Ignite Creation Date:
2025-12-24 @ 11:30 PM
Ignite Modification Date:
2026-01-03 @ 6:48 PM
Study NCT ID:
NCT02449356
Status:
COMPLETED
Last Update Posted:
2017-06-15
First Post:
2015-04-26
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'zwyfeng@163.com', 'phone': '+8684327413', 'title': 'Jiali Shao', 'organization': 'Xiangya Hospital'}, 'certainAgreement': {'piSponsorEmployee': True}, 'limitationsAndCaveats': {'description': 'No limitations and caveats.'}}, 'adverseEventsModule': {'timeFrame': 'within the postoperative 24 hours', 'description': 'the incidence rate of sore throat, hoarseness, dysphagia in both groups at 24-hour follow-up has been collected and calculated.', 'eventGroups': [{'id': 'EG000', 'title': 'Prone Position Endotracheal Tube', 'description': 'there was one patient in this group occuring mild sore throat,and none occured dysphagia, dysphonia.', 'otherNumAtRisk': 30, 'otherNumAffected': 1, 'seriousNumAtRisk': 30, 'seriousNumAffected': 0}, {'id': 'EG001', 'title': 'Traditional Endotracheal Tube', 'description': 'there was one patient in this group occuring mild sore throat,and none occured dysphagia, dysphonia.', 'otherNumAtRisk': 30, 'otherNumAffected': 1, 'seriousNumAtRisk': 30, 'seriousNumAffected': 0}], 'otherEvents': [{'term': 'Sore throat', 'notes': 'after the extubation of endotracheal tube, we investigated the participates whether they occured the sore throat, and the severity.', 'stats': [{'groupId': 'EG000', 'numAtRisk': 30, 'numEvents': 1, 'numAffected': 1}, {'groupId': 'EG001', 'numAtRisk': 30, 'numEvents': 1, 'numAffected': 1}], 'organSystem': 'Skin and subcutaneous tissue disorders', 'assessmentType': 'NON_SYSTEMATIC_ASSESSMENT'}], 'frequencyThreshold': '0'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Displacement of the Endotracheal Tube', 'denoms': [{'units': 'Participants', 'counts': [{'value': '30', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Prone Ventilation Endotracheal Tube', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.\n\nprone ventilation endotracheal tube: some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes'}, {'id': 'OG001', 'title': 'the Traditional Endotracheal Tube', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}], 'classes': [{'title': 'The overall incidence of displacement', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '22', 'groupId': 'OG001'}]}]}, {'title': 'Mild displacement', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '11', 'groupId': 'OG001'}]}]}, {'title': 'Moderate displacement', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '8', 'groupId': 'OG001'}]}]}, {'title': 'Severe displacement', 'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '3', 'groupId': 'OG001'}]}]}], 'analyses': [{'pValue': '<0.05', 'groupIds': ['OG000', 'OG001'], 'paramType': 'Odds Ratio (OR)', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '0.73', 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER'}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'Participants were followed for the duration of surgery, an average of 2 hours.', 'description': 'We divided the degree of the displacement of the endotracheal tube into 3 kinds, which included mild(displacement distance\\<0.5cm),moderate(0.5cm≤displacement distance\\<1.5cm),severe (1.5cm≤displacement distance).', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'All patients in each group were analyzed'}, {'type': 'SECONDARY', 'title': 'The Number of the Prolapse of Endotracheal Tube', 'denoms': [{'units': 'Participants', 'counts': [{'value': '30', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Prone Ventilation Endotracheal Tube', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.\n\nprone ventilation endotracheal tube: some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes'}, {'id': 'OG001', 'title': 'the Traditional Endotracheal Tube', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}], 'classes': [{'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}], 'analyses': [{'pValue': '>0.05', 'groupIds': ['OG000', 'OG001'], 'statisticalMethod': 'Chi-squared', 'nonInferiorityType': 'SUPERIORITY_OR_OTHER'}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'At any time within the procedure of the whole surgery', 'description': 'Counting the number who occured the prolapse of endotracheal tube in both groups', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'All participants in both groups were analyzed'}, {'type': 'SECONDARY', 'title': 'the Degree of Loose or Dampness of the Tape', 'denoms': [{'units': 'Participants', 'counts': [{'value': '30', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'the Traditional Endotracheal Tube', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}, {'id': 'OG001', 'title': 'Prone Ventilation Endotracheal Tube', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.