Ignite Creation Date:
2025-12-26 @ 4:01 PM
Ignite Modification Date:
2026-02-24 @ 8:48 AM
Study NCT ID:
NCT00718406
Status:
COMPLETED
Last Update Posted:
2008-07-18
First Post:
2008-07-16
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D054058', 'term': 'Acute Coronary Syndrome'}, {'id': 'D002637', 'term': 'Chest Pain'}], 'ancestors': [{'id': 'D017202', 'term': 'Myocardial Ischemia'}, {'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D010146', 'term': 'Pain'}, {'id': 'D009461', 'term': 'Neurologic Manifestations'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D008790', 'term': 'Metoprolol'}, {'id': 'D009020', 'term': 'Morphine'}], 'ancestors': [{'id': 'D050198', 'term': 'Phenoxypropanolamines'}, {'id': 'D011412', 'term': 'Propanolamines'}, {'id': 'D000605', 'term': 'Amino Alcohols'}, {'id': 'D000438', 'term': 'Alcohols'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D020005', 'term': 'Propanols'}, {'id': 'D000588', 'term': 'Amines'}, {'id': 'D009022', 'term': 'Morphine Derivatives'}, {'id': 'D009019', 'term': 'Morphinans'}, {'id': 'D053610', 'term': 'Opiate Alkaloids'}, {'id': 'D000470', 'term': 'Alkaloids'}, {'id': 'D006571', 'term': 'Heterocyclic Compounds'}, {'id': 'D006572', 'term': 'Heterocyclic Compounds, Bridged-Ring'}, {'id': 'D006576', 'term': 'Heterocyclic Compounds, 4 or More Rings'}, {'id': 'D000072471', 'term': 'Heterocyclic Compounds, Fused-Ring'}, {'id': 'D010616', 'term': 'Phenanthrenes'}, {'id': 'D011084', 'term': 'Polycyclic Aromatic Hydrocarbons'}, {'id': 'D011083', 'term': 'Polycyclic Compounds'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE4'], 'studyType': 'INTERVENTIONAL'}, 'statusModule': {'overallStatus': 'COMPLETED', 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2002-08', 'lastUpdateSubmitDate': '2008-07-16', 'studyFirstSubmitDate': '2008-07-16', 'studyFirstSubmitQcDate': '2008-07-16', 'lastUpdatePostDateStruct': {'date': '2008-07-18', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2008-07-18', 'type': 'ESTIMATED'}}, 'conditionsModule': {'keywords': ['Acute coronary syndrome', 'Chest pain', 'Betablockers', 'Morphine', 'Prehospital phase'], 'conditions': ['Acute Coronary Syndromes']}, 'descriptionModule': {'briefSummary': 'The primary aim was to evaluate the relief of chest pain during the first 30 minutes among patients who received metoprolol alone as compared with metoprolol plus morphine'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Acute chest pain\n* ECG-signs indicating myocardial ischemia\n\nExclusion Criteria:\n\n* Heart rate \\< 60 beats/min\n* Systolic blood pressure \\< 110 mmHg\n* High degree AV-block\n* Signs of obstructive pulmonary disease\n* Signs of pulmonary oedema\n* Unwillingness\n* Participation in other studies\n* Long delay between arrival of ambulance and randomisation'}, 'identificationModule': {'nctId': 'NCT00718406', 'briefTitle': 'Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain', 'organization': {'class': 'OTHER', 'fullName': 'Sahlgrenska University Hospital'}, 'orgStudyIdInfo': {'id': 'S203-02'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'A', 'description': 'A=metoprolol', 'interventionNames': ['Drug: Metoprolol']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'B', 'description': 'B=metoprolol plus morphine', 'interventionNames': ['Drug: metoprolol plus morphine']}], 'interventions': [{'name': 'Metoprolol', 'type': 'DRUG', 'armGroupLabels': ['A']}, {'name': 'metoprolol plus morphine', 'type': 'DRUG', 'armGroupLabels': ['B']}]}, 'contactsLocationsModule': {'locations': [{'zip': 'SE-413 45', 'city': 'Gothenburg', 'country': 'Sweden', 'facility': 'Medical Institution, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital', 'geoPoint': {'lat': 57.70716, 'lon': 11.96679}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Sahlgrenska University Hospital', 'class': 'OTHER'}, 'collaborators': [{'name': 'AstraZeneca', 'class': 'INDUSTRY'}]}}}