Ignite Creation Date:
2025-12-26 @ 3:59 PM
Ignite Modification Date:
2025-12-29 @ 6:38 AM
Study NCT ID:
NCT00789906
Status:
UNKNOWN
Last Update Posted:
2008-11-13
First Post:
2008-11-11
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D012559', 'term': 'Schizophrenia'}], 'ancestors': [{'id': 'D019967', 'term': 'Schizophrenia Spectrum and Other Psychotic Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 700}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2008-07'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2008-11', 'lastUpdateSubmitDate': '2008-11-12', 'studyFirstSubmitDate': '2008-11-11', 'studyFirstSubmitQcDate': '2008-11-12', 'lastUpdatePostDateStruct': {'date': '2008-11-13', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2008-11-13', 'type': 'ESTIMATED'}}, 'conditionsModule': {'keywords': ['Computerized Neuropsychological Assessment', 'Development of Population Norms of the Computerized Neuropsychological Assessment'], 'conditions': ['Schizophrenia']}, 'descriptionModule': {'briefSummary': 'Schizophrenia affects cognition, emotion, and behavior. Neuropsychological assessment enables a better understanding of antipsychotic effectiveness and the brain processes, underlying cognitive functioning in schizophrenia.\n\nNeurocognitive deficits in schizophrenia patients appears to explain up to 61% of the variance of functional outcome and is an important predictor of social reintegration (Peuskens et al, 2005) and independent living activitiy (Green et al, 2004). Impaired social functioning within schizophrenia population has been associated with increased health-care costs. Since social and occupational disability may generate the largest indirect costs of the illness, treatment of cognitive deficits has an enormous impact on the cost and disability associated with schizophrenia (McGurk and Mueser, 2004).\n\nHowever, the gap between cognitive science and clinical practice limits the implementation of cognitive assessment in the routine evaluation of schizophrenia patients. Pharmaceutical industry initiated numerous large scale, multisite studies on the impact of novel antipsychotics on cognitive deficits in schizophrenia patients.\n\nThe aim of this research is to develop population norms of the computerized neuropsychological assessment for effectiveness of the antipsychotic treatment in schizophrenia.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '89 Years', 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': '700 healthy adults (350 women and 350 men, aged from 18 to 89)', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* An IQ, which is within normal range.\n\nExclusion Criteria:\n\n* Psychiatric co-morbidity.\n* Physical disability or illness.\n* A history of severe head injury.'}, 'identificationModule': {'nctId': 'NCT00789906', 'briefTitle': 'Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia', 'organization': {'class': 'OTHER_GOV', 'fullName': 'BeerYaakov Mental Health Center'}, 'officialTitle': 'Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia', 'orgStudyIdInfo': {'id': '223CTIL'}}, 'armsInterventionsModule': {'armGroups': [{'label': '1', 'description': '350 healthy women , aged from 18 to 89'}, {'label': '2', 'description': '350 healthy men, aged from 18 to 89'}]}, 'contactsLocationsModule': {'locations': [{'zip': '70350', 'city': 'Beer Yaacov', 'status': 'RECRUITING', 'country': 'Israel', 'contacts': [{'name': 'Kertzman', 'role': 'CONTACT', 'email': 'research@beerness.health.gov.il', 'phone': '972-8-9776136'}, {'name': 'Semion Kertzman, M.D.', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Beer-Yaacov MHC'}], 'centralContacts': [{'name': 'Semyon Kertzman, MD', 'role': 'CONTACT', 'email': 'research@beerness.health.gov.il', 'phone': '972-8-9776136'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'BeerYaakov Mental Health Center', 'class': 'OTHER_GOV'}, 'responsibleParty': {'oldNameTitle': 'Semion Kertzman', 'oldOrganization': 'BeerYaakov Mental Health Center'}}}}