\n\nprone ventilation endotracheal tube: some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes'}], 'classes': [{'categories': [{'measurements': [{'value': '7', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'at the time when patients were turning to supine position', 'description': 'counting and quantifying the number who occured the dampness or loose of the tape in both groups', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'all participants in both groups were analyzed'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'the Incidence of Dysphagia', 'denoms': [{'units': 'Participants', 'counts': [{'value': '30', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'the Traditional Endotracheal Tube', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}, {'id': 'OG001', 'title': 'Prone Ventilation Endotracheal Tube', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.\n\nprone ventilation endotracheal tube: some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes'}], 'classes': [{'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'within the first 24 hours after extubation', 'description': 'count the number who suffered the dysphagia within the first 24 hours after extubation', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'all patients were analyzed'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'the Incidence of Sore Throat', 'denoms': [{'units': 'Participants', 'counts': [{'value': '30', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'the Traditional Endotracheal Tube', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}, {'id': 'OG001', 'title': 'Prone Ventilation Endotracheal Tube', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.\n\nprone ventilation endotracheal tube: some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes'}], 'classes': [{'categories': [{'measurements': [{'value': '1', 'groupId': 'OG000'}, {'value': '1', 'groupId': 'OG001'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'within the first 24 hour after extubation', 'description': 'count the number who suffer sore throat within the first 24 hour after extubation', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'all patients in both groups were analyzed'}, {'type': 'OTHER_PRE_SPECIFIED', 'title': 'the Incidence of Dysphonia', 'denoms': [{'units': 'Participants', 'counts': [{'value': '30', 'groupId': 'OG000'}, {'value': '30', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'the Traditional Endotracheal Tube', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}, {'id': 'OG001', 'title': 'Prone Ventilation Endotracheal Tube', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.\n\nprone ventilation endotracheal tube: some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes'}], 'classes': [{'categories': [{'measurements': [{'value': '0', 'groupId': 'OG000'}, {'value': '0', 'groupId': 'OG001'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'timeFrame': 'within the first 24 hour after extubation', 'description': 'count the number who suffered dysphonia within the first 24 hour after extubation', 'unitOfMeasure': 'Participants', 'reportingStatus': 'POSTED', 'populationDescription': 'all patients in both groups were analyzed'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Traditional Endotracheal Tube(TT)', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}, {'id': 'FG001', 'title': 'Prone Position Endotracheal Tube(PPT)', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.\n\nprone ventilation endotracheal tube: some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes'}], 'periods': [{'title': 'Overall Study', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '30'}, {'groupId': 'FG001', 'numSubjects': '30'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '30'}, {'groupId': 'FG001', 'numSubjects': '30'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '0'}, {'groupId': 'FG001', 'numSubjects': '0'}]}]}], 'recruitmentDetails': 'We have 80 adult patients as candidates who were undergoing the neurosurgery or spinal surgery in Xiangya Hospital affiliated to Central South University between Mar 11, 2014 and Mar 16, 2016. These participants were graded American society of anesthesia(ASA)I-II,and aged 30-70 years old,weighted ranging from 50 to 75 kilograms.', 'preAssignmentDetails': "We finally enrolled 60 patients for our trail. Among the 80 candidates, 7 patients couldn't meet our inclusion criteria; the other 13 patients refused to participate in this trail at last."}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '30', 'groupId': 'BG000'}, {'value': '30', 'groupId': 'BG001'}, {'value': '60', 'groupId': 'BG002'}]}], 'groups': [{'id': 'BG000', 'title': 'Prone Position Endotracheal Tube(PPT)', 'description': 'We enrolled total 60 adult patients undergoing prone position ventilation surgery,and randomized to each group.30 subjects were involved in the prone position endotracheal tube group(PPT), in which group the patients were intubated with the custom-designed endotracheal tube.'