional treatment of COVID19', 'description': 'Conventional treatment of COVID19', 'interventionNames': ['Drug: Conventional treatment']}], 'interventions': [{'name': 'ACEIs', 'type': 'DRUG', 'otherNames': ['Enalapril, Captopril'], 'description': 'Captopril or enalapril', 'armGroupLabels': ['ACEIs']}, {'name': 'Conventional treatment', 'type': 'DRUG', 'otherNames': ['chloroquine'], 'description': 'alexoquine', 'armGroupLabels': ['ACEIs', 'Conventional treatment of COVID19']}]}, 'contactsLocationsModule': {'locations': [{'zip': '35111', 'city': 'Tanta', 'country': 'Egypt', 'facility': 'Tanta University', 'geoPoint': {'lat': 30.78847, 'lon': 31.00192}}], 'centralContacts': [{'name': 'Sherief Abd-Elsalam', 'role': 'CONTACT', 'email': 'sheriefabdelsalam@yahoo.com', 'phone': '+201147773440'}], 'overallOfficials': [{'name': 'Sherief Abd-Elsalam, ass. prof.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Tanta University Faculty of medicine'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Tanta University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'assistant professor of tropical medicine and infectious diseases', 'investigatorFullName': 'Sherief Abd-Elsalam', 'investigatorAffiliation': 'Tanta University'}}}}