Ignite Creation Date:
2025-12-24 @ 11:32 PM
Ignite Modification Date:
2026-01-06 @ 2:46 AM
Study NCT ID:
NCT03217656
Status:
RECRUITING
Last Update Posted:
2018-01-23
First Post:
2017-06-18
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Jiaxing Birth Cohort in China
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D063766', 'term': 'Pediatric Obesity'}, {'id': 'D000740', 'term': 'Anemia'}, {'id': 'D011248', 'term': 'Pregnancy Complications'}, {'id': 'D046110', 'term': 'Hypertension, Pregnancy-Induced'}, {'id': 'D005247', 'term': 'Feeding Behavior'}], 'ancestors': [{'id': 'D009765', 'term': 'Obesity'}, {'id': 'D050177', 'term': 'Overweight'}, {'id': 'D044343', 'term': 'Overnutrition'}, {'id': 'D009748', 'term': 'Nutrition Disorders'}, {'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}, {'id': 'D001835', 'term': 'Body Weight'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D006402', 'term': 'Hematologic Diseases'}, {'id': 'D006425', 'term': 'Hemic and Lymphatic Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D006973', 'term': 'Hypertension'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D001522', 'term': 'Behavior, Animal'}, {'id': 'D001519', 'term': 'Behavior'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 500000}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '1999-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2018-01', 'completionDateStruct': {'date': '2029-01', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2018-01-18', 'studyFirstSubmitDate': '2017-06-18', 'studyFirstSubmitQcDate': '2017-07-11', 'lastUpdatePostDateStruct': {'date': '2018-01-23', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2017-07-14', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2019-01', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'overweight and obesity', 'timeFrame': 'Up to 6-7 years old for these children', 'description': 'BMI-z-score was calculated from height and weight. BMI-z-score\\>1 was defined as overweight/obesity'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Childhood Obesity', 'Anemia', 'Pregnancy Complications', 'Pregnancy; Hypertension', 'Feeding Behavior']}, 'referencesModule': {'references': [{'pmid': '27940484', 'type': 'BACKGROUND', 'citation': 'Zheng JS, Liu H, Jiang J, Huang T, Wang F, Guan Y, Li D. Cohort Profile: The Jiaxing Birth Cohort in China. Int J Epidemiol. 2017 Oct 1;46(5):1382-1382g. doi: 10.1093/ije/dyw203. No abstract available.'}]}, 'descriptionModule': {'briefSummary': 'The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child pairs were recruited in Jiaxing area in south-east China.Children of the recruited women were followed up at 1-2, 3, 6, 9 and 12 months of age, and subsequently followed up every 6 months to 36 months of age (toddler stage), and every year to 6-7 years of age before they went to school (pre-school stage). Follow-up rate was 70.8% at the toddler stage and 68.9% at the pre-school stage up to June 2013.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Between 1999 and 2013, 363 416 pregnancies were followed from initial registration to the end of the pregnancy, with 25 003 children born to the above women having no further information (registration) after the birth. Therefore, a total of 338 413 live mother-child pairs registered at local clinics, and were enrolled in the Jiaxing Birth Cohort.\n\nAmong the 338 413 children, there were 332 532 singletons, 2883 pairs of twins (n = 5766), 37 pairs of triplets (n= 111), and 1 pair of quadruplets (n = 4).', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Pregnant women came to clinic visit at one of the local hospitals during pregnancy at Jiaxing area\n2. Pregnant women were followed up during pregnancy and their children were born alive at local hospital or clinics\n\nExclusion Criteria:\n\n1. Those who did not want to participant\n2. The infant was dead at the birth\n3. Those pregnant mothers who dropped out during follow-up at pregnancy or moved out of the Jiaxing area'}, 'identificationModule': {'nctId': 'NCT03217656', 'acronym': 'JBC', 'briefTitle': 'The Jiaxing Birth Cohort in China', 'organization': {'class': 'OTHER', 'fullName': 'Zhejiang University'}, 'officialTitle': 'The Jiaxing Birth Cohort in China', 'orgStudyIdInfo': {'id': 'ZJU_JBC2013013'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Mother-child birth cohort', 'interventionNames': ['Other: No intervention']}], 'interventions': [{'name': 'No intervention', 'type': 'OTHER', 'armGroupLabels': ['Mother-child birth cohort']}]}, 'contactsLocationsModule': {'locations': [{'zip': '310058', 'city': 'Hangzhou', 'state': 'Zhejiang', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Duo Li, Ph.D.', 'role': 'CONTACT', 'email': 'duoli@zju.edu.cn', 'phone': '+86 571 88982024'}, {'name': 'Duo Li, PhD', 'role': 'PRINCIPAL_INVESTIGATOR'}, {'name': 'Ju-Sheng Zheng, PhD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Zhejiang University', 'geoPoint': {'lat': 30.29365, 'lon': 120.16142}}], 'centralContacts': [{'name': 'Duo Li, PhD', 'role': 'CONTACT', 'email': 'duoli@zju.edu.cn'}, {'name': 'Ju-Sheng Zheng, PhD', 'role': 'CONTACT', 'email': 'zhengjusheng@wias.org.cn'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Zhejiang University', 'class': 'OTHER'}, 'collaborators': [{'name': 'Jiaxing Maternity and Child Health Care Hospital', 'class': 'OTHER'}, {'name': 'Qingdao University', 'class': 'OTHER'}, {'name': 'Westlake University', 'class': 'OTHER'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Duo li', 'investigatorAffiliation': 'Zhejiang University'}}}}