}, {'id': 'BG001', 'title': 'Traditional Endotracheal Tube(TT)', 'description': 'We enrolled total 60 adult patients undergoing prone position ventilation surgery,and randomized to each group.30 subjects were involved in the traditional endotracheal tube group(TT), in which group the patients were intubated with the routine endotracheal tube.'}, {'id': 'BG002', 'title': 'Total', 'description': 'Total of all reporting groups'}], 'measures': [{'title': 'Age, Categorical', 'classes': [{'categories': [{'title': '<=18 years', 'measurements': [{'value': '0', 'groupId': 'BG000'}, {'value': '0', 'groupId': 'BG001'}, {'value': '0', 'groupId': 'BG002'}]}, {'title': 'Between 18 and 65 years', 'measurements': [{'value': '30', 'groupId': 'BG000'}, {'value': '30', 'groupId': 'BG001'}, {'value': '60', 'groupId': 'BG002'}]}, {'title': '>=65 years', 'measurements': [{'value': '0', 'groupId': 'BG000'}, {'value': '0', 'groupId': 'BG001'}, {'value': '0', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'calculatePct': False, 'unitOfMeasure': 'Participants'}, {'title': 'Age, Continuous', 'classes': [{'categories': [{'measurements': [{'value': '49', 'spread': '5', 'groupId': 'BG000'}, {'value': '47', 'spread': '6', 'groupId': 'BG001'}, {'value': '48', 'spread': '6', 'groupId': 'BG002'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'yr', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '15', 'groupId': 'BG000'}, {'value': '14', 'groupId': 'BG001'}, {'value': '29', 'groupId': 'BG002'}]}, {'title': 'Male', 'measurements': [{'value': '15', 'groupId': 'BG000'}, {'value': '16', 'groupId': 'BG001'}, {'value': '31', 'groupId': 'BG002'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Region of Enrollment', 'classes': [{'title': 'China', 'categories': [{'measurements': [{'value': '30', 'groupId': 'BG000'}, {'value': '30', 'groupId': 'BG001'}, {'value': '60', 'groupId': 'BG002'}]}]}], 'paramType': 'NUMBER', 'unitOfMeasure': 'participants'}], 'populationDescription': 'all participants in both groups were analyzed'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'PREVENTION', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 60}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2015-09', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2017-03', 'completionDateStruct': {'date': '2016-09', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2017-03-30', 'studyFirstSubmitDate': '2015-04-26', 'resultsFirstSubmitDate': '2016-12-07', 'studyFirstSubmitQcDate': '2015-05-16', 'lastUpdatePostDateStruct': {'date': '2017-06-15', 'type': 'ACTUAL'}, 'resultsFirstSubmitQcDate': '2017-03-30', 'studyFirstPostDateStruct': {'date': '2015-05-20', 'type': 'ESTIMATED'}, 'resultsFirstPostDateStruct': {'date': '2017-06-15', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2016-09', 'type': 'ACTUAL'}}, 'outcomesModule': {'otherOutcomes': [{'measure': 'the Incidence of Dysphagia', 'timeFrame': 'within the first 24 hours after extubation', 'description': 'count the number who suffered the dysphagia within the first 24 hours after extubation'}, {'measure': 'the Incidence of Sore Throat', 'timeFrame': 'within the first 24 hour after extubation', 'description': 'count the number who suffer sore throat within the first 24 hour after extubation'}, {'measure': 'the Incidence of Dysphonia', 'timeFrame': 'within the first 24 hour after extubation', 'description': 'count the number who suffered dysphonia within the first 24 hour after extubation'}], 'primaryOutcomes': [{'measure': 'Displacement of the Endotracheal Tube', 'timeFrame': 'Participants were followed for the duration of surgery, an average of 2 hours.', 'description': 'We divided the degree of the displacement of the endotracheal tube into 3 kinds, which included mild(displacement distance\\<0.5cm),moderate(0.5cm≤displacement distance\\<1.5cm),severe (1.5cm≤displacement distance).'}], 'secondaryOutcomes': [{'measure': 'The Number of the Prolapse of Endotracheal Tube', 'timeFrame': 'At any time within the procedure of the whole surgery', 'description': 'Counting the number who occured the prolapse of endotracheal tube in both groups'}, {'measure': 'the Degree of Loose or Dampness of the Tape', 'timeFrame': 'at the time when patients were turning to supine position', 'description': 'counting and quantifying the number who occured the dampness or loose of the tape in both groups'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Prone position ventilation', 'Endotracheal intubation', 'Displacement'], 'conditions': ['Mechanical Ventilation Complication']}, 'referencesModule': {'references': [{'pmid': '18211991', 'type': 'BACKGROUND', 'citation': 'Edgcombe H, Carter K, Yarrow S. Anaesthesia in the prone position. Br J Anaesth. 2008 Feb;100(2):165-83. doi: 10.1093/bja/aem380.'}, {'pmid': '8251716', 'type': 'BACKGROUND', 'citation': 'Korn S, Schubert A, Barnett G. Endotracheal tube obstruction during stereotactic craniotomy. J Neurosurg Anesthesiol. 1993 Oct;5(4):272-5. doi: 10.1097/00008506-199310000-00008.'}, {'pmid': '21286458', 'type': 'BACKGROUND', 'citation': 'Choi RM, Yoon JS, Noh JH, Kang KO, Ryu SW, Jun HJ, Cho SS. Airway obstruction by extrinsic tracheal compression during spinal surgery under prone position -A case report-. Korean J Anesthesiol. 