Ignite Creation Date:
2025-12-24 @ 1:39 PM
Ignite Modification Date:
2026-02-24 @ 2:31 PM
Study NCT ID:
NCT02116595
Status:
WITHDRAWN
Last Update Posted:
2017-07-27
First Post:
2014-04-15
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Urine pH and Diet Net Acid Load
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'DIAGNOSTIC', 'interventionModel': 'CROSSOVER'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 0}}, 'statusModule': {'whyStopped': 'not funded', 'overallStatus': 'WITHDRAWN', 'startDateStruct': {'date': '2015-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2017-07', 'completionDateStruct': {'date': '2016-05', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2017-07-25', 'studyFirstSubmitDate': '2014-04-15', 'studyFirstSubmitQcDate': '2014-04-16', 'lastUpdatePostDateStruct': {'date': '2017-07-27', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2014-04-17', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2015-06', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'high acid diet', 'timeFrame': '6 months', 'description': 'correlation between first morning urine pH and 24 hour net acid excretion'}, {'measure': 'low acid diet', 'timeFrame': '6 months', 'description': 'correlation between first morning urine pH and 24 hour net acid excretion'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['volunteers'], 'conditions': ['Healthy']}, 'descriptionModule': {'briefSummary': 'Presently, the gold standard for testing diet acid intake is a urine collection done for many hours, usually 24 hours, which must be analyzed in a research lab for "net acid excretion". So, getting information about diet acid intake is difficult. Many people have suggested doing a much simpler test, which is checking the pH of the urine when you wake up. But, no one has studied if this simpler method is a valid method for estimating the 24 hour net acid excretion. Diet acid load may be important in many diseases associated with aging, such as loss of bone and muscle, and the development of kidney disease.', 'detailedDescription': 'the primary outcome variable is morning urine pH and 24 hour urine net acid excretion'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* no medical or psychological problems\n* able to come to UCSF for study\n\nExclusion Criteria:\n\n* pregnant or trying to become pregnant\n* Hg \\< 10\n* abnormal screening labs\n* anyone unable to follow study directions'}, 'identificationModule': {'nctId': 'NCT02116595', 'briefTitle': 'Urine pH and Diet Net Acid Load', 'organization': {'class': 'OTHER', 'fullName': 'University of California, San Francisco'}, 'officialTitle': 'Alterations in Urine pH With Differing Diet Net Acid Loads', 'orgStudyIdInfo': {'id': 'UPH&DNAE'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'feeding a high acid diet x 24 hrs', 'description': '2 diets, one low and one high net acid loads', 'interventionNames': ['Other: high or low acid diet']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'low acid diet', 'interventionNames': ['Other: high or low acid diet']}], 'interventions': [{'name': 'high or low acid diet', 'type': 'OTHER', 'description': 'high or low acid diets', 'armGroupLabels': ['feeding a high acid diet x 24 hrs', 'low acid diet']}]}, 'contactsLocationsModule': {'locations': [{'zip': '94143', 'city': 'San Francisco', 'state': 'California', 'country': 'United States', 'facility': 'UCSF', 'geoPoint': {'lat': 37.77493, 'lon': -122.41942}}], 'overallOfficials': [{'name': 'lynda frassetto, md', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University of California, San Francisco'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of California, San Francisco', 'class': 'OTHER'}, 'collaborators': [{'name': 'optimal wellness labs', 'class': 'UNKNOWN'}], 'responsibleParty': {'type': 'SPONSOR'}}}}