2010 Dec;59 Suppl(Suppl):S45-8. doi: 10.4097/kjae.2010.59.S.S45. Epub 2010 Dec 31.'}, {'pmid': '17510044', 'type': 'BACKGROUND', 'citation': 'Soundararajan N, Cunliffe M. Anaesthesia for spinal surgery in children. Br J Anaesth. 2007 Jul;99(1):86-94. doi: 10.1093/bja/aem120. Epub 2007 May 17.'}, {'pmid': '18359427', 'type': 'BACKGROUND', 'citation': 'Tiruvoipati R, Bangash M, Manktelow B, Peek GJ. Efficacy of prone ventilation in adult patients with acute respiratory failure: a meta-analysis. J Crit Care. 2008 Mar;23(1):101-10. doi: 10.1016/j.jcrc.2007.09.003.'}, {'pmid': '20473258', 'type': 'BACKGROUND', 'citation': 'Gattinoni L, Carlesso E, Taccone P, Polli F, Guerin C, Mancebo J. Prone positioning improves survival in severe ARDS: a pathophysiologic review and individual patient meta-analysis. Minerva Anestesiol. 2010 Jun;76(6):448-54.'}, {'pmid': '20130832', 'type': 'BACKGROUND', 'citation': 'Sud S, Friedrich JO, Taccone P, Polli F, Adhikari NK, Latini R, Pesenti A, Guerin C, Mancebo J, Curley MA, Fernandez R, Chan MC, Beuret P, Voggenreiter G, Sud M, Tognoni G, Gattinoni L. Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med. 2010 Apr;36(4):585-99. doi: 10.1007/s00134-009-1748-1. Epub 2010 Feb 4.'}, {'pmid': '23216936', 'type': 'BACKGROUND', 'citation': 'Zou W, Zhang W, Li X, Guo Q. A randomized crossover comparison of the prone ventilation endotracheal tube versus the traditional endotracheal tube in pediatric patients undergoing prone position surgery. Paediatr Anaesth. 2013 Jan;23(1):98-100. doi: 10.1111/pan.12068. No abstract available.'}, {'pmid': '28496141', 'type': 'DERIVED', 'citation': 'Zou W, Shao J, Liang X, Li L, He Z, Guo Q. A randomized comparison of the prone ventilation endotracheal tube versus the traditional endotracheal tube in adult patients undergoing prone position surgery. Sci Rep. 2017 May 11;7(1):1769. doi: 10.1038/s41598-017-02006-6.'}]}, 'descriptionModule': {'briefSummary': 'In this study, the investigators adopt the special endotracheal tube to those patients at prone posture during the operation,or those with acute respiratory distress syndrome in the intensive care unit(ICU), so that the investigators can reduce, or even avoid some severe complications during perianesthesia, and that the investigators can provide strong safeguard measures for the respiratory therapy of critical patients in ICU.', 'detailedDescription': 'The investigators apply some technical proposals to make it come true:one kind of special endotracheal tube, including traditional endotracheal tube,fixed device,fixed rope,two through holes.With this tube ,the investigators can keep away shifting and falling off of traditional air tube,so that the investigators can try to avoid disaster events.And for the patients with acute respiratory disease syndrome(ARDS),they are always given ventilation in prone position,so it may be beneficial.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n\\- those who are about to undergo the surgery at prone posture,especially in neurosurgery and spine surgery，American society of anesthesia(ASA) grade I-II，aged from 18 to 65 years old,weight ranged from 50 to 75 kilograms.\n\nExclusion Criteria:\n\n* No meeting inclusion criteria'}, 'identificationModule': {'nctId': 'NCT02449356', 'briefTitle': 'Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition', 'organization': {'class': 'OTHER', 'fullName': 'Central South University'}, 'officialTitle': 'Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition', 'orgStudyIdInfo': {'id': '2013L14'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'prone position endotracheal tube(PPT)', 'description': 'the subjects of this arm are given the prone ventilation endotracheal tube which contains fixed device, fixed rope.', 'interventionNames': ['Device: prone position endotracheal tube(PPT)']}, {'type': 'NO_INTERVENTION', 'label': 'traditional endotracheal tube(TT)', 'description': 'the subjects of this arm are given the routine endotracheal tube.'}], 'interventions': [{'name': 'prone position endotracheal tube(PPT)', 'type': 'DEVICE', 'description': 'some special kind of endotracheal tube,including traditional air tube ,fixed device, fixed rope, and two through holes', 'armGroupLabels': ['prone position endotracheal tube(PPT)']}]}, 'contactsLocationsModule': {'locations': [{'zip': '410013', 'city': 'Changsha', 'state': 'Hunan', 'country': 'China', 'facility': 'Wangyuan Zou', 'geoPoint': {'lat': 28.19874, 'lon': 112.97087}}], 'overallOfficials': [{'name': 'Wangyuan Zou, MD,phD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Xiangya Hospital'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Wangyuan Zou', 'class': 'OTHER'}, 'collaborators': [{'name': 'Central South University', 'class': 'OTHER'}], 'responsibleParty': {'type': 'SPONSOR_INVESTIGATOR', 'investigatorTitle': 'postgraduate tutor', 'investigatorFullName': 'Wangyuan Zou', 'investigatorAffiliation': 'Central South University'}